-
1
-
-
0023935362
-
Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleotides
-
Hertel LW, Kroin JS, Misner JW, et al. Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleotides. J Org Chem 1988; 53: 2406-9.
-
(1988)
J Org Chem
, vol.53
, pp. 2406-2409
-
-
Hertel, L.W.1
Kroin, J.S.2
Misner, J.W.3
-
2
-
-
0023783698
-
Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosy cytosine
-
Heinemann V, Hertel LW, Grindey GB, Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosy cytosine. Cancer Res 1988; 48: 4024-31.
-
(1988)
Cancer Res
, vol.48
, pp. 4024-4031
-
-
Heinemann, V.1
Hertel, L.W.2
Grindey, G.B.3
Plunkett, W.4
-
3
-
-
0026324313
-
Action of 2′,2′-difluorodeoxycytidine on DNA synthesis
-
Huang P, Chubb S, Hertel LW, Grindey GB, Plunkett W. Action of 2′,2′-difluorodeoxycytidine on DNA synthesis. Cancer Res 1991; 51: 6110-7.
-
(1991)
Cancer Res
, vol.51
, pp. 6110-6117
-
-
Huang, P.1
Chubb, S.2
Hertel, L.W.3
Grindey, G.B.4
Plunkett, W.5
-
4
-
-
0026640498
-
Activity of 2′,2′-difluorodeoxycytidine (Gemcitabine) against human tumor colony forming units
-
Hanauske AR, Degen D, Marshall MH, Hilsenbeck SG, Grindey GB, Von Hoff DD. Activity of 2′,2′-difluorodeoxycytidine (Gemcitabine) against human tumor colony forming units. Anti-Cancer Drugs 1992; 3: 143-6.
-
(1992)
Anti-Cancer Drugs
, vol.3
, pp. 143-146
-
-
Hanauske, A.R.1
Degen, D.2
Marshall, M.H.3
Hilsenbeck, S.G.4
Grindey, G.B.5
Von Hoff, D.D.6
-
5
-
-
0026695674
-
Deoxycytidine protests normal bone marrow progenitors against ara-C and gemcitabine cytotoxicity without compromising their activity against cisplatin-resistant human ovarian cancer cells
-
Bhalla K, Holladay C, Lutzky J, et al. Deoxycytidine protests normal bone marrow progenitors against ara-C and gemcitabine cytotoxicity without compromising their activity against cisplatin-resistant human ovarian cancer cells. Gynecol Oncol 1992; 45: 32-9.
-
(1992)
Gynecol Oncol
, vol.45
, pp. 32-39
-
-
Bhalla, K.1
Holladay, C.2
Lutzky, J.3
-
6
-
-
0025325071
-
Evaluation of the antitumor activity of Gemcitabine (2′,2′-difluoro-2′-deoxycytidine)
-
Hertel LW, Boder GB, Kroin JS, et al. Evaluation of the antitumor activity of Gemcitabine (2′,2′-difluoro-2′-deoxycytidine). Cancer Res 1990; 50: 4417-22.
-
(1990)
Cancer Res
, vol.50
, pp. 4417-4422
-
-
Hertel, L.W.1
Boder, G.B.2
Kroin, J.S.3
-
7
-
-
0025295958
-
Modulatory activity of 2′,2′-difluorodeoxycytidine on phosphorylation and cytotoxicity of arabinosyl nucleosides
-
Gandhi V, Plunkett W. Modulatory activity of 2′,2′-difluorodeoxycytidine on phosphorylation and cytotoxicity of arabinosyl nucleosides. Cancer Res 1990; 50: 3675-80.
-
(1990)
Cancer Res
, vol.50
, pp. 3675-3680
-
-
Gandhi, V.1
Plunkett, W.2
-
8
-
-
0027408631
-
19F-magnetic resonance spectroscopy and cytostatic in vivo activity of gemcitabine(dFdC) in two small cell lung cancer xenografts
-
19F-magnetic resonance spectroscopy and cytostatic in vivo activity of gemcitabine(dFdC) in two small cell lung cancer xenografts. Ann Oncol 1993; 4: 157-60.
-
(1993)
Ann Oncol
, vol.4
, pp. 157-160
-
-
Kristjansen, P.E.G.1
Quistorff, B.2
Spang-Thomsen, M.3
Hansen, H.H.4
-
9
-
-
0028275406
-
Antitumor activity of LY188011, a new deoxycytidine analog against human cancers xenografted into nude mice
-
Fujita M, Fujita F, Inaba H, Taguchi T. Antitumor activity of LY188011, a new deoxycytidine analog against human cancers xenografted into nude mice. Jpn J Cancer Chemother 1994; 21: 517-23.
-
(1994)
Jpn J Cancer Chemother
, vol.21
, pp. 517-523
-
-
Fujita, M.1
Fujita, F.2
Inaba, H.3
Taguchi, T.4
-
11
-
-
0029909752
-
An early-phase II study of Gemcitabine hydrochloride
-
Fukuoka M, Noda K, K Hasegawa, et al. An early-phase II study of Gemcitabine hydrochloride. Jpn J Cancer Chemother 1996; 23: 1813-24.
-
(1996)
Jpn J Cancer Chemother
, vol.23
, pp. 1813-1824
-
-
Fukuoka, M.1
Noda, K.2
Hasegawa, K.3
-
12
-
-
0000425098
-
The Criteria of the Adverse Reaction Assessment List of Japan Society for Cancer Therapy
-
The Criteria of the Adverse Reaction Assessment List of Japan Society for Cancer Therapy. J Jpn Soc Cancer Ther 1986; 21: 943-53.
-
(1986)
J Jpn Soc Cancer Ther
, vol.21
, pp. 943-953
-
-
-
13
-
-
0028272277
-
Phase I clinical trial of gemcitabine given as an intravenous bolus on five consecutive days
-
O'Rourke TJ, Brown TD, Harvin K, et al. Phase I clinical trial of gemcitabine given as an intravenous bolus on five consecutive days. Eur J Cancer 1994; 30: 417-8.
-
(1994)
Eur J Cancer
, vol.30
, pp. 417-418
-
-
O'Rourke, T.J.1
Brown, T.D.2
Harvin, K.3
-
14
-
-
0026441565
-
Difluorodeoxycytidine (dFdC) gemcitabine: A phase I study
-
Poplin E, Corbett T, Flaherty L, et al. Difluorodeoxycytidine (dFdC) gemcitabine: a phase I study. Invest New Drugs 1992; 10: 165-70.
-
(1992)
Invest New Drugs
, vol.10
, pp. 165-170
-
-
Poplin, E.1
Corbett, T.2
Flaherty, L.3
-
15
-
-
0025978216
-
A phase I clinical plasma, and cellular pharmacology study of gemcitabine
-
Abbruzzese JL, Grunewald R, Weeks EA, et al. A phase I clinical plasma, and cellular pharmacology study of gemcitabine. J Clin Oncol 1991; 9: 491-8.
-
(1991)
J Clin Oncol
, vol.9
, pp. 491-498
-
-
Abbruzzese, J.L.1
Grunewald, R.2
Weeks, E.A.3
-
16
-
-
0028033227
-
Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: A phase II study
-
Anderson H. Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 1994; 12: 1821-6.
-
(1994)
J Clin Oncol
, vol.12
, pp. 1821-1826
-
-
Anderson, H.1
-
17
-
-
0027993707
-
Efficacy and Safety Profile of Gemcitabine in non-small-cell lung cancer: A phase II study
-
Abratt RF, Bezwoda WR, Falkson G. Hacking D. Rugg TA. Efficacy and Safety Profile of Gemcitabine in non-small-cell lung cancer: a phase II study. J Clin Oncol 1994; 12: 1535-40.
-
(1994)
J Clin Oncol
, vol.12
, pp. 1535-1540
-
-
Abratt, R.F.1
Bezwoda, W.R.2
Falkson, G.3
Hacking, D.4
Rugg, T.A.5
-
18
-
-
0028043583
-
Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) given as a twice weekly schedule to previously untreated patients with non-small cell lung cancer
-
Lund B, Ryberg M, Meidahl-Petersen P, Anderson LH. Thatcher N, Dombernowsky P. Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) given as a twice weekly schedule to previously untreated patients with non-small cell lung cancer. Ann Oncol 1994; 5: 852-3.
-
(1994)
Ann Oncol
, vol.5
, pp. 852-853
-
-
Lund, B.1
Ryberg, M.2
Meidahl-Petersen, P.3
Anderson, L.H.4
Thatcher, N.5
Dombernowsky, P.6
-
19
-
-
0031032211
-
Weekly gemcitabine (days 1, 8, 15) with monthly cisplatin (day 15): Active combination chemotherapy for advanced non-small cell lung cancer
-
Abratt RP, Bezwoda WR, Goedhals L, Hacking DJ. Weekly gemcitabine (days 1, 8, 15) with monthly cisplatin (day 15): active combination chemotherapy for advanced non-small cell lung cancer. J Clin Oncol 1997; 15: 744-9.
-
(1997)
J Clin Oncol
, vol.15
, pp. 744-749
-
-
Abratt, R.P.1
Bezwoda, W.R.2
Goedhals, L.3
Hacking, D.J.4
-
20
-
-
17344384670
-
Cisplatin-gemcitabine combination in advanced non-small cell lung cancer (NSCLC). A phase II study
-
Crinò L, Scagliotti G, Marangolo M, et al. Cisplatin-gemcitabine combination in advanced non-small cell lung cancer (NSCLC). A phase II study. J Clin Oncol 1997; 15: 297-303.
-
(1997)
J Clin Oncol
, vol.15
, pp. 297-303
-
-
Crinò, L.1
Scagliotti, G.2
Marangolo, M.3
-
21
-
-
0002188225
-
Extended survival in stage IH and IV non-small cell lung cancer (NSCLC) patients treated with gemcitabine plus monthly cisplatin
-
abstr
-
Sandier A, Crin L, Steward WP, Abratt RP Extended survival in stage IH and IV non-small cell lung cancer (NSCLC) patients treated with gemcitabine plus monthly cisplatin. Ann Oncol 1996; 7 (suppl 5, abstr 435P).
-
(1996)
Ann Oncol
, vol.7
, Issue.5 SUPPL.
-
-
Sandier, A.1
Crin, L.2
Steward, W.P.3
Abratt, R.P.4
-
22
-
-
0029963324
-
Phase I dose-escalation trial of gemcitabine and cisplatin for advanced non-small cell lung cancer: Usefulness of mathematic modelling to determine maximum tolerated dose
-
Shepherd FA. Phase I dose-escalation trial of gemcitabine and cisplatin for advanced non-small cell lung cancer: usefulness of mathematic modelling to determine maximum tolerated dose, J Clin Oncol 1996; 14: 1656-62.
-
(1996)
J Clin Oncol
, vol.14
, pp. 1656-1662
-
-
Shepherd, F.A.1
-
23
-
-
0029848166
-
Phase I/II study of gemcitabine and cisplatin in the treatment of advanced non-small cell lung cancer - Preliminary results
-
Steward WP, Dunlop DJ, Dabouis G, Lacroix H, Talbot D. Phase I/II study of gemcitabine and cisplatin in the treatment of advanced non-small cell lung cancer - preliminary results. Semin Oncol 1996; 23 (suppl 10): 43-7.
-
(1996)
Semin Oncol
, vol.23
, Issue.10 SUPPL.
, pp. 43-47
-
-
Steward, W.P.1
Dunlop, D.J.2
Dabouis, G.3
Lacroix, H.4
Talbot, D.5
-
24
-
-
0029845033
-
A phase I study of gemcitabine and carboplatin in non-small cell lung cancer (NSCLC)
-
Carmichael J, Allerheiligen S, Walling J. A phase I study of gemcitabine and carboplatin in non-small cell lung cancer (NSCLC). Semin Oncol 1996; 23 (suppl 10): 55-9.
-
(1996)
Semin Oncol
, vol.23
, Issue.10 SUPPL.
, pp. 55-59
-
-
Carmichael, J.1
Allerheiligen, S.2
Walling, J.3
-
25
-
-
0013659051
-
Phase II study of gemcitabine (GEM) and ifosfamide (IFO) in advanced non-small cell lung cancer (NSCLC)
-
abstr 1137
-
Manegold CH, Eberhard W, Wilke H, et al. Phase II study of gemcitabine (GEM) and ifosfamide (IFO) in advanced non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 1996; 15: 380 (abstr 1137).
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
, pp. 380
-
-
Manegold, C.H.1
Eberhard, W.2
Wilke, H.3
|