Quinolinic acid production by macrophages stimulated with IFN-γ, TNF- α, and IFN-α

Journal of Interferon and Cytokine Research

Volumn 17, Issue 10, 1997, Pages 589-595

  Pemberton, Louise A ^a   Kerr, Stephen J ^a   Smythe, George ^b   Brew, Bruce J ^a,c  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ENDOTOXIN; GAMMA INTERFERON; QUINOLINIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BRAIN DISEASE; CELL DEATH; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; INFLAMMATORY CELL; MACROPHAGE FUNCTION; MASS SPECTROMETRY; MYCOPLASMA; NEUROPSYCHOLOGY; NEUROTOXICITY; PRIORITY JOURNAL; VIRUS INFECTION;

EID: 0030875855     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1997.17.589     Document Type: Article

References (47)

1. HEYES, M.P., SAITO, K., and MARKEY, S.P. (1992). Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid. Biochem. J. 283, 633-635.
2. BREW, B.J., CORBEIL, J., PEMBERTON, L., EVANS, L., SAITO, K., PENNY, R., COOPER, D.A., and HEYES, M.P. (1995). Quinolinic acid production is related to macrophage tropic isolates of HIV-1. J. Neurovirol. 1, 369-374.
3. HEYES, M.P., SAITO, K., CROWLEY, J.S., DAVIS, L.E., DEMITRACK, M.A., DER, M., DILLING, L.A., ELIA, J., KRUESI, M.J.P., LACKNER, A., LARSEN, S.A., LEE, K., LEONARD, H.L., MARKEY, S.P., MARTIN, A., MILSTEIN, S., MOURADIAN, M.M., PRANZATELLI, M.R., QUEARRY, B.J., SALAZAR, A., SMITH, M., STRAUSS, S.E., SUNDERLAND, T., SWEDO, S.W., and TOURTELLOTTE, W.W. (1992). Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain 115, 1249-1273.
4. BREW, B.J., ROSENBLUM, M.R., CRONIN, K., and PRICE, R.W. (1995). Human immunodeficiency virus in brain and correlation with dementia. Ann. Neurol. 38, 563-570.
5. SCHWARCZ, R., WHETSELL, W.O., and MANGANO, R.E.M. (1983). Quinolinic acid: an endogenous metabolite can produce axon sparing lesions in rat brain. Science 219, 316-318.
6. REINHARD, J.F., ERICKSON, J.B., and FLANAGAN, E.M. (1994). Quinolinic acid in neurologic disease: opportunities for novel drug development. Adv. Pharmacol. 30, 85-127.
7. KIM, J.P., and CHOI, D.W. (1987). Quinolinate neurotoxicity in cortical cell culture. Neuroscience 23, 423-432.
8. KIDA, E., and MATYJA, E. (1988). Ultrastructural alterations induced by quinolinic acid in organotypic culture of rat hippocampus. Clin. Neuropathol. 7, 176.
9. WHETSELL, W.O., and SCHWARCZ, R. (1989). Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system. Neurosci. Lett. 97, 271-275.
10. KERR, S.J., ARMATI, P.J., and BREW, B.J. (1995). Neurocytotoxicity of quinolinic acid in human brain cultures. J. Neurovirol. 1, 375-380.
11. HEYES, M.P., BREW, B.J., MARTIN, A., PRICE, R.W., SALAZAR, A.M., SIDTIS, J.J., YERGEY, J.A., MOURADIAN, M.M., SADLER, A.E., and KEILP, J. (1991). Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status. Ann. Neurol. 29, 202-209.
12. NOTTET, H.S., FLANAGAN, E.M., FLANAGAN, C.R., GELBARD, H.A., GENDELMAN, H.E., and REINHARD, J.F. (1996). The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes. J. Neurovirol. 2, 111-117.
13. WESSELINGH, S.L., POWER, C., GLASS, J.D., TYOR, W.R., McARTHUR, J.C., FARBER, J.M., GRIFFIN, J.W., and GRIFFIN, D.E. (1993). Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann. Neurol. 33, 576-582.
14. RHO, M.B., WESSLINGH, S., GLASS, J.D., McARTHUR, J.C., CHOI, S., and TYOR, W.R. (1995). A potential role for interferon-alpha in the pathogenesis of HIV-associated dementia. Brain Behav. Immun. 9, 366-377.
15. HEYES, M.P., and MARKEY, S.P. (1988). Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations. Ann. Biochem. 174, 349-359.
16. SAITO, K., CHEN, C.Y., MASANA, M., CROWLEY, J.S., MARKEY, S.P., and HEYES, M.P. (1993). 4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-γ-stimulated monocytes (THP-1 cells). Biochem. J. 291, 11-14.
17. WERNER-FELMAYER, G., WERNER, E.R., FUCHS, D., HAUSEN, A., REIBNEGGER, G., and WACHTER, H. (1989). Characteristics of interferon induced tryptophan metabolism in human cells in vitro. Biol. Chem. 370, 1063-1069.
18. WARREN, D., JOHNSON, W.D., MEI, B., and COHN, Z.A. (1977). The separation, long-term cultivation and maturation of the human monocyte. J. Exp. Med. 146, 1613-1625.
19. TRIGLIA, T., BURNS, G.F., and WERKMEISTER, J.A. (1985). Rapid changes in surface antigen expression by blood monocytes cultured in suspension or adherent to plastic. Blood 65, 921-928.
20. KEISARI, Y., BUCANA, C., MARKOVICH, S., and CAMPBELL, D.E. (1990). Interaction between human peripheral blood monocytes and tumor promoters: effect on growth differentiation and function in vitro. J. Biol. Response Mod. 9, 6455-6459.
21. HAYAISHI, O. (1985). Indoleamine-2,3-dioxygenase with special reference to the mechanism of interferon action. Biken J. 28, 39-49.
22. WERNER-FELMEYER, G., WERNER, E.R., FUCHS, D., HAUSEN, A., REIBNEGGER, G., and WACHTER, H. (1990). Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment. Cancer Res. 50, 2863-2867.
23. YOSHIDA, R., URADE, Y., TOKUDA, M., and HAYAISHI, O. (1979). Induction of indoleamine-2,3-dioxygenase in mouse lung during virus infection. Proc. Natl. Acad. Sci. USA 76, 4084-4086.
24. RUBIN, B.Y., ANDERSON, S.L., HELLERMANN, G.R., RICHARDSON, N.K., LUNN, R.M., and VALINSKY, J.E. (1988). The development of antibody to the interferon induced indoleamine-2,3-dioxygenase and the study of the regulation of its synthesis. J. Interferon Res. 8, 691-702.
25. PFEFFERKORN, E.R. (1984). Interferon-γ blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan. Proc. Natl. Acad. Sci. USA 81, 908-912.
26. PFEFFERKORN, E.R., REBHUN, S., and ECKEL, M. (1986). Characterization of an indoleamine-2,3-dioxygenase induced by γ-interferon in cultured human fibroblasts. J. Interferon Res. 6, 267-279.
27. MURRAY, H.W., SZURO-SUDOL, A., WELLNER, D., OCA, M.J., GRANGER, A.M., LIBBY, D.M., ROTHERMEL, C.D., and RUBIN, B.Y. (1989). Role of degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages. Infect. Immun. 57, 845-849.
28. CAPLEN, H.S., and GUPTA, S.L. (1988). Differential regulation of a cellular gene by human interferon-gamma and interferon-alpha. J. Biol. Chem. 263, 332-339.
29. GOGATE, N., KRISTENSSON, K., NORRBY, E., and OLSSON, T. (1991). Gamma interferon expression and major histocompatibility complex induction during measles and vesicular somatitis infections of the brain. J. Neuroimmunol. 31, 19-26.
30. FREI, K., LEIST, T., MEAGER, A., GALLO, P., LEPPERT, D., ZINKERNAGEL, R., and FONTANA, A. (1988). Production of B cell stimulatory factor-2 and interferon-γ in the central nervous system during viral meningitis and encephalitis. J. Exp. Med. 168, 449-453.
31. MEYERS, C.A., SCHEIBEL, R.S., and FORMAN, A.D. (1991). Persistent neurotoxicity of systemically administered interferon-alpha. Neurology 41, 672-676.
32. SHIOZAWA, S., KUROKI, Y., KIM, M., HIROHATA, S., and OGINO, T. (1992). Interferon-alpha in lupus psychosis. Arthritis Rheum. 35, 417-422.
33. PORTA, J., CAROTA, A., PIZZALATO, G.P., WILDI, E., WIDMER, M.C., MARGAIRAZ, C., and GRAU, G.E. (1993). Immunopathological changes in human cerebral malaria. Clin. Neuropathol. 12, 142-146.
34. GRIMALDI, L.M.E., MARTINO, G.V., FRANCIOTTA, D.M., BRUSTIA, R., COSTAGNO, A., PRISTERA, R., and LAZZARIN, A. (1991). Elevated tumor necrosis factor-alpha levels in spinal fluid from HIV-1 infected patients with central nervous system involvement. Ann. Neurol. 29, 21-25.
35. MERRILL, J.E., KOYANAGI, Y., ZACK, J., THOMAS, L., MARTIN, F., and CHEN, I.S. (1992). Induction of interleukin-1 and tumor necrosis factor alpha in brain cultures by human immunodeficiency virus type 1. J. Virol. 66, 2217-2225.
36. MEYERS, C.A., SCHEIBEL, R.S., and FORMAN, A.D. (1991). Persistent neurotoxicity of systemically administered interferon-alpha. Neurology 41, 672-676.
37. MERIMSKY, O., and CHAITCHIK, S. (1992). Neurotoxicity of interferon-alpha. Anticancer Drugs 3, 567-570.
38. KOEHLER, S.M., and GLASS, J.P. (1992). Neurotoxicity of interferon-alpha [Letter, Comment]. Neurology 42, 939.
39. JANSSON, H.L., BERK, L., VERMEULEN, M., and SCHALM, S.W. (1990). Seizures associated with low-dose alpha-interferon [Letter]. Lancet 336, 1580.
40. FÄRKKILÄ, A.M., IIVANAINEN, M.V., and FÄRKKILÄ, M.A. (1990). Disturbance of the water and electrolyte balance during high-dose interferon treatment. J. Interferon Res. 10, 221-227.
41. GLASS, J.D., WESSELINGH, S.L., SELNES, O.A., and McARTHUR, J.C. (1993). Clinical-neuropathologic correlation in HIV-associated dementia. Neurology 43, 2230-2237.
42. TYOR, W., GLASS, J.D., GRIFFIN, J.W., BECKER, P.S., McARTHUR, J.C., BEZMAN, L., and GRIFFIN, D.E. (1992). Cytokine expression in the brain during the acquired immune deficiency syndrome. Ann. Neurol. 31, 349-360.
43. LIPTON, S.A., and GENDELMAN, H.E. (1995). Dementia associated with the acquired immunodeficiency syndrome. N. Engl. J. Med. 332, 934-940.
44. ACHIM, C.L., HEYES, M.P., and WILEY, C.A. (1993). Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains. J. Clin. Invest. 91, 2769-2775.
45. WILT, S.G., MILWARD, E., ZHOU, J.M., NAGASATO, K., PATTON, H., RUSTEN, R., GRIFFIN, D.E., O'CONNOR, M., and DUBOIS-DALCQ, M. (1995). In vitro evidence for a dual role of tumor necrosis factor-alpha in human immunodeficiency virus type 1 encephalopathy. Ann. Neurol. 37, 381-394.
46. MELLORS, J.W., GRIFFITH, B.P., ORTIS, M.A., LANDRY, M.L., and RYAN, J.L. (1991). Tumor necrosis factor-α/cachectin enhances human immunodeficiency virus type 1 replication in primary macrophages. J. Infect. Dis. 163, 78-82.
47. BENVENISTE, E.N., and BENOS, D.J. (1995). TNF-alpha-and IFN-gamma-mediated signal transduction pathways: effects on glial cell gene expression and function. FASEB J. 9, 1577-1584.