-
1
-
-
0025674177
-
Detection of a specific mitochondrial DNA deletion in tissues of older humans
-
Cortopassi G.A., Arnheim N. Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Res. 18:1990;6927-6933.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6927-6933
-
-
Cortopassi, G.A.1
Arnheim, N.2
-
2
-
-
0027017232
-
Mitochondrial DNA deletions in human brain: Regional variability and increase with advanced age
-
Corral-Debrinski M., Horton T., Lott M.T., Shoffner J.M., Beal M.F., Wallace D.C. Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nature Genet. 2:1992;324-329.
-
(1992)
Nature Genet.
, vol.2
, pp. 324-329
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
Beal, M.F.5
Wallace, D.C.6
-
3
-
-
0024328462
-
Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome
-
Moraes C.T., DiMauro S., Zeviani M., Lombes A., Shanske S., Miranda A.F., Nakase H., Bonilla E., Werneck L.C., Servidei S., Nonaka I., Koga Y., Spiro A., Brownell K.W., Schmidt B., Schotland D.L., Zupanc M.D., DeVivo D.C., Schon E.A., Rowland L.P. Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome. New Engl. J. Med. 320:1989;1293-1299.
-
(1989)
New Engl. J. Med.
, vol.320
, pp. 1293-1299
-
-
Moraes, C.T.1
DiMauro, S.2
Zeviani, M.3
Lombes, A.4
Shanske, S.5
Miranda, A.F.6
Nakase, H.7
Bonilla, E.8
Werneck, L.C.9
Servidei, S.10
Nonaka, I.11
Koga, Y.12
Spiro, A.13
Brownell, K.W.14
Schmidt, B.15
Schotland, D.L.16
Zupanc, M.D.17
Devivo, D.C.18
Schon, E.A.19
Rowland, L.P.20
more..
-
4
-
-
0024596946
-
A direct repeat is a hotspot for large-scale deletions of human mitochondrial DNA
-
Schon E.A., Rizzuto R., Moraes C.T., Nakase H., Zeviani M., DiMauro S. A direct repeat is a hotspot for large-scale deletions of human mitochondrial DNA. Science. 244:1989;346-349.
-
(1989)
Science
, vol.244
, pp. 346-349
-
-
Schon, E.A.1
Rizzuto, R.2
Moraes, C.T.3
Nakase, H.4
Zeviani, M.5
DiMauro, S.6
-
5
-
-
0026860988
-
Aging-associated deletions of human diaphragmatic mitochondrial DNA
-
Torii K., Sugiyama S., Tanaka M., Takagi K., Hanaki Y., Iida K.-I., Matsuyama M., Hirabayashi N., Uno Y., Ozawa T. Aging-associated deletions of human diaphragmatic mitochondrial DNA. Am. J. Resp. Cell Mol. Biol. 6:1992;543-549.
-
(1992)
Am. J. Resp. Cell Mol. Biol.
, vol.6
, pp. 543-549
-
-
Torii, K.1
Sugiyama, S.2
Tanaka, M.3
Takagi, K.4
Hanaki, Y.5
Iida, K.-I.6
Matsuyama, M.7
Hirabayashi, N.8
Uno, Y.9
Ozawa, T.10
-
6
-
-
0028349234
-
Differential accumulations of 4977 bp deletion in mitochondrial DNA of various tissues in human ageing
-
Lee H.-C., Pang C.-Y., Hsu H.-S., Wei Y.-H. Differential accumulations of 4977 bp deletion in mitochondrial DNA of various tissues in human ageing. Biochim. Biophys. Acta. 122:1994;37-43.
-
(1994)
Biochim. Biophys. Acta
, vol.122
, pp. 37-43
-
-
Lee, H.-C.1
Pang, C.-Y.2
Hsu, H.-S.3
Wei, Y.-H.4
-
7
-
-
0027021442
-
Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
-
Soong N.W., Hinton D.R., Cortopassi G., Arnheim N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nature Genet. 2:1992;318-323.
-
(1992)
Nature Genet.
, vol.2
, pp. 318-323
-
-
Soong, N.W.1
Hinton, D.R.2
Cortopassi, G.3
Arnheim, N.4
-
9
-
-
0026775958
-
Free radical theory of aging
-
Harman D. Free radical theory of aging. Mutation Res. 275:1992;257-266.
-
(1992)
Mutation Res.
, vol.275
, pp. 257-266
-
-
Harman, D.1
-
10
-
-
0019978703
-
Replication of animal mitochondrial DNA
-
Clayton D.A. Replication of animal mitochondrial DNA. Cell. 28:1982;693-705.
-
(1982)
Cell
, vol.28
, pp. 693-705
-
-
Clayton, D.A.1
-
11
-
-
0027527023
-
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
-
Mecocci P., MacGarvey U., Kaufman A.E., Koontz D., Shoffner J.M., Wallace D.C., Beal M.F. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann. Neurol. 34:1993;609-616.
-
(1993)
Ann. Neurol.
, vol.34
, pp. 609-616
-
-
Mecocci, P.1
MacGarvey, U.2
Kaufman, A.E.3
Koontz, D.4
Shoffner, J.M.5
Wallace, D.C.6
Beal, M.F.7
-
12
-
-
0025309791
-
Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging?
-
Bandy B., Davison A.J. Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radic. Biol. Med. 8:1990;523-539.
-
(1990)
Free Radic. Biol. Med.
, vol.8
, pp. 523-539
-
-
Bandy, B.1
Davison, A.J.2
-
13
-
-
0027235532
-
Aging, cytochrome oxidase activity, and hydrogen peroxide release by mitochondria
-
Sohal R.S. Aging, cytochrome oxidase activity, and hydrogen peroxide release by mitochondria. Free Radic. Biol. Med. 14:1993;583-588.
-
(1993)
Free Radic. Biol. Med.
, vol.14
, pp. 583-588
-
-
Sohal, R.S.1
-
14
-
-
0025948247
-
Age-associated accumulation of 8-hydroxyguanosine in mitochondrial DNA of human diafragm
-
Hayakawa M., Torii K., Sugyama S., Tanaka M., Ozawa T. Age-associated accumulation of 8-hydroxyguanosine in mitochondrial DNA of human diafragm. Biochem. Biophys. Res. Commun. 179:1991;1023-1029.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.179
, pp. 1023-1029
-
-
Hayakawa, M.1
Torii, K.2
Sugyama, S.3
Tanaka, M.4
Ozawa, T.5
-
15
-
-
0002543513
-
Mitochondrial DNA mutation and human aging: molecular biology, bioenergetics, and redox therapy
-
in: S. DiMauro and D.C. Wallace (Eds.) Raven Press, New York
-
Nagley, P., C. Zhang, R.D. Martinus, F. Vaillant and A.W. Linnane (1993) Mitochondrial DNA mutation and human aging: molecular biology, bioenergetics, and redox therapy, in: S. DiMauro and D.C. Wallace (Eds.), Mitochondrial DNA in Human Pathology, Raven Press, New York, pp. 137-158.
-
(1993)
Mitochondrial DNA in Human Pathology
, pp. 137-158
-
-
Nagley, P.1
Zhang, C.2
Martinus, R.D.3
Vaillant, F.4
Linnane, A.W.5
-
16
-
-
0027145131
-
Leu(UUR) gene an etiologic hotspot?
-
Leu(UUR) gene an etiologic hotspot? J. Clin. Invest. 92:1993;2906-2915.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 2906-2915
-
-
Moraes, C.T.1
Ciacci, F.2
Bonilla, E.3
Jansen, C.4
Hirano, M.5
Rao, N.6
Lovelace, R.E.7
Rowland, L.P.8
Schon, E.A.9
DiMauro, S.10
-
17
-
-
0029029469
-
Mitochondrial DNA (mtDNA) diseases: Correlation of genotype to phenotype
-
Morgan-Hughes J.A., Sweeney M.G., Cooper J.M., Hammans S.R., Brockington M., Schapira A.H.V., Harding A.E., Clark J.B. Mitochondrial DNA (mtDNA) diseases: correlation of genotype to phenotype. Biochim. Biophys. Acta. 1271:1995;135-140.
-
(1995)
Biochim. Biophys. Acta
, vol.1271
, pp. 135-140
-
-
Morgan-Hughes, J.A.1
Sweeney, M.G.2
Cooper, J.M.3
Hammans, S.R.4
Brockington, M.5
Schapira, A.H.V.6
Harding, A.E.7
Clark, J.B.8
-
18
-
-
0002439705
-
Cytochrome oxidase deficiency: Progress and problems
-
in: A.H.V. Schapira and S. DiMauro (Eds.) Butterworth-Heinemann, Oxford
-
DiMauro, S., M. Hirano, E. Bonilla, C.T. Moraes and E.A. Schon (1994) Cytochrome oxidase deficiency: progress and problems, in: A.H.V. Schapira and S. DiMauro (Eds.), Mitochondrial Disorders in Neurology, Butterworth-Heinemann, Oxford, pp. 91-115.
-
(1994)
Mitochondrial Disorders in Neurology
, pp. 91-115
-
-
DiMauro, S.1
Hirano, M.2
Bonilla, E.3
Moraes, C.T.4
Schon, E.A.5
-
19
-
-
0023883150
-
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
-
Holt I.J., Harding A.E., Morgan Hughes J.A. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature. 331:1988;717-719.
-
(1988)
Nature
, vol.331
, pp. 717-719
-
-
Holt, I.J.1
Harding, A.E.2
Morgan Hughes, J.A.3
-
20
-
-
0024601360
-
An autossomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region
-
Zeviani M., Servidei S., Gellera C., Bertini E., DiMauro S., DiDonato S. An autossomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region. Nature. 339:1989;309-311.
-
(1989)
Nature
, vol.339
, pp. 309-311
-
-
Zeviani, M.1
Servidei, S.2
Gellera, C.3
Bertini, E.4
DiMauro, S.5
Didonato, S.6
-
21
-
-
0025666322
-
Leu (UUR) gene associated with the MELAS subgroup of mitochondrial encephalopathies
-
Leu (UUR) gene associated with the MELAS subgroup of mitochondrial encephalopathies. Nature. 348:1990;651-653.
-
(1990)
Nature
, vol.348
, pp. 651-653
-
-
Goto, Y.1
Nonaka, I.2
Horai, S.3
-
22
-
-
0027865639
-
Lys gene
-
Lys gene. Eur. J. Hum. Genet. 1:1993;80-87.
-
(1993)
Eur. J. Hum. Genet.
, vol.1
, pp. 80-87
-
-
Zeviani, M.1
Muntoni, F.2
Savarese, N.3
Serra, G.4
Tiranti, V.5
Carrara, F.6
Mariotti, C.7
Didonato, S.8
-
23
-
-
0028927272
-
Segregation patterns of a novel mutation in the mitochondrial tRNA glutamic acid gene associated with myopathy and diabetes mellitus
-
Hao H., Bonilla E., Manfredi G., DiMauro S., Moraes C.T. Segregation patterns of a novel mutation in the mitochondrial tRNA glutamic acid gene associated with myopathy and diabetes mellitus. Am. J. Hum. Genet. 56:1995;1017-1025.
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 1017-1025
-
-
Hao, H.1
Bonilla, E.2
Manfredi, G.3
DiMauro, S.4
Moraes, C.T.5
-
24
-
-
0026074885
-
Hypoxemia is associated with mitochondrial DNA damage and gene induction
-
Corral-Debrinski M., Stepien G., Shoffner J.M., Lott M.T., Kanter K., Wallace D.C. Hypoxemia is associated with mitochondrial DNA damage and gene induction. J. Am. Med. Assoc. 266:1991;1812-1816.
-
(1991)
J. Am. Med. Assoc.
, vol.266
, pp. 1812-1816
-
-
Corral-Debrinski, M.1
Stepien, G.2
Shoffner, J.M.3
Lott, M.T.4
Kanter, K.5
Wallace, D.C.6
-
25
-
-
0027431450
-
Respiratory chain and mitochondrial DNA in muscle and brain in Parkinson's disease patients
-
DiDonato S., Zeviani M., Giovannini P., Savarese N., Rimoldi M., Mariotti C., Girotti F., Caraceni T. Respiratory chain and mitochondrial DNA in muscle and brain in Parkinson's disease patients. Neurology. 43:1993;2262-2268.
-
(1993)
Neurology
, vol.43
, pp. 2262-2268
-
-
Didonato, S.1
Zeviani, M.2
Giovannini, P.3
Savarese, N.4
Rimoldi, M.5
Mariotti, C.6
Girotti, F.7
Caraceni, T.8
-
27
-
-
0026718556
-
Leu(UUR) mutation in MELAS: Genetic, biochemical, and morphological correlations in skeletal muscle
-
Leu(UUR) mutation in MELAS: genetic, biochemical, and morphological correlations in skeletal muscle. Am. J. Hum. Genet. 50:1992;934-949.
-
(1992)
Am. J. Hum. Genet.
, vol.50
, pp. 934-949
-
-
Moraes, C.T.1
Ricci, E.2
Bonilla, E.3
DiMauro, S.4
Schon, E.A.5
-
28
-
-
0026907560
-
Molecular analysis of the muscle pathology associated with mitochondrial DNA deletions
-
Moraes C.T., Ricci E., Petruzzella V., Shanske S., DiMauro S., Schon E.A., Bonilla E. Molecular analysis of the muscle pathology associated with mitochondrial DNA deletions. Nature Genet. 1:1992;359-367.
-
(1992)
Nature Genet.
, vol.1
, pp. 359-367
-
-
Moraes, C.T.1
Ricci, E.2
Petruzzella, V.3
Shanske, S.4
DiMauro, S.5
Schon, E.A.6
Bonilla, E.7
-
30
-
-
0025943770
-
Hydrogen peroxide production by mitochondria may be a biomarker of aging
-
Sohal (1991) Hydrogen peroxide production by mitochondria may be a biomarker of aging, Mech. Ageing Dev., 60, 189-198.
-
(1991)
Mech. Ageing Dev.
, vol.60
, pp. 189-198
-
-
Sohal1
-
31
-
-
0024580556
-
Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in aging
-
Trounce I., Byrne E., Marzuki S. Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in aging. Lancet. 1:1989;637-639.
-
(1989)
Lancet
, vol.1
, pp. 637-639
-
-
Trounce, I.1
Byrne, E.2
Marzuki, S.3
-
32
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
Cooper J.M., Mann V.M., Schapira A.H.V. Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing. J. Neurol. Sci. 113:1992;91-98.
-
(1992)
J. Neurol. Sci.
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.V.3
-
33
-
-
0028294612
-
Impairment of mitochondrial oxidative phosphorylation in the brain of aged mice
-
Ferrándiz M.L., Martínez M., DeJuan E., Díez A., Bustos F., Miquel J. Impairment of mitochondrial oxidative phosphorylation in the brain of aged mice. Brain Res. 644:1994;335-338.
-
(1994)
Brain Res.
, vol.644
, pp. 335-338
-
-
Ferrándiz, M.L.1
Martínez, M.2
Dejuan, E.3
Díez, A.4
Bustos, F.5
Miquel, J.6
-
34
-
-
0026732706
-
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues
-
Cortopassi G., Shibata D., Soong N., Arnheim N. A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc. Natl. Acad. Sci. USA. 89:1992;7370-7374.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7370-7374
-
-
Cortopassi, G.1
Shibata, D.2
Soong, N.3
Arnheim, N.4
-
35
-
-
0029019593
-
Mitochondrial DNA deletions in muscle fibers in inclusion body myositis
-
Oldfors A., Moslemi A.-R., Fyhr I.-M., Holme E., Larsson N.-G., Lindberg C. Mitochondrial DNA deletions in muscle fibers in inclusion body myositis. J. Neuropathol. Exp. Neurol. 54:1995;581-587.
-
(1995)
J. Neuropathol. Exp. Neurol.
, vol.54
, pp. 581-587
-
-
Oldfors, A.1
Moslemi, A.-R.2
Fyhr, I.-M.3
Holme, E.4
Larsson, N.-G.5
Lindberg, C.6
-
36
-
-
0028942037
-
Late-onset mitochondrial myopathy
-
Johnston W., Karpati G., Carpenter S., Arnold D., Shoubridge E.A. Late-onset mitochondrial myopathy. Ann. Neurol. 37:1995;16-23.
-
(1995)
Ann. Neurol.
, vol.37
, pp. 16-23
-
-
Johnston, W.1
Karpati, G.2
Carpenter, S.3
Arnold, D.4
Shoubridge, E.A.5
-
37
-
-
0029741431
-
Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging
-
Pallotti F., Chen X., Bonilla E., Schon E.A. Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging. Am. J. Hum. Genet. 59:1996;591-602.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 591-602
-
-
Pallotti, F.1
Chen, X.2
Bonilla, E.3
Schon, E.A.4
-
38
-
-
0029059278
-
Rearranged mitochondrial genomes are present in human oocytes
-
Chen X., Prosser R., Simonetti S., Sadlock J., Jagiello G., Schon E.A. Rearranged mitochondrial genomes are present in human oocytes. Am. J. Hum. Genet. 57:1995;224-226.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 224-226
-
-
Chen, X.1
Prosser, R.2
Simonetti, S.3
Sadlock, J.4
Jagiello, G.5
Schon, E.A.6
-
40
-
-
0029816795
-
Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA
-
Jenuth J.P., Peterson A.C., Fu K., Shoubridge E.A. Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA. Nature Genet. 13:1996;146-151.
-
(1996)
Nature Genet.
, vol.13
, pp. 146-151
-
-
Jenuth, J.P.1
Peterson, A.C.2
Fu, K.3
Shoubridge, E.A.4
-
41
-
-
0000278613
-
Accumulation of mitochondrial DNA mutation in normal aging brain and muscle
-
in: S. DiMauro and D.C. Wallace (Eds.) Raven Press, New York
-
Cortopassi, G. and N. Arnheim (1993) Accumulation of mitochondrial DNA mutation in normal aging brain and muscle, in: S. DiMauro and D.C. Wallace (Eds.), Mitochondrial DNA in Human Pathology, Raven Press, New York.
-
(1993)
Mitochondrial DNA in Human Pathology
-
-
Cortopassi, G.1
Arnheim, N.2
-
42
-
-
0027476395
-
The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages
-
Munscher C., Rieger T., Müller-Höcker J., Kadenbach B. The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages. FEBS Lett. 317:1993;27-30.
-
(1993)
FEBS Lett.
, vol.317
, pp. 27-30
-
-
Munscher, C.1
Rieger, T.2
Müller-Höcker, J.3
Kadenbach, B.4
-
43
-
-
0029101232
-
Human aging is associated with stochastic somatic mutations of mitochondrial DNA
-
Kadenbach B., Münscher C., Frank V., Müller-Höcker J., Napiwotzki J. Human aging is associated with stochastic somatic mutations of mitochondrial DNA. Mutation Res. 338:1995;161-172.
-
(1995)
Mutation Res.
, vol.338
, pp. 161-172
-
-
Kadenbach, B.1
Münscher, C.2
Frank, V.3
Müller-Höcker, J.4
Napiwotzki, J.5
-
44
-
-
0028787717
-
Marked increase in the number and variety of mitochondrial DNA rearrangement in aging human skeletal muscle
-
Melov S.J.M., Kaufman A., Wallace D.C. Marked increase in the number and variety of mitochondrial DNA rearrangement in aging human skeletal muscle. Nucleic Acids Res. 23:1995;4122-4126.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4122-4126
-
-
Melov, S.J.M.1
Kaufman, A.2
Wallace, D.C.3
|