Pharmacokinetics of adriamycin and adriamycinol after intravenous administration of adriamycin to rats with water-deprivation for 48 hours

Research Communications in Molecular Pathology and Pharmacology

Volumn 96, Issue 3, 1997, Pages 299-306

  Lee, Hee J ^a   Lee, Myung G ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; DOXORUBICINOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEHYDRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY CLEARANCE; NONHUMAN; POLYURIA; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; TISSUE DISTRIBUTION; WATER DEPRIVATION;

ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEHYDRATION; DOXORUBICIN; INFUSIONS, INTRAVENOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; WATER DEPRIVATION;

EID: 0030877696     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Ahmad, M., Niazi, S. K., Ahmad, T., Muzaffar, N. A., Nawaz, M. (1992) Effect of dehydration on the disposition kinetics of erythromycin in rabbits. Biopharm. Drug Disposa. 13: 77-82.
2. Bakar, S. K., Niazi, S. (1983) Effect of water-deprivation on aspirin disposition kinetics. J. Pharm. Sci. 72: 1030-1034.
3. Balis, F. M. (1986) Pharmacokinetic drug interactions of commonly used anticancer drugs. Clin. Pharmacokinet. 11: 223-235.
4. Benjamin, R. S., Riggs, C. E., Bachur, N. R. (1973) Pharmacokinetics and metabolism of adriamycin in man. Clin. Pharmacol. Ther. 14: 592-600.
5. Bots, A. M. B., Van Oort, W. J., Noordhoek, J. (1983) Analysis of adriamycin and adriamycinol in microvolumes of rat plasma. J. Chromatogr. 272: 421-427.
6. Chiou, W. L. (1978) Critical evaluation of potential error in pharmacokinetic studies using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve. J. Pharmacokinet. Biopharm. 6: 539-546.
7. Chiou, W. L. (1980) New calculation method of mean total body clearance of drugs and its application to dosage regimens. J. Pharm. Sci. 69:90-91.
8. Daniel, A. R., Stephen, C. P., Keith, A. R., Duane, A. T. (1993) The disposition of doxorubicin on repeated dosing. J. Clin. Pharmacol. 33: 698-702.
9. Eksborg, S., Strandler, H.-S., Edsmyr, F., Naslund, I., Tahvanainen, P. (1985) Pharmacokinetic study of intravenous infusions of adriamycin. Eur. J. Clin. Pharmacol. 28: 205-212.
10. Ha, H. A., Lee, S. H., Kim, S. H., Kim, O. N., Lee, M. G. (1996) Effect of water deprivation for 48 hours on the pharmacokinetics and pharmacodynamics of azosemide in rats. Res. Commun. Mol. Pathol. Pharmacol. 93: 109-128.
11. Huang, J. Y., Kim, O. N., Lee, S. H., Lee, M. G. (1993) Effects of water deprivation on the pharmacokinetics and pharmacodynamics of bumetanide in rats. Biopharm. Drug Disposit. 14: 463-474.
12. Hwang, S. J., Park, J. M., Lee, W. I., Kim, O. N., Lee, M. G. (1995) The effect of water deprivation on the pharmacokinetics of methotrexate in rats. Biopharm. Drug Disposit. 16: 245-250.
13. Kang, M. J., Yoon, W. H., Kim, O. N., Lee, M. G. (1995) Effect of water deprivation for 48 hours on the pharmacokinetics and pharmacodynamics of furosemide in rats. J. Clin. Pharm. Ther. 20: 13-21.
14. Kim, S. H., Choi, Y. M., Lee, M. G. (1993) Pharmacokinetics and pharmacodynamics of furosemide in protein-calorie malnutrition. J. Pharmacokinet. Biopharm. 21: 1-17.
15. Kim, E. J., Yoon, W. H., Lee, W. I., Kim, O. N., Lee, M. G. (1995) The effect of dehydration on the disposition kinetics of propranolol in rats. Biopharm. Drug Disposit. 16: 251-257.
16. Lee, H.-J., Chiou, W. L. (1989) Erythrocytes as barriers for drug elimination in the isolated rat liver: I. Doxorubicin. Pharm. Res. 6: 833-839.
17. Lee, H. J., Ann, B.-N., Yoon, E. J., Paik, W. H., Shim, C.-K., Lee, M. G. (1995) Pharmacokinetics and tissue distribution of adriamycin and adriamycinol after intravenous administration of adriamycin-loaded neutral proliposomes to rats. Int. J. Pharm. 121: 1-10.
18. Lee, H. J., Ahn, B.-N., Paik, W. H., Shim, C.-K., Lee, M. G. (1996) Inverse targeting of reticuloendothelial system-rich organs after intravenous administration of adriamycin-loaded neutral proliposomes containing poloxamer 407 to rats. Int. J. Pharm. 131: 91-96.
19. Lee, H. J., Paik, W. H., Lee, M. G. (1996a) Pharmacokinetic and tissue distribution changes of adriamycin and adriamycinol after intravenous administration of adriamycin to alloxan-induced diabetes mellitus rats. Res. Commun. Mol. Pathol. Pharmacol. 89: 165-178.
20. Lee, H. J., Paik, W. H., Lee, M. G. (1996b) Pharmacokinetic and tissue distribution changes of adriamycin and adriamycinol after intravenous administration of adriamycin to uranyl nitrate-induced acute renal failure rats. Res. Commun. Mol. Pathol. Pharmacol. 91: 195-204.
21. Prasad, P. P., Niazi, S. (1984) Effect of water-deprivation on antipyrine disposition kinetics in rats. Biopharm. Drug Disposit. 5: 195-198.
22. Prasad, P., Niazi, S., Jung, D. (1988) Effect of acute water deprivation on renal function in rats. Biopharm. Drug Disposit. 9: 259-265.