-
1
-
-
0027223897
-
Clinical pharmacokinetics of drug in obesity, an update
-
Cheymol G. Clinical pharmacokinetics of drug in obesity, an update. Clin Pharmacokin 1993; 25: 103-114.
-
(1993)
Clin Pharmacokin
, vol.25
, pp. 103-114
-
-
Cheymol, G.1
-
2
-
-
0022532554
-
Drug disposition in obese humans. An update
-
Abernethy DR. Drug disposition in obese humans. An update. Clin Pharmacokin 1986; 11: 199-213.
-
(1986)
Clin Pharmacokin
, vol.11
, pp. 199-213
-
-
Abernethy, D.R.1
-
3
-
-
0025179933
-
Comparison of propranolol and sotalol pharmacokinetics in obese subjects
-
Poirier JM, Le Jeune C, Cheymol G, Cohen A, Barré J, Hugues FC. Comparison of propranolol and sotalol pharmacokinetics in obese subjects. J Pharm Pharmacol 1990; 42: 344-348.
-
(1990)
J Pharm Pharmacol
, vol.42
, pp. 344-348
-
-
Poirier, J.M.1
Le Jeune, C.2
Cheymol, G.3
Cohen, A.4
Barré, J.5
Hugues, F.C.6
-
4
-
-
0023471843
-
Comparative pharmacokinetics of intravenous propranolol in obese and normal volunteers
-
Cheymol G, Poirier JM, Barré J, Pradalier A, Dry J. Comparative pharmacokinetics of intravenous propranolol in obese and normal volunteers. J Clin Pharmacol 1987; 27: 874-879.
-
(1987)
J Clin Pharmacol
, vol.27
, pp. 874-879
-
-
Cheymol, G.1
Poirier, J.M.2
Barré, J.3
Pradalier, A.4
Dry, J.5
-
5
-
-
0025824517
-
Pharmacokinetics of i. v. bisoprolol in obese and non obese volunteers
-
Le Jeune C, Poirier JM, Cheymol G, Ertzbischoff O, Engel F, Hugues FC. Pharmacokinetics of i. v. bisoprolol in obese and non obese volunteers. Eur J Clin Pharmacol 1991; 41: 171-174.
-
(1991)
Eur J Clin Pharmacol
, vol.41
, pp. 171-174
-
-
Le Jeune, C.1
Poirier, J.M.2
Cheymol, G.3
Ertzbischoff, O.4
Engel, F.5
Hugues, F.C.6
-
6
-
-
0024390307
-
Labetalol. A reappraisal of its pharmacology, pharmacokinetics and therapeutic use in hypertension and ischaemic heart disease
-
Goa KL, Benfield P, Sarkin EM. Labetalol. A reappraisal of its pharmacology, pharmacokinetics and therapeutic use in hypertension and ischaemic heart disease. Drugs 1989; 37: 583-627.
-
(1989)
Drugs
, vol.37
, pp. 583-627
-
-
Goa, K.L.1
Benfield, P.2
Sarkin, E.M.3
-
7
-
-
0026318643
-
Clinical pharmacology of nebivolol
-
McLay JS, Irvine N, McDevitt DG. Clinical pharmacology of nebivolol. Drug Investig 1991, 3, (Suppl. 1): 31-32.
-
(1991)
Drug Investig
, vol.3
, Issue.1 SUPPL.
, pp. 31-32
-
-
McLay, J.S.1
Irvine, N.2
McDevitt, D.G.3
-
8
-
-
8544220848
-
Weights of insured persons in the United States associated with lowest mortality
-
November-December
-
Anonymous. Weights of insured persons in the United States associated with lowest mortality. Stat Bull Metrop Insur 1989, Co40 November-December.
-
(1989)
Stat Bull Metrop Insur
, vol.CO40
-
-
-
10
-
-
0019951658
-
An automated h.p.l.c. method for the assay of propranolol and its basic metabolites in plasma and urine
-
Lo M, Silber B, Riegelman S. An automated h.p.l.c. method for the assay of propranolol and its basic metabolites in plasma and urine. J Chromatogr 1982; 20: 126-131.
-
(1982)
J Chromatogr
, vol.20
, pp. 126-131
-
-
Lo, M.1
Silber, B.2
Riegelman, S.3
-
11
-
-
8044261786
-
HPLC-fluorescence method for the determination of a new β1 adrenoreceptor blocking agent nebivolol in human plasma
-
eds. Reid E, Wilson ID, New York: Plenum Press
-
Woestenborghs R, Embrechts L, Heykants J. HPLC-fluorescence method for the determination of a new β1 adrenoreceptor blocking agent nebivolol in human plasma. In: Methodological Surveys in Biochemistry and Analysis, eds. Reid E, Wilson ID, New York: Plenum Press 1988; Vol 18: 215-216.
-
(1988)
Methodological Surveys in Biochemistry and Analysis
, vol.18
, pp. 215-216
-
-
Woestenborghs, R.1
Embrechts, L.2
Heykants, J.3
-
12
-
-
0019776770
-
The determination of labetalol in plasma by high-performance liquid chromatography using fluorescence detection
-
Meredith PA, McSharry D, Elliot HL, Reid JL. The determination of labetalol in plasma by high-performance liquid chromatography using fluorescence detection. J Pharmacol Methods 1981; 6: 309-314.
-
(1981)
J Pharmacol Methods
, vol.6
, pp. 309-314
-
-
Meredith, P.A.1
McSharry, D.2
Elliot, H.L.3
Reid, J.L.4
-
13
-
-
0026344726
-
Clinical pharmacokinetics of nebivolol. A review
-
Van Peer A, Snoeck E, Woestenborghs CR, et al. Clinical pharmacokinetics of nebivolol. A review. Drug Investig 1991; 3 (Suppl. 1): 25-30.
-
(1991)
Drug Investig
, vol.3
, Issue.1 SUPPL.
, pp. 25-30
-
-
Van Peer, A.1
Snoeck, E.2
Woestenborghs, C.R.3
-
14
-
-
0024565089
-
Determination of dextromethorphan metabolizer phenotype in healthy volunteers
-
Hildebrand M, Seifert W, Reichenberger A. Determination of dextromethorphan metabolizer phenotype in healthy volunteers. Eur J Clin Pharmacol 1989; 36: 315-318.
-
(1989)
Eur J Clin Pharmacol
, vol.36
, pp. 315-318
-
-
Hildebrand, M.1
Seifert, W.2
Reichenberger, A.3
-
15
-
-
0021286079
-
Pharm: An interactive graphic program for individual and population pharmacokinetic parameter population
-
Gomeni R. Pharm: an interactive graphic program for individual and population pharmacokinetic parameter population. Comp Biol Med 1984; 14: 25-34.
-
(1984)
Comp Biol Med
, vol.14
, pp. 25-34
-
-
Gomeni, R.1
-
16
-
-
0027071736
-
pH-metric log P. Part 1. Difference plots for determining ion-pair octanol-water partition coefficients of multiprotic substances
-
Avdeef A. pH-metric log P. Part 1. Difference plots for determining ion-pair octanol-water partition coefficients of multiprotic substances. Quant Struct - Act Relat 1992; 11: 510-517.
-
(1992)
Quant Struct - Act Relat
, vol.11
, pp. 510-517
-
-
Avdeef, A.1
-
17
-
-
0027245634
-
pH-metric log P. II. Refinement of partition coefficients and ionization constants of multiprotic substances
-
Avdeef A. pH-metric log P. II. Refinement of partition coefficients and ionization constants of multiprotic substances. J Pharm Sci 1993; 82: 1-8.
-
(1993)
J Pharm Sci
, vol.82
, pp. 1-8
-
-
Avdeef, A.1
-
18
-
-
0344377795
-
Measurement of partition coefficients using centrifugal partition chromatography: Method development and application to the determination of solute structural properties
-
Conway, WD, Petroski, PJ Eds.; American Chemical Society, Washington, DC, USA
-
Tsai RS, Carrupt PA, Testa B. Measurement of partition coefficients using centrifugal partition chromatography: method development and application to the determination of solute structural properties. In ACS Symposium Series no. 593. Modeen contercurrent Chromatography, Conway, WD, Petroski, PJ Eds.; American Chemical Society, Washington, DC, USA: 1995: 143-154
-
(1995)
ACS Symposium Series No. 593. Modeen Contercurrent Chromatography
, pp. 143-154
-
-
Tsai, R.S.1
Carrupt, P.A.2
Testa, B.3
-
19
-
-
0029098481
-
Structure-lipophilicity and structure-polarity relationships of amino acids and peptides
-
Vallat P, Gaillard P, Carrupt PA, Tsai RS, Testa B. Structure-lipophilicity and structure-polarity relationships of amino acids and peptides. Helv Chim Acta 1995; 78: 471-485.
-
(1995)
Helv Chim Acta
, vol.78
, pp. 471-485
-
-
Vallat, P.1
Gaillard, P.2
Carrupt, P.A.3
Tsai, R.S.4
Testa, B.5
-
20
-
-
0001266728
-
Dissociation constants of some carboxylic acids in mixed aqueous solvents
-
Yasuda M. Dissociation constants of some carboxylic acids in mixed aqueous solvents. Bull Chem Soc Jpn 1959; 32: 429-432.
-
(1959)
Bull Chem Soc Jpn
, vol.32
, pp. 429-432
-
-
Yasuda, M.1
-
21
-
-
0025091286
-
Relationships beetween octanol-water partition data, Chromatographic indices and their dependence on pH in a set of β-adrenoceptor blocking agents
-
Barbato F, Caliendo G, La Rotonda MI, Morrica P, Silipo C, Vittoria A. Relationships beetween octanol-water partition data, Chromatographic indices and their dependence on pH in a set of β-adrenoceptor blocking agents. II Farmaco 1990; 45: 647-663.
-
(1990)
II Farmaco
, vol.45
, pp. 647-663
-
-
Barbato, F.1
Caliendo, G.2
La Rotonda, M.I.3
Morrica, P.4
Silipo, C.5
Vittoria, A.6
-
22
-
-
0026500193
-
Partition and distribution coefficients of aryloxypropanolamine β-adrenoceptor antagonists
-
Recanatini M. Partition and distribution coefficients of aryloxypropanolamine β-adrenoceptor antagonists. J Pharm Pharmacol 1992; 44: 68-70.
-
(1992)
J Pharm Pharmacol
, vol.44
, pp. 68-70
-
-
Recanatini, M.1
-
23
-
-
0017814736
-
Adrenoceptor blockade of the circulatory responses to intravenous isoproterenol
-
Richard DA, Prichard BNC, Dobbs RJ. Adrenoceptor blockade of the circulatory responses to intravenous isoproterenol. Clin Pharmacol Ther 1978; 24: 264-273.
-
(1978)
Clin Pharmacol Ther
, vol.24
, pp. 264-273
-
-
Richard, D.A.1
Prichard, B.N.C.2
Dobbs, R.J.3
-
24
-
-
0020456025
-
How intrinsic sympathomimetic activity modulates the haemodynamic responses to β-adrenoceptor antagonists. A clue to the nature of their antihypertensive mechanism
-
Man In't Veld AJ, Schalekamp MADH. How intrinsic sympathomimetic activity modulates the haemodynamic responses to β-adrenoceptor antagonists. A clue to the nature of their antihypertensive mechanism. Br J Clin Pharmacol 1982; 13 (Suppl 2): 245S-257S.
-
(1982)
Br J Clin Pharmacol
, vol.13
, Issue.2 SUPPL.
-
-
Man In't Veld, A.J.1
Schalekamp, M.A.D.H.2
-
25
-
-
0026349833
-
Blood pressure reduction in relation to β-blockade in healthy volunteers
-
Van Rooy P, Van Nueten L, De Cree J. Blood pressure reduction in relation to β-blockade in healthy volunteers. Drug Investig 1991; 3 (Suppl. 1): 174-175.
-
(1991)
Drug Investig
, vol.3
, Issue.1 SUPPL.
, pp. 174-175
-
-
Van Rooy, P.1
Van Nueten, L.2
De Cree, J.3
-
26
-
-
0018386403
-
The effect of ageing on the hepatic clearance of propranolol
-
Castleden CM, George CF. The effect of ageing on the hepatic clearance of propranolol. Br J Clin Pharmacol 1979; 7: 49-54.
-
(1979)
Br J Clin Pharmacol
, vol.7
, pp. 49-54
-
-
Castleden, C.M.1
George, C.F.2
-
27
-
-
0023010417
-
A comparison of the pharmacokinetics of propranolol in obese and normal volunteers
-
Bowman SL, Hudson SA, Simpson G, et al. A comparison of the pharmacokinetics of propranolol in obese and normal volunteers. Br J Clin Pharmacol 1986; 21: 529-537.
-
(1986)
Br J Clin Pharmacol
, vol.21
, pp. 529-537
-
-
Bowman, S.L.1
Hudson, S.A.2
Simpson, G.3
-
28
-
-
0021195730
-
Comparison of the clinical pharmacokinetics and concentration-effect relationships for medroxalol and labetalol
-
Elliott HL, Meredith PA, Summer DJ, Reid JL. Comparison of the clinical pharmacokinetics and concentration-effect relationships for medroxalol and labetalol. Br J Clin Pharmacol 1984; 17: 573-578.
-
(1984)
Br J Clin Pharmacol
, vol.17
, pp. 573-578
-
-
Elliott, H.L.1
Meredith, P.A.2
Summer, D.J.3
Reid, J.L.4
-
29
-
-
8544265046
-
Pharmacodynamics and disposition of labetalol in elderly hypertensive patient
-
Abernethy DR, Schwartz JB, Plachetka J, et al. Pharmacodynamics and disposition of labetalol in elderly hypertensive patient. J Clin Pharmacol 1985; 25: 468.
-
(1985)
J Clin Pharmacol
, vol.25
, pp. 468
-
-
Abernethy, D.R.1
Schwartz, J.B.2
Plachetka, J.3
-
31
-
-
0017188804
-
Influence of muscular development, obesity and age on the fat-free mass of adults
-
Womersley J, Durning JVGA, Boddy K, Mahaffy M. Influence of muscular development, obesity and age on the fat-free mass of adults. J Appl Physiol 1976; 47: 223-229
-
(1976)
J Appl Physiol
, vol.47
, pp. 223-229
-
-
Womersley, J.1
Durning, J.V.G.A.2
Boddy, K.3
Mahaffy, M.4
-
32
-
-
8544252120
-
Lipophilicity and hydrogen bonding capacity: Their role in drug binding and disposition
-
Éditions Fort et Clair Paris
-
Testa B, El Tayar N, Altomare C, Carrupt PA, Tsai RS. Lipophilicity and hydrogen bonding capacity: their role in drug binding and disposition. In Proceedings of the International Symposium on blood binding and drug transfer. Éditions Fort et Clair Paris, 1993: 109-120.
-
(1993)
Proceedings of the International Symposium on Blood Binding and Drug Transfer
, pp. 109-120
-
-
Testa, B.1
El Tayar, N.2
Altomare, C.3
Carrupt, P.A.4
Tsai, R.S.5
-
33
-
-
0025731738
-
Partitioning of solutes in different solvent systems: The contribution of hydrogen-bonding capacity and polarity
-
El Tayar N, Tsai RS, Testa B, Carrupt PA, LEO A. Partitioning of solutes in different solvent systems: the contribution of hydrogen-bonding capacity and polarity. J Pharm Sci 1991; 80: 590-598.
-
(1991)
J Pharm Sci
, vol.80
, pp. 590-598
-
-
El Tayar, N.1
Tsai, R.S.2
Testa, B.3
Carrupt, P.A.4
Leo, A.5
-
34
-
-
0001712289
-
Polar interactions encoded in partition coefficients: An indirect estimation of hydrogen-bond parameters of polyfunctional solutes
-
El Tayar N, Testa B, Carrupt PA. Polar interactions encoded in partition coefficients: An indirect estimation of hydrogen-bond parameters of polyfunctional solutes. J Physic Chem 1992; 96: 1455-1459.
-
(1992)
J Physic Chem
, vol.96
, pp. 1455-1459
-
-
El Tayar, N.1
Testa, B.2
Carrupt, P.A.3
-
35
-
-
0026064678
-
Percutaneous penetration of drugs: A quantitative structure-permeation relationship study
-
El Tayar N, Tsai RS, Testa B, Carrupt PA, Hansch C, Leo A. Percutaneous penetration of drugs: A quantitative structure-permeation relationship study. J Pharm Sci 1991; 80: 744-749.
-
(1991)
J Pharm Sci
, vol.80
, pp. 744-749
-
-
El Tayar, N.1
Tsai, R.S.2
Testa, B.3
Carrupt, P.A.4
Hansch, C.5
Leo, A.6
-
36
-
-
0028289107
-
Factors affecting the storage of drugs and other xenobiotics in adipose tissue
-
eds Testa B, Meyer UA, Academic Press, London
-
BickeL MH. Factors affecting the storage of drugs and other xenobiotics in adipose tissue. In Advances in Drug Research, Vol. 25, eds Testa B, Meyer UA, Academic Press, London, 1994: 55-86.
-
(1994)
Advances in Drug Research
, vol.25
, pp. 55-86
-
-
Bickel, M.H.1
|