Influence of treadmill running on femoral bone in young orchidectomized rats

Journal of Applied Physiology

Volumn 83, Issue 1, 1997, Pages 129-133

  Horcajada, M N ^a   Coxam, V ^a   Davicco, M J ^a   Gaumet, N ^a   Pastoureau, P ^b   Leterrier, C ^a   Culioli, J ^a   Barlet, J P ^a  

^a CEMAGREF   (France)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Deoxypyridinoline; Exercise; Osteocalcin; Osteoporosis

Indexed keywords

DEOXYPYRIDINOLINE; OSTEOCALCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; CASTRATION; CONTROLLED STUDY; EXERCISE; FEMUR; IMAGE ANALYSIS; MALE; NONHUMAN; ORCHIECTOMY; OSTEOBLAST; OSTEOLYSIS; PRIORITY JOURNAL; RAT; TREADMILL;

EID: 0030875004     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.1.129     Document Type: Article

References (42)

1. Banes, A. J., M. Tsuzaki, J. Yamamoto, T. Fischer, B. Brigman, T. Brown, and L. Miller. Mechanoreception at the cellular level: the detection, interpretation and diversity of responses to mechanical signals. Biochem. Cell Biol. 73: 349-365, 1995.
2. Bourrin, S., C. Genty, S. Palle, C. Gharib, and C. Alexandre. Adverse effects of strenuous exercise: a densitometric and histomorphometric study in the rat. J. Appl. Physiol. 76: 1999-2005, 1994
3. Bourrin, S., F. Ghaemmaghami, L. Vico, D. Chappard, C. Gharib, and C. Alexandre. Effect of a five-week swimming program: a histomorphometric study. Calcif. Tissue Int. 51: 137-142, 1992.
4. Burr, D. B., and R. B. Martin. Errors in bone remodeling: toward a unified theory of metabolic bone disease. Am. J. Anat. 186: 186-226, 1989.
5. Colvard, C. S., E. F. Eriksen, P. E. Keeting, E. M. Wilson, D. B. Lubahn, F. S. French, L. B. Riggs, and T. C. Spelsberg. Identification of androgen receptors in normal human osteoblast-like cells. Proc. Natl. Acad. Sci. USA 86: 854-857, 1989.
6. Cook, J. G. H. Factors influencing the assay of creatinine. Ann. Clin. Biochem. 12: 219-232, 1975.
7. De Vernejoul, M.-C., and P. Marie. Cellules osseuses et remodelage osseux. Med. Sci. 9: 1192-1203, 1993.
8. Forwood, M. R., and A. W. Parker. Repetitive loading, in vivo, of the tibiae and femura of rats; effects of repeated bouts of treadmill-running. Bone Miner. 13: 35-46, 1991.
9. Frost, H. M. Bone "mass" and the "mechanostat": a proposal. Anat. Rec. 219: 1-9, 1987.
10. Gaumet, N., M. J. Seibel, P. Braillon, J. Giry, P. Lebecque, M.-J. Davicco, V. Coxam, J. Rouffet, P. D. Delmas, and J.-P. Barlet. Influence of ovariectomy on bone metabolism in very old rats. Calcif. Tissue Int. 58: 256-262, 1996.
11. Golding, V. S. R. The mechanical factors which influence bone growth. Eur. J. Clin. Nutr. 48, Suppl. 1: S178-S185, 1994.
12. Griffin, M. G., R. Kimble, W. Hopfer, and R. Pacifici. Dual energy X-ray absorptiometry of the rat: accuracy, precision and measurement of bone loss. J. Bone Miner. Res. 8: 795-800, 1993.
13. Hollozy, J. O., and F. W. Booth. Biochemical adaptation to endurance exercise in muscle. Annu. Rev. Physiol. 38: 273-291, 1976.
14. Jones, D., G. Leivseth, and J. Tenbosch. Mechano-reception in osteoblast-like cells. Biochem. Cell Biol. 73: 525-534, 1995.
15. Kannis, P., H. Sievanen, and I. Vuori. Physical loading, exercise and bone. Bone 18, Suppl. 1: 1S-3S, 1996.
16. Kasperk, C. H., K. Faehling, I. Börcskörk, and R. Ziegler. Effects of androgens on subpopulations of the human osteosarcoma cell line SaOS2. Calcif. Tissue Int. 58: 376-382, 1996.
17. Kasperk, C. H., J. E. Wergedal, J. R. Farley, T. A. Linkhart, R. T. Turner, and D. J. Baylink. Androgens directly stimulate proliferation of bone cells in vitro. Endocrinology 124: 1576-1578, 1989.
18. Lawler, J. M., S. K. Powers, J. Hammeren, and A. D. Martin. Oxygen cost of treadmill-running in 24-month-old Fischer-344 rats. Med. Sci. Sports Exerc. 25: 1259-1264, 1993.
19. Leblanc, A. D., H. J. Evans, P. C. Johnson, and S. Jhingran. Changes in total body calcium balance with exercise in the rat. J. Appl. Physiol. 55: 201-204, 1983.
20. Newhall, K. M., K. J. Rodnick, M. C. Van Der Meulen, D. R. Carter, and R. Marcus. Effects of voluntary exercise on bone mineral content in rats. J. Bone Miner: Res. 6: 289-296, 1991.
21. Ongphiphadhanakul, B., S. Alex, L. E. Braverman, and D. T. Baran. Excessive L-thyroxine therapy decreases femoral bone mineral densities in the male rat: effect of hypogonadism and calcitonin. J. Bone Miner. Metab. 1: 1227-1231, 1992.
22. Pastoureau, P., A. Chomel, and J. Bonnet. Specific evaluation of localized bone mass and bone loss in the rat using dual energy X-ray absorptiometry subregional analysis. Osteoporos. Int. 5: 143-149, 1995.
23. Robins, S. P. Biochemical markers for assessing skeletal growth. Eur. J. Clin. Nutr. 48, Suppl. 1: S199-S209, 1994.
24. Rose, N., P. Constantin, and C. Leterrier. Sex differences in bone growth of broiler chickens. Growth Dev. Aging 60: 49-59, 1996.
25. Rosen, H. N., S. Tollin, R. Balena, V. L. Middlebrooks, W. G. Beamer, L. R. Donohue, C. Rosen, A. Turner, M. Holick, and S. L. Greenspan. Differentiating between orchidectomized rats and controls using measurements of trabecular bone density: a comparison between DXA, histomorphometry, and peripheral quantitative tomography. Calcif. Tissue Int. 57: 35-39, 1995.
26. Saville, P. D. Changes in skeletal mass and fragility with castration in the rat: a model of osteoporosis. J. Am. Geriatr. Soc. 17: 155-166, 1969.
27. Saville, P. D., and M. P. White. Muscle and bone hypertrophy. Positive effect of running exercise in the rat. Clin. Orthop. 65: 81-88, 1969.
28. Schoutens, A., M. Verhas, M. L'Hermite-Baleriaux, M. L'Hermite, A. Verschaeren, N. Douron, M. Mone, A. Heilporn, and A. Tricot. Growth and bone haemodynamic responses to castration in male rats. Reversibility by testosterone. Acta Endocrinol. 107: 428-432, 1984.
29. Seibel, M. J., S. P. Robins, and J. P. Bilezikian. Urinary pyridinium crosslinks of collagen. Specific markers of bone resorption in metabolic bone disease. Trends Endocrinol. Metab. 3: 263-270, 1992.
30. Seyedin, S. M., V. T. Kung, Y. N. Daniloff, R. P. Helsey, B. Gomez, L. A. Neilsen, H. N. Rosen, and R. F. Zuk. Immunoassay for urinary pyridinoline: the new marker for bone resorption. J. Bone Miner. Res. 5: 635-641, 1993.
31. Shimegi, S., S. Katsuta, H. Amagi, and A. Ohno. Exercise-induced bone hypertrophy in growing rats. Jpn. J. Fitness Sports Med. 39: 181-188, 1990.
32. Swissa-Sivan, A., A. Simkin, I. Leichter, A. Nyska, M. Nyska, M. Statter, M. Bivas, J. Menczel, and S. Samueloff. Effects of swimming on bone growth and development in young rats. Bone Miner. 7: 91-105, 1989.
33. Turner, C. H., and C. B. Burr. Basic mechanical measurements of bone: a tutorial. Bone 14: 595-608, 1993.
34. Tuukanen, J., Z. Peng, and H. K. Väänänen. Effect of running exercise on the bone loss induced by orchidectomy in the rat. Calcif. Tissue Int. 55: 33-37, 1995.
35. Umemura, Y., T. Ishito, K. Aoki, and A. Gunji. Effects of voluntary exercise on bone growth and calcium metabolism in spontaneously hypertensive rats. Int. J. Sports Med. 13: 476-480, 1992.
36. Umemura, Y., T. Ishito, H. Tsujimoto, H. Miura, N. Mokushi, and H. Suzuki. Effects of jump training on bone hypertrophy in young and old rats. Int. J. Sports Med. 16: 364-367, 1995.
37. Vanderschueren, D., E. Van Heck, P. Schot, E. Rush, T. Einhorn, P. Geusens, and R. Bouillon. The aged male rat as a model for human osteoporosis: evaluation by non destructive measurements and biomechanical testing. Calcif. Tissue Int. 53: 342-347, 1993.
38. Wakley, G. K., H. D. Schutte, K. S. Hannon, and R. T. Turner. Androgen treatment prevents loss of cancellous bone in the orchidectomized rat. J. Bone Miner. Res. 6: 325-330, 1991.
39. Wheeler, D. L., J. E. Graves, G. J. Miller, R. E. Van Der Griend, T. J. Wronski, S. K. Powers, and H. M. Park. Effects of running on the torsional strength, morphometry, and bone mass of the rat skeleton. Med. Sci. Sports Exerc. 27: 520-529, 1995.
40. Wink, C. S., and W. J. L. Felts. Effects of castration on the bone structure of male rats: a model of osteoporosis. Calcif. Tissue Int. 32: 77-82, 1980.
41. Woo, S. L. Y., S. C. Kuei, D. Amiel, M. A. Gomez, W. C. Hayes, F. C. White, and W. H. Akeson. The effect of prolonged physical training on the properties of long bone: a study of Wolff's law. J. Bone Joint Surg. 63A: 780-787, 1981.
42. Yeh, J. K., C. G. Liu, and J. F. Aloia. Effect of exercise and immobilization on bone formation and resorption in young rats. Am J Physiol. 264 (Endocrinol. Metab. 27): E182-E189, 1993.