Clinical response to ketoconazole of HIV-related oral candidosis is predicted by Odds' relative growth method of susceptibility testing

Journal of Antimicrobial Chemotherapy

Volumn 40, Issue 1, 1997, Pages 117-119

  Cartledge, J D ^a   Midgley, J ^a   Gazzard, B G ^a  

^a CHELSEA AND WESTMINSTER HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; KETOCONAZOLE;

ARTICLE; DRUG RESPONSE; DRUG SENSITIVITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; THRUSH;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIFUNGAL AGENTS; CANDIDA; CANDIDIASIS, ORAL; FLUCONAZOLE; HUMANS; KETOCONAZOLE; MICROBIAL SENSITIVITY TESTS; PREDICTIVE VALUE OF TESTS;

EID: 0030877791     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/40.1.117     Document Type: Article

References (9)

1. Odds, F. C. (1992). Antifungal susceptibility testing of Candida spp. by relative growth measurement at single concentrations of antifungal agents. Antimicrobial Agents and Chemotherapy 36, 1727-37.
2. Cartledge, J. D., Midgley, J. & Gazzard, B. G. (1996). Relative growth measurement of Candida species in a single concentration of fluconazole predicts the clinical response to fluconazole of HIV infected patients with oral candidosis. Journal of Antimicrobial Chemotherapy 37, 275-83.
3. Lake-Bakaar, G., Tom, W., Lake-Bakaar, D. et al. (1988). Gastrophy and ketoconazole malabsorption in the acquired immunodeficiency syndrome (AIDS). Annals of Internal Medicine 109, 471-3.
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5. Vanden Bossche, H., Marichal, P., Gorrens, J., Bellens, D., Moereels, H. & Janssen, P. A. J. (1990). Mutation of cytochrome P-450-dependent 14 alpha-demethylase results in decreased affinity for azole antifungals. Biochemical Society Transactions 18, 56-9.
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7. Hitchcock, C. A., Pye, G. W., Troke, P. F., Johnson, E. M. & Warnock, D. W. (1993). Fluconazole resistance in Candida glabrata. Antimicrobial Agents and Chemotherapy 37, 1962-5.
8. Sanglard, D., Kuchler, K., Ischer, F., Pagani, J.-L., Monod, M. & Bille, J. (1995). Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrobial Agents and Chemotherapy 39, 2378-86.
9. Clark, F. S., Parkinson, T., Hitchcock, C. A. & Gow, N. A. R. (1996). Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species: possible role for drug efflux in drug resistance. Antimicrobial Agents and Chemotherapy 40, 419-25.