Recurrent thromboembolism as a hallmark of Cushing's syndrome

Journal of Endocrinological Investigation

Volumn 20, Issue 4, 1997, Pages 211-214

  La Brocca, A ^a,d   Terzolo, M ^b   Pia, A ^b   Paccotti, P ^b   De Giuli, P ^c   Angeli, A ^b  

^a Ospedale Civile di Giaveno   (Italy)

^b Cattedra di Medicina Interna   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d NONE   (Italy)

Author keywords

Cushing's syndrome; Ketoconazole treatment; Recurrent thromboembolism

Indexed keywords

CORTICOTROPIN; DEXAMETHASONE; HYDROCORTISONE;

ADRENAL CORTEX ADENOMA; ADULT; ARTICLE; CANCER SURGERY; CASE REPORT; CLINICAL EXAMINATION; CUSHING SYNDROME; ENDOCRINE FUNCTION TEST; FEMALE; HUMAN; HYDROCORTISONE URINE LEVEL; HYPERCOAGULABILITY; HYPERCORTISOLISM; MICROADENOMA; PHYSICAL EXAMINATION; RECURRENT DISEASE; SCREENING TEST; THROMBOEMBOLISM;

EID: 0030878142     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03346905     Document Type: Article

References (20)

1. Sjoberg H.E., Blomback M., Granberg P.O. Thromboembolic complications, heparin treatment and increase in coagulation factors in Cushing's syndrome. Acta Med. Scand. 199: 95, 1976.
2. Dal Bo Zanon R., Fornasiero L., Boscaro M., Cappellato G., Fabris F., Girolami A. Increased factor VIII associated activities in Cushing's syndrome: a probable hypercoagulable state. Throm. Haemostas. 47: 116, 1982.
3. Patrassi G.M., Dal Bo Zanon R., Boscaro M., Martinelli S., Girolami A. Further studies on the hypercoagulable state of patients with Cushing's syndrome. Thromb. Haemostas. 54: 518, 1985.
4. Blichert-Toft M. Bagerskov A., Lockwood K., Hasner E. Operative treatment, surgical approach, and related complications in 195 operations upon the adrenal glands. Surg. Gynecol. Obstet. 135: 261, 1972.
5. Casonato A., Pontara E., Bertomoro A., Scarpa E., Sonino N., Girolami A. Abnormalities of primary haemostasis with consequent hypercoagulable state in patients with Cushing's syndrome. J. Endocrinol. Invest. 18(Suppl. no. 5): 75, 1995, abstract number 256.
6. Ikkala E., Myllyla G., Pelkonen R., Rasi V., Viinikka L., Ylikorkala O. Haemostatic parameters in Cushing's syndrome. Acta Med. Scand. 217: 507, 1985.
7. Patrassi G.M., Sartori M.T., Viero M.L., Scarano L., Boscaro M., Girolami A. The fibrinolytic potential in patients with Cushing's disease: a clue to their hypercoagulable state. Blood Coagul. Fibrinolysis 3: 789, 1992.
8. Simmons P.S., Miles J.M., Gerich J.E., Haymond M.W. Increased proteolysis. An effect of increased in plasma cortisol within the physiological range. J. Clin. Invest. 73: 412, 1984.
9. Huges A., McVerry B.A., Wilkinson L., Goldstone A.M., Lewis D., Bloom A. Diabetes, a hypercoagulable state? Haemostatic variables in newly diagnosed type 2 diabetic patients. Acta Haematol. 69: 254, 1983.
10. Boneu B., Durand D., Connilon F., Charlet J.P., Bierme R., Sue G.M. Increased level in factor VIII complex in severe arterial hypertension. Haemostasis 7: 332, 1978.
11. Patrassi G.M., Fallo F., Martinelli S., Mantero F., Boeri G., Girolami A. The contact phase of blood coagulation and renin activation in essential hypertension before and after captopril. Eur. Heart J. 5: 561, 1984.
12. Jorgensen M., Bonnevie-Nielsen V. Increased concentration of the fast-acting plasminogen activator inhibitor in plasma associated with familial venous thrombosis. Br. J. Haematol. 65: 175, 1987.
13. Engesser L., Brommer E.G.P., Kluft C., Briet E. Elevated plasminogen activator inhibitor (PAI), a cause of thrombophilia? A study in 203 patients with familial or sporadic venous thrombophilia. Thromb. Haemostas. 62: 673, 1989.
14. Patrassi G.M., Sartori M.T., Viero M., Boscaro M., Boeri G., Girolami A. Venous thrombosis and tissue plasminogen activator release deficiency: a family study. Blood Coagul. Fibrinol. 2: 231, 1991.
15. Petaja J., Rasi V., Myllyla G., Vahtera E., Hallman H. Familial hypofibrinolysis and venous thrombosis. Br. J. Haematol. 71: 393, 1989.
16. Korninger C., Lechner K., Neissner H., Gossinger H., Kundi M. Impaired fibrinolytic capacity predisposes for recurrence of venous thrombosis. Thromb. Haemostas. 52: 127, 1984.
17. O'Connor N.T.J., Cederholm-Williams S.A., Fletcher E.W., Allington M., Sharp A.A. Significance of idiopathic deep venous thrombosis. Postgrad. Med. J. 60: 275, 1984.
18. Atkinson A.B., Kennedy A.L., Carson D.J., Hadden D.R., Weaver J.A., Sheridan B. Five cases of cyclical Cushing's syndrome. Br. Med. J. 292: 1453, 1985.
19. Schweikert H.U., Fehm H.L., Fahlbusch R., Martin R., Kolloch R., Higuchi M., Kruck F. Cyclic Cushing's syndrome combined with cortisol suppressible, dexamethasone non-suppressible ACTH secretion: a new variant of Cushing's syndrome. Acta Endocrinol. (Copenh.) 110: 289, 1985.
20. Sheeler L.R., Bay J.W. Normal overnight dexamethasone suppression tests (ODST) in patients with proven Cushing's disease. In: Landolt A.M. et al. (Eds.), Advances in Pituitary Adenoma Reserch (Advances in the Biosciences, vol. 69). Pergamon Press, New York, 1988, p. 373.