메뉴 건너뛰기




Volumn 8, Issue 6, 1997, Pages 574-581

Activity of gemcitabine in the treatment of patients with non-small cell lung cancer: A multicenter phase II study

Author keywords

Gemcitabine; Multicenter; NSCLC; Nucleoside analog; Phase II study

Indexed keywords

GEMCITABINE;

EID: 0030875718     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199707000-00004     Document Type: Article
Times cited : (23)

References (25)
  • 1
    • 0023935362 scopus 로고
    • Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleotides
    • Hertel LW, Kroin JS, Misner JW, et al. Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleotides. J Org Chem 1988; 53: 2406-9.
    • (1988) J Org Chem , vol.53 , pp. 2406-2409
    • Hertel, L.W.1    Kroin, J.S.2    Misner, J.W.3
  • 2
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosy cytosine
    • Heinemann V, Hertel LW, Grindey GB, Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosy cytosine. Cancer Res 1988; 48: 4024-31.
    • (1988) Cancer Res , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 5
    • 0026695674 scopus 로고
    • Deoxycytidine protests normal bone marrow progenitors against ara-C and gemcitabine cytotoxicity without compromising their activity against cisplatin-resistant human ovarian cancer cells
    • Bhalla K, Holladay C, Lutzky J, et al. Deoxycytidine protests normal bone marrow progenitors against ara-C and gemcitabine cytotoxicity without compromising their activity against cisplatin-resistant human ovarian cancer cells. Gynecol Oncol 1992; 45: 32-9.
    • (1992) Gynecol Oncol , vol.45 , pp. 32-39
    • Bhalla, K.1    Holladay, C.2    Lutzky, J.3
  • 6
    • 0025325071 scopus 로고
    • Evaluation of the antitumor activity of Gemcitabine (2′,2′-difluoro-2′-deoxycytidine)
    • Hertel LW, Boder GB, Kroin JS, et al. Evaluation of the antitumor activity of Gemcitabine (2′,2′-difluoro-2′-deoxycytidine). Cancer Res 1990; 50: 4417-22.
    • (1990) Cancer Res , vol.50 , pp. 4417-4422
    • Hertel, L.W.1    Boder, G.B.2    Kroin, J.S.3
  • 7
    • 0025295958 scopus 로고
    • Modulatory activity of 2′,2′-difluorodeoxycytidine on phosphorylation and cytotoxicity of arabinosyl nucleosides
    • Gandhi V, Plunkett W. Modulatory activity of 2′,2′-difluorodeoxycytidine on phosphorylation and cytotoxicity of arabinosyl nucleosides. Cancer Res 1990; 50: 3675-80.
    • (1990) Cancer Res , vol.50 , pp. 3675-3680
    • Gandhi, V.1    Plunkett, W.2
  • 8
    • 0027408631 scopus 로고
    • 19F-magnetic resonance spectroscopy and cytostatic in vivo activity of gemcitabine(dFdC) in two small cell lung cancer xenografts
    • 19F-magnetic resonance spectroscopy and cytostatic in vivo activity of gemcitabine(dFdC) in two small cell lung cancer xenografts. Ann Oncol 1993; 4: 157-60.
    • (1993) Ann Oncol , vol.4 , pp. 157-160
    • Kristjansen, P.E.G.1    Quistorff, B.2    Spang-Thomsen, M.3    Hansen, H.H.4
  • 9
    • 0028275406 scopus 로고
    • Antitumor activity of LY188011, a new deoxycytidine analog against human cancers xenografted into nude mice
    • Fujita M, Fujita F, Inaba H, Taguchi T. Antitumor activity of LY188011, a new deoxycytidine analog against human cancers xenografted into nude mice. Jpn J Cancer Chemother 1994; 21: 517-23.
    • (1994) Jpn J Cancer Chemother , vol.21 , pp. 517-523
    • Fujita, M.1    Fujita, F.2    Inaba, H.3    Taguchi, T.4
  • 11
    • 0029909752 scopus 로고    scopus 로고
    • An early-phase II study of Gemcitabine hydrochloride
    • Fukuoka M, Noda K, K Hasegawa, et al. An early-phase II study of Gemcitabine hydrochloride. Jpn J Cancer Chemother 1996; 23: 1813-24.
    • (1996) Jpn J Cancer Chemother , vol.23 , pp. 1813-1824
    • Fukuoka, M.1    Noda, K.2    Hasegawa, K.3
  • 12
    • 0000425098 scopus 로고
    • The Criteria of the Adverse Reaction Assessment List of Japan Society for Cancer Therapy
    • The Criteria of the Adverse Reaction Assessment List of Japan Society for Cancer Therapy. J Jpn Soc Cancer Ther 1986; 21: 943-53.
    • (1986) J Jpn Soc Cancer Ther , vol.21 , pp. 943-953
  • 13
    • 0028272277 scopus 로고
    • Phase I clinical trial of gemcitabine given as an intravenous bolus on five consecutive days
    • O'Rourke TJ, Brown TD, Harvin K, et al. Phase I clinical trial of gemcitabine given as an intravenous bolus on five consecutive days. Eur J Cancer 1994; 30: 417-8.
    • (1994) Eur J Cancer , vol.30 , pp. 417-418
    • O'Rourke, T.J.1    Brown, T.D.2    Harvin, K.3
  • 14
    • 0026441565 scopus 로고
    • Difluorodeoxycytidine (dFdC) gemcitabine: A phase I study
    • Poplin E, Corbett T, Flaherty L, et al. Difluorodeoxycytidine (dFdC) gemcitabine: a phase I study. Invest New Drugs 1992; 10: 165-70.
    • (1992) Invest New Drugs , vol.10 , pp. 165-170
    • Poplin, E.1    Corbett, T.2    Flaherty, L.3
  • 15
    • 0025978216 scopus 로고
    • A phase I clinical plasma, and cellular pharmacology study of gemcitabine
    • Abbruzzese JL, Grunewald R, Weeks EA, et al. A phase I clinical plasma, and cellular pharmacology study of gemcitabine. J Clin Oncol 1991; 9: 491-8.
    • (1991) J Clin Oncol , vol.9 , pp. 491-498
    • Abbruzzese, J.L.1    Grunewald, R.2    Weeks, E.A.3
  • 16
    • 0028033227 scopus 로고
    • Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: A phase II study
    • Anderson H. Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 1994; 12: 1821-6.
    • (1994) J Clin Oncol , vol.12 , pp. 1821-1826
    • Anderson, H.1
  • 17
    • 0027993707 scopus 로고
    • Efficacy and Safety Profile of Gemcitabine in non-small-cell lung cancer: A phase II study
    • Abratt RF, Bezwoda WR, Falkson G. Hacking D. Rugg TA. Efficacy and Safety Profile of Gemcitabine in non-small-cell lung cancer: a phase II study. J Clin Oncol 1994; 12: 1535-40.
    • (1994) J Clin Oncol , vol.12 , pp. 1535-1540
    • Abratt, R.F.1    Bezwoda, W.R.2    Falkson, G.3    Hacking, D.4    Rugg, T.A.5
  • 18
    • 0028043583 scopus 로고
    • Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) given as a twice weekly schedule to previously untreated patients with non-small cell lung cancer
    • Lund B, Ryberg M, Meidahl-Petersen P, Anderson LH. Thatcher N, Dombernowsky P. Phase II study of gemcitabine (2′,2′-difluorodeoxycytidine) given as a twice weekly schedule to previously untreated patients with non-small cell lung cancer. Ann Oncol 1994; 5: 852-3.
    • (1994) Ann Oncol , vol.5 , pp. 852-853
    • Lund, B.1    Ryberg, M.2    Meidahl-Petersen, P.3    Anderson, L.H.4    Thatcher, N.5    Dombernowsky, P.6
  • 19
    • 0031032211 scopus 로고    scopus 로고
    • Weekly gemcitabine (days 1, 8, 15) with monthly cisplatin (day 15): Active combination chemotherapy for advanced non-small cell lung cancer
    • Abratt RP, Bezwoda WR, Goedhals L, Hacking DJ. Weekly gemcitabine (days 1, 8, 15) with monthly cisplatin (day 15): active combination chemotherapy for advanced non-small cell lung cancer. J Clin Oncol 1997; 15: 744-9.
    • (1997) J Clin Oncol , vol.15 , pp. 744-749
    • Abratt, R.P.1    Bezwoda, W.R.2    Goedhals, L.3    Hacking, D.J.4
  • 20
    • 17344384670 scopus 로고    scopus 로고
    • Cisplatin-gemcitabine combination in advanced non-small cell lung cancer (NSCLC). A phase II study
    • Crinò L, Scagliotti G, Marangolo M, et al. Cisplatin-gemcitabine combination in advanced non-small cell lung cancer (NSCLC). A phase II study. J Clin Oncol 1997; 15: 297-303.
    • (1997) J Clin Oncol , vol.15 , pp. 297-303
    • Crinò, L.1    Scagliotti, G.2    Marangolo, M.3
  • 21
    • 0002188225 scopus 로고    scopus 로고
    • Extended survival in stage IH and IV non-small cell lung cancer (NSCLC) patients treated with gemcitabine plus monthly cisplatin
    • abstr
    • Sandier A, Crin L, Steward WP, Abratt RP Extended survival in stage IH and IV non-small cell lung cancer (NSCLC) patients treated with gemcitabine plus monthly cisplatin. Ann Oncol 1996; 7 (suppl 5, abstr 435P).
    • (1996) Ann Oncol , vol.7 , Issue.5 SUPPL.
    • Sandier, A.1    Crin, L.2    Steward, W.P.3    Abratt, R.P.4
  • 22
    • 0029963324 scopus 로고    scopus 로고
    • Phase I dose-escalation trial of gemcitabine and cisplatin for advanced non-small cell lung cancer: Usefulness of mathematic modelling to determine maximum tolerated dose
    • Shepherd FA. Phase I dose-escalation trial of gemcitabine and cisplatin for advanced non-small cell lung cancer: usefulness of mathematic modelling to determine maximum tolerated dose, J Clin Oncol 1996; 14: 1656-62.
    • (1996) J Clin Oncol , vol.14 , pp. 1656-1662
    • Shepherd, F.A.1
  • 23
    • 0029848166 scopus 로고    scopus 로고
    • Phase I/II study of gemcitabine and cisplatin in the treatment of advanced non-small cell lung cancer - Preliminary results
    • Steward WP, Dunlop DJ, Dabouis G, Lacroix H, Talbot D. Phase I/II study of gemcitabine and cisplatin in the treatment of advanced non-small cell lung cancer - preliminary results. Semin Oncol 1996; 23 (suppl 10): 43-7.
    • (1996) Semin Oncol , vol.23 , Issue.10 SUPPL. , pp. 43-47
    • Steward, W.P.1    Dunlop, D.J.2    Dabouis, G.3    Lacroix, H.4    Talbot, D.5
  • 24
    • 0029845033 scopus 로고    scopus 로고
    • A phase I study of gemcitabine and carboplatin in non-small cell lung cancer (NSCLC)
    • Carmichael J, Allerheiligen S, Walling J. A phase I study of gemcitabine and carboplatin in non-small cell lung cancer (NSCLC). Semin Oncol 1996; 23 (suppl 10): 55-9.
    • (1996) Semin Oncol , vol.23 , Issue.10 SUPPL. , pp. 55-59
    • Carmichael, J.1    Allerheiligen, S.2    Walling, J.3
  • 25
    • 0013659051 scopus 로고    scopus 로고
    • Phase II study of gemcitabine (GEM) and ifosfamide (IFO) in advanced non-small cell lung cancer (NSCLC)
    • abstr 1137
    • Manegold CH, Eberhard W, Wilke H, et al. Phase II study of gemcitabine (GEM) and ifosfamide (IFO) in advanced non-small cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 1996; 15: 380 (abstr 1137).
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 380
    • Manegold, C.H.1    Eberhard, W.2    Wilke, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.