13-Week inhalation toxicity study of menthol cigarette smoke

Food and Chemical Toxicology

Volumn 35, Issue 7, 1997, Pages 683-692

  Gaworski, C L ^a   Dozier, M M ^a   Gerhart, J M ^b   Rajendran, N ^b   Brennecke, L H ^c   Aranyi, C ^b   Heck, J D ^a  

^a LORILLARD TOBACCO COMPANY   (United States)

^b IIT RESEARCH INSTITUTE   (United States)

^c CHARLES RIVER LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYHEMOGLOBIN; CIGARETTE SMOKE; COTININE; MENTHOL; NICOTINE; TOBACCO SMOKE;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CHRONIC TOXICITY; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; INHALATION; MALE; NONHUMAN; NOSE SECRETION; RAT;

ADMINISTRATION, INHALATION; ANIMALS; BODY WEIGHT; COTININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; MENTHOL; NICOTINE; ORGAN SIZE; RATS; RATS, INBRED F344; SMOKING;

ANIMALIA; NICOTIANA TABACUM;

EID: 0030877095     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(97)00033-1     Document Type: Article

References (26)

1. Ahijevych K., Gillespie J., Demirchi M. and Jagadeesh J. (1996) Menthol and nonmenthol cigarettes and smoke exposure in black and white women. Pharmacology, Biochemistry and Behavior 53, 355-360.
2. Ayres P. H., Mosberg A. T., Burger G. T., Hayes A. W., Sagartz J. W. and Coggins C. R. E. (1989) Nose-only exposure of rats to carbon monoxide. Inhalation Toxicology 1, 349-363.
3. Baumgartner H. and Coggins C. R. E. (1980) Description of a continuous-smoking inhalation machine for exposing small animals to tobacco smoke. Beiträge zur Tabakforschung 10, 169-174.
4. Boyd E. M. and Sheppard E. P. (1969) A bronchomucotropic action in rabbits from inhaled menthol and thymol. Archives Internationales de Pharmacodynamie et de Thérapie 182, 206-214.
5. Burger G. T., Renne R. A., Sagartz J. W., Ayres P. H., Coggins C. R., Mosberg A. T. and Hayes A. W. (1989) Histologic changes in the respiratory tract induced by inhalation of xenobiotics: physiologic adaptation or toxicity? Toxicology and Applied Pharmacology 101, 521-542.
6. Coggins C. R. E., Lam R. and Morgan K. T. (1982) Chronic inhalation study in rats using cigarettes containing different amounts of Cytrel tobacco supplement. Toxicology 22, 287-296.
7. Coggins C. R. E., Mosberg A. T., Ayres P. H., Sagartz J. W., Burger G. T. and Hayes A. W. (1990) Inhalation comparison in rats of menthol cigarettes which burn or which only heat tobacco. (Abstract). Toxicologist 10, 200.
8. Dalbey W. E., Nettlesheim P., Griesmer R., Caton J. E. and Guerin M. R. (1980) Chronic inhalation of cigarette smoke by F344 rats. Journal of the National Cancer Institute 64, 383-390.
9. Haggard H. and Greenberg L. (1941) Concentration of menthol in the smoke from mentholated cigarettes. Archives of Otolaryngology 33, 711-716.
10. Hebert J. R. and Kabat G. C. (1989) Menthol cigarette smoking and oesophageal cancer. International Journal of Epidemiology 18, 37-44.
11. Hotchkiss J. A., Evans W. A., Chen B. T., Finch G. L. and Harkema J. R. (1995) Regional differences in the effects of mainstream cigarette smoke on stored mucosubstances and DNA synthesis in F344 rat nasal respiratory epithelium. Toxicologv and Applied Pharmacology 131, 316-324.
12. IARC (1985) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Vol. 38. Tobacco Smoking. International Agency for Research on Cancer, Lyon.
13. Jarvik M. E., Tashkin D. P., Caskey N. H., McCarthy W. J. and Rosenblatt M. R. (1994) Mentholated cigarettes decrease puff volume of smoke and increase carbon monoxide absorption. Physiology and Behavior 56, 563-570.
14. Jenkins R., Newman R. and Chavis M. (1970) Cigarette smoke formation studies. Beiträge zur Tabakforschung 5, 299-301.
15. Kabat G. C. and Hebert J. R. (1991) Use of mentholated cigarettes and lung cancer risk. Cancer Research 51, 6510-6513.
16. McCarthy W. J., Caskey N. H., Jarvik M. E., Gross T. M., Rosenblatt M. R. and Carpenter C. (1995) Menthol vs nonmenthol cigarettes: effects on smoking behavior. American Journal of Public Health 85, 67-72.
17. Miller G. E., Jarvik M. E., Caskey N. H., Segerstrom S. C., Rosenblatt M. R. and McCarthy W. J. (1994) Cigarette mentholation increases smokers' exhaled carbon monoxide levels. Experimental and Clinical Psychophartnacology 2, 154-160.
18. Opdyke D. L. J. (1976a) Monographs on fragrance raw materials: l-Menthol. Food and Cosmetics Toxicology 14, 471-472.
19. Opdyke D. L. J. (1976b) Monographs on fragrance raw materials: Menthol racemic. Food and Cosmetics Toxicology 14, 473-474.
20. Penney D. G. (1993) Acute carbon monoxide poisoning in an animal model: the effects of altered glucose on morbidity and mortality. Toxicology 80, 85-101.
21. Rakeiten N., Rakeiten M. L. and Boykin M. (1954) Effects of menthol vapour on the intact animal with special reference to the upper respiratory tract. Journal of the American Pharmaceutical Association 43, 390-392.
22. Sagartz J. W., Madarasz A. J., Forsell M. A., Burger G. T., Ayres P. H. and Coggins C. R. E. (1992) Histological sectioning of the rodent larynx for inhalation toxicity testing. Toxicologic Pathology 20, 118-121.
23. Sidney S., Tekawa I. S., Friedman G. D., Sadler M. C. and Tashkin D. P. (1995) Mentholated cigarette use and lung cancer. Archives of International Medicine 155, 727-732.
24. Van Vunakis H., Gjika H. B. and Langone J. J. (1987) Passive smoking. In Environmental Carcinogens. Methods of Analysis and Exposure Measurement. Vol. 9. IARC Scientific Publications No. 81. International Agency for Research on Cancer, Lyon.
25. Wehner A. P., Dagle G. E., Milliman E. M., Phelps D. W., Carr D. B., Decker J. R. and Filipy R. E. (1981) Inhalation bioassay of cigarette smoke in rats. Toxicology and Applied Pharmacology 61, 1-17.
26. Young J. T. (1981) Histopathologic examination of the rat nasal cavity. Fundamental and Applied Toxicology 1, 309-312.