Autologous transplantation with CD52 monoclonal antibody-purged marrow for acute lymphoblastic leukemia: Long-term follow-up

Leukemia and Lymphoma

Volumn 25, Issue 5-6, 1997, Pages 479-486

  Mehta, Jayesh ^a   Powles, Ray ^a   Treleaven, Jennie ^a   Horton, Clive ^a   Shepherd, Val ^a   Hale, Geoff ^b   Waldmann, Herman ^b   Singhal, Seema ^a  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Acute lymphoblastic leukemia; Autologous bone marrow transplantation; Campath IM; Interstitial pneumonitis purging; Relapse total body irradiation

Indexed keywords

ALEMTUZUMAB; CD52 ANTIGEN; MELPHALAN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW PURGING; CANCER MORTALITY; CANCER RECURRENCE; CANCER REGRESSION; CANCER SURVIVAL; CELL COUNT; CHILD; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUTROPHIL; PRESCHOOL CHILD; PRIORITY JOURNAL; RADIATION SICKNESS; SCHOOL CHILD; SURVIVAL TIME; THROMBOCYTE COUNT; WHOLE BODY RADIATION;

EID: 0030877079     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199709039035     Document Type: Article

References (39)

1. Hoelzer, D. and Gale, R. P. (1987). Acute lymphoblastic leukemia in adults: recent progress, future directions, Semm. Hematol., 24, 27-39.
2. Barnett, M. J., Greaves, M. F., Amess, J A., et al. (1986). Treatment of acute lymphoblastic leukaemia in adults, Br. J. Haematol., 64, 455-468
3. Hoelzer, D , Thiel, E., Löffler, H., et al. (1988). Prognostic factors in a multicenter study for treatment of acute lymphoblastic leukemia in adults, Blood, 71, 123-131.
4. Hussein, K. K., Dahlberg, S., Head, D., et al. (1989). Treatment of acute lymphoblastic leukemia in adults with intensive induction, consolidation, and maintenance chemotherapy, Blood, 73, 57-63.
5. Linker, C. A , Levitt, L. J., O'Donnell, M., Forman, S. J and Ries, C. A. (1991). Treatment of adult acute lymphoblastic leukemia with intensive cyclical chemotherapy: a follow-up report, Blood, 78, 2814-2822.
6. Horowitz, M. M , Messerer, D., Hoelzer, D., et al. (1991). Chemotherapy compared with bone marrow transplantation for adults with acute lymphoblastic leukemia in first remission, Ann. Intern. Med , 115, 13-18.
7. Dicke, K. A. (1992). Role of bone marrow transplant in acute lymphocytic leukemia, Leukemia, 6 (suppl 4), 56-58.
8. Weisdorf, D. J., Nesbit, M. E., Ramsay, N. K., et al. (1987). Allogeneic bone marrow transplantation for acute lymphoblastic leukemia in remission: prolonged survival associated with acute graft-versus-host disease, J. Clin Oncol , 5, 1348-1355.
9. Doney, K., Fisher, L. D., Appelbaum, F. R., et al. (1991). Treatment of adult acute lymphoblastic leukemia with allogeneic bone marrow transplantation. Multivariate analysis of factors affecting acute graft-versus-host disease, relapse, and relapse-free survival, Bone Marrow Transplant., 7, 453-459.
10. Chao, N J., Forman, S J., Schmidt, G. M., et al. (1991). Allogeneic bone marrow transplantation for high-risk acute lymphoblastic leukemia during first complete remission, Blood, 78, 1923-1927.
11. Wingard, J R., Piantadosi, S., Santos, G. W , et al. (1990). Allogeneic bone marrow transplantation for patients with high-risk acute lymphoblastic leukemia. J. Clin. Oncol., 8, 820-830.
12. Blaise, D., Gaspard, M. H., Stoppa, A. M., et al. (1990). Allogeneic or autologous bone marrow transplantation for acute lymphoblastic leukemia in first complete remission, Bone Marrow Transplant , 5, 7-12.
13. Gilmore, M. J. M. L., Hamon, M. D., Prentice, H. G., et al. (1991). Failure of purged autologous bone marrow transplantation in high risk acute lymphoblastic leukaemia in first complete remission, Bone Marrow Transplant., 8, 19-26.
14. Fière, D., Lepage, E., Sebban, C., et al. (1993). Adult acute lymphoblastic leukemia: a multicentric randomized trial testing bone marrow transplantation as postremission therapy, J. Clin. Oncol , 10, 1990-2001.
15. Tiley, C., Powles, R., Treleaven, J., et al. (1993). Feasibility and efficacy of maintenance chemotherapy following autologous bone marrow transplantation for first remission acute lymphoblastic leukaemia, Bone Marrow Transplant., 12, 449-455.
16. Powles, R., Mehta, J., Singhal,. S., et al. (1995). Autologous bone marrow or peripheral blood stem cell transplantation followed by maintenance chemotherapy for adult acute lymphoblastic leukemia in first remission: 50 cases from a single center. Bone Marrow Transplant, 16, 241-247.
17. Ritz, J., Sallan, S E., Bast, R. C., et al. (1982). Autologous bone-marrow transplantation in CALLA-positive acute lymphoblastic leukemia after in-vitro treatment with J5 monoclonal antibody and complement, Lancet, 2, 60-63.
18. Kersey, J. H., Weisdorf, D., Nesbit, M. E., et al. (1987). Comparison of autologous and allogeneic bone marrow transplantation for treatment of high-risk refractory acute lymphoblastic leukemia, N. Engl. J. Med., 317, 461-467.
19. Preijers, F. W., De Witte, T., Wessels, J. M., et al. (1989). Autologous transplantation of bone marrow purged in vitro with anti-CD7-(WT1-) ricin A immunotoxin in T-cell lymphoblastic leukemia and lymphoma. Blood, 74, 1152-1158.
20. Uckun, F. M., Kersey, J. H., Vallera, D. A., et al. (1990). Autologous bone marrow transplantation in high-risk remission T-lineage acute lymphoblastic leukemia using immuno-toxins plus 4-hydroperoxycyclophosphamide for marrow purging, Blood, 76, 1723-1733
21. Yeager, A. M., Rowley, S. D., Kaizer, H. and Santos, G W. (1990). Ex vivo chemopurging of autologous bone marrow with 4-hydroperoxycyclophosphamide to eliminate occult leukemic cells. Laboratory and clinical observations. Am. J. Pediatr. Hematol. Oncol., 12, 245-256.
22. Uckun, F. M., Kersey, J. H., Haake, R., Weisdorf, D. and Ramsay, N. K. (1992). Autologous bone marrow transplantation in high-risk remission B-lineage acute lymphoblastic leukemia using a cocktail of three monoclonal antibodies (BA-1/CD24, BA-2/CD9, and BA-3/CD10) plus complement and 4-hydroperoxycyclophosphamide for ex vivo bone marrow purging, Blood, 79, 1094-1104.
23. Billett, A. L., Kornmehl, E., Tarbell, N. J., et al. (1993). Autologous bone marrow transplantation after a long first remission for children with recurrent acute lymphoblastic leukemia, Blood, 81, 1651-1657.
24. Schmid, H , Henze, G., Schwerdtfeger, R., et al. (1993). Fractionated total body irradiation and high-dose VP-16 with purged autologous bone marrow rescue for children with high risk relapsed acute lymphoblastic leukemia. Bone Marrow Transplant., 12, 597-602.
25. Laporte, J. P., Douay, L., Lopez, M., et al. (1994) One hundred twenty-five adult patients with primary acute leukemia autografted with marrow purged by mafosfamide: a 10-year single institution experience, Blood, 84, 3810-3818.
26. Hale, G., Bright, S., Chumbley, G , et al. (1983). Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement, Blood, 62, 873-882.
27. Hale, G. and Waldmann, H. (1994). CAMPATH-1 monoclonal antibodies in bone marrow transplantation, J. Hematother., 3, 15-31.
28. Gazitt, Y., Or, R., Mumcuoglu, M. and Slavin, S. (1987). Monoclonal rat anti-human lymphocyte antibody Campath-1 binds to T and B lymphocytes but effectively lyses only T cells, Bone Marrow Transplant., 2, 427-433.
29. Naparstek, E , Or, R., Nagler, A., et al. (1995). T-cell-depleted allogeneic bone marrow transplantation for acute leukaemia using Campath-1 antibodies and post-transplant administration of donor's peripheral blood lymphocytes for prevention of relapse. Br. J. Haematol., 89, 506-515.
30. Hale, G., Swirsky, D., Waldmann, H. and Chan, L. C. (1985). Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation, Br. J. Haematol , 60, 41-48.
31. Hale, G., Dyer, M. J. S , Clark, M. R., et al. (1988). Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H. Lancet, 2, 1394-1399.
32. Dyer, M. J. S., Hale, G., Hayhoe, F. G. and Waldmann, H. (1989). Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype, Blood, 73, 1431-1439.
33. Yeager, A. M., Kaizer, H., Santos, G. W., et al. (1986). Autologous bone marrow transplantation in patients with acute nonlymphocytic leukemia, using ex vivo marrow treatment with 4-hydroperoxycyclophosphamide, N. Engl. J. Med., 315, 141-147.
34. Gorin, N. C. Labopin, M., Meloni, G., et al. (1991). Autologous bone marrow transplantation for acute myeloblastic leukemia in Europe: further evidence of the role of marrow purging by mafosfamide. European Co-operative Group for Bone Marrow Transplantation (EBMT), Leukemia, 5, 896-904.
35. Mehta, J., Powles, R., Horton, C., Treleaven, J. and Singhal, S. (1996). Factors affecting engraftment and hematopoietic recovery after unpurged autografting in acute leukemia, Bone Marrow Transplant., 18, 319-324.
36. Mehta, J. (1993). Graft-versus-leukemia reactions in clinical bone marrow transplantation. Leuk Lymphoma, 10, 427-432.
37. Brenner, M K., Rill, D. R., Moen, R. C., et al. (1993). Gene-marking to trace origin of relapse after autologous bone-marrow transplantation, Lancet, 341, 85-86.
38. Hale, G and Waldmann, H. (1995). Availability of Campath-1 antibodies for bone marrow transplantation, Bone Marrow Transplant., 15, 327.
39. Riechmann, L., Clark, M., Waldmann, H. and Winter, G. (1988). Reshaping human antibodies for therapy, Nature, 332, 323-327