Production of interleukin-6 induced by hypoxia linked to peripheral arterial disease

Annals of the New York Academy of Sciences

Volumn 811, Issue , 1997, Pages 542-548

  Baba, Toshiya ^a   Uchimura, Isao ^b   Fujisawa, Kazuhiko ^b   Morohoshi, Masaharu ^b   Asaoka, Hiroshi ^b   Tanaka, Akira ^b   Numano, Fujio ^b  

^a Kawaguchi Kogyo General Hospital   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; MESSENGER RNA;

ARTERY DISEASE; CONFERENCE PAPER; HUMAN; HUMAN CELL; HYPOXIA; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030876716     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb52038.x     Document Type: Conference Paper

References (24)

1. FOWKES, F. G., J. P. PELL, P. T. DONNAN, E. HOUSLEY, G. D. LOWE, R. A. RIEMERSMA & R. J. PRESCOTT. 1994. Sex differences in susceptibility to etiologic factors for peripheral atherosclerosis. Importance of plasma fibrinogen and blood viscosity. Arterioscler. Thromb. 14: 862-868.
2. WILHELMSEN, L., K. SVARDSUDD, K. KORSAN-BENGTSEN, B. LARSSON, L. WELIN & G. TIBBLIN. 1984. Fibrinogen as a risk factor for stroke and myocardial infarction. N. Engl. J. Med. 311: 501-505.
3. KANNEL, W. B., P. A. W. WOLF, W. P. CASTELLI & R. B. D'AGOSTINO. 1987. Fibrinogen and risk of cardiovascular disease. The Framingham study. J. Am. Med. Assoc. 258: 1183-1186.
4. SMITH, G. D. & M. J. SHIPLEY. 1990. Intermittent claudication, heart disease risk factors, and mortality: the Whitehall study. Circulation 82: 1925-1931.
5. EAGLE, K. A., C. S. RIHAL, E. D. FOSTER, M. C. MICKEL & B. J. GERSH. 1994. Long-term survival in patients with coronary artery disease: importance of peripheral vascular disease. J. Am. Coll. Cardiol. 23: 1091-1095.
6. CASTELL, J. V., M. J. GOMEZ-LECHON, M. DAVID, T. ANDUS, T. GEIGER, R. TRULLENQUE, R. FABRA & P. C. HEINRICH. 1989. Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes. FEBS Lett. 242: 237-239.
7. MACKIEWICZ, A., T. SPEROFF, M. K. GANAPATHI & I. KUSHNER. 1991. Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines. J. Immunol. 146: 3032-3037.
8. HAEGEMAN, G., J. CONTENT, G. VOLCKAERT, R. DERYNCK, J. TAVERNIER & W. FIERS. 1986. Structural analysis of the sequence coding for an inducible 26-kDa protein in human fibroblasts. Eur. J. Biochem. 159: 625-632.
9. JIRIK, F. R., T. J. PODOR, T. HIRANO, T. KISHIMOTO, D. J. LOSKUTOFF, D. A. CARSON & M. LOTZ. 1989. Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J. Immunol. 142: 144-147.
10. HORII, Y., A. MURAGUCHI, S. SUEMATSU, T. MATSUDA, K. YOSHIZAKI, T. HIRANO & T. KISHIMOTO. 1988. Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T-cells. J. Immunol. 141: 1529-1535.
11. YAMAUCHI-TAKIHARA, K., Y. IHARA, A. OGATA, K. YOSHIZAKI, J. AZUMA & T. KISHIMOTO. 1995. Hypoxic stress induces cardiac myocyte-derived interleukin-6. Circulation 91: 1520-1524.
12. HELFGOTT, D. C., S. B. TATTER, U. SANTHANAM, R. H. CLARICK, N. BHARDWAJ, L. T. MAY & P. B. SEHGAL. 1989. Multiple forms of IFN-beta 2/IL-6 in serum and body fluids during acute bacterial infection. J. Immunol. 142: 948-953.
13. LIBERT, C., A. VINK, P. COULIE, P. BROUCKAERT, B. EVERAERDT, J. VAN SNICK & W. FIERS. 1992. Limited involvement of interleukin-6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin-6 or its receptor in various murine models. Eur. J. Immunol. 22: 2625-2630.
14. HIRANO, T., T. MATSUDA, M. TURNER, N. MIYASAKA, G. BUCHAN, B. TANG, K. SATO, M. SHIMIZU, R. MAINI, M. FELDMANN & T. KISHIMOTO. 1988. Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis. Eur. J. Immunol. 18: 1797-1801.
15. HIRANO, T., T. TAGA, K. YASUKAWA, K. NAKAJIMA, N. NAKANO, F. TAKATSUKI, M. SHIMIZU, A. MURASHIMA, S. TSUNASAWA, F. SAKIYAMA & T. KISHIMOTO. 1987. Human B cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production. Proc. Natl. Acad. Sci. USA 84: 228-231.
16. HORII, Y., A. MURAGUCHI, M. IWANO, T. MATSUDA, T. HIRAYAMA, H. YAMADA, Y. FUJII, K. DOHI, H. ISHIKAWA, Y. OHMOTO, K. YOSHIZAKI, T. HIRANO & T. KISHIMOTO. 1989. Involvement of IL-6 in mesangial proliferative glomerulonephritis. J. Immunol. 143: 3949-3955.
17. KOHASE, M., L. T. MAY, I. TAMM, J. VILCEK & P. B. SEHGAL. 1987. A cytokine network in human diploid fibroblasts: interactions of beta-interferons, tumor necrosis factor, platelet-derived growth factor, and interleukine 1. Mol. Cell Biol. 7: 273-280.
18. BROUCKAERT, P., D. R. SPRIGGS, G. DEMETRI, D. W. KUFE & W. FIERS. 1989. Circulating interleukin 6 during infusion of tumor necrosis factor and interferon γ. J. Exp. Med. 169: 2257-2262.
19. FONG, Y., L. L. MOLDAWER, H. WEI, S. B. TATTER, R. H. CLARICK, U. SANTHANAM, D. SHERRIS, L. T. MAY, P. B. SEGHAL & S. F. LOWRY. 1989. Endotoxemia elicits increased circulating β2/IL-6 in man. J. Immunol. 142: 2321-2324.
20. MOROHOSHI, M., K. FUJISAWA, I. UCHIMURA & F. NUMANO. 1995. The effect of glucose and advanced glycosylation end products on IL-6 production by human monocytes. Ann. N.Y. Acad. Sci. 748: 562-570.
21. SALOMON, R. N., R. UNDERWOOD, M. V. DOYLE, A. WANG & P. LIBBY. 1992. Increased apolipoprotein E and c fms gene expression without elevated interleukin 1 or 6 mRNA levels indicates selective activation of macrophage functions in advanced human atheroma. Proc. Natl. Acad. Sci. USA 89: 2814-2818.
22. LIUZZO, G., L. M. BIASUCCI, J. R. GALLIMORE, R. L. GRILLO, A. G. REBUZZI, M. B. PEPYS & A. MASERI. 1994. The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina. N. Engl. J. Med. 331: 417-424.
23. HAVERKATE, F., S. G. THOMPSON & F. DUCKERT. 1995. Haemostasis factors in angina pectoris; relation to gender, age and acute-phase reaction. Results of the ECAT angina pectoris study group. Thromb. Haemost. 73: 561-567.
24. KOHCHI, K., S. TAKEBAYASHI, T. HIROKI & M. NOBUYOSHI. 1985. Significance of adventitial inflammation of the coronary artery in patients with unstable angina: results at autopsy. Circulation 71: 709-716.