Supersensitivity in rat micro-arteries after short-term denervation

Acta Physiologica Scandinavica

Volumn 161, Issue 2, 1997, Pages 125-133

  Bentzer, P ^a   Nielsen, N ^a   Arner, M ^b   Danielsen, N ^a,b   Ekblad, E ^a   Lundborg, G ^b   Arner, A ^a,c  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c Dept of Physiology and Neuroscience ^*  (Sweden)

Author keywords

Calcitonin gene related peptide; Calcium; Denervation; Micro arteries; Neuropeptide Y; Phenylephrine; Potassium; Supersensitivity; Vascular smooth muscle; Vasospasm

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; NEUROPEPTIDE Y; PHENYLEPHRINE; POTASSIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTERY; ARTICLE; CONTROLLED STUDY; DENERVATION; FEMALE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MICROVASCULATURE; MYOGRAPHY; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; RAT; SAPHENOUS NERVE; SCIATIC NERVE; SUPERSENSITIVITY; VASCULAR SMOOTH MUSCLE;

EID: 0030873940     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1997.00177.x     Document Type: Article

References (31)

1. Bevan, J.A. & Brayden, J.E. 1987. Nonadrenergic neuronal vasodilator mechanisms. Circ Res 60, 309-326.
2. Bevan, R.D. & Tsuru, H. 1981. Functional and structural changes in the rabbit ear after after sympathetic denervation. Circ Res 49, 478-485.
3. Bevan, R.D., Clemenrson, A., Joyce, E. & Bevan, J.A. 1993. Sympathetic denervation of resistance arteries increases contraction and decreases relaxation to flow. Am J Physiol 264, H490-H494.
4. Boels, P.J., Arner, A., Malmqvist, U. & Uvelius, B. 1994. Structure and mechanics of growing arterial microvessels from hypertrophied urinary bladder in the rat. Pflügers Arch 426, 506-515.
5. Bornmyr, S., Arner, M. & Svensson, H. 1994. Laser doppler imaging of finger skin blood flow in patients after microvascular repair of the ulnar artery at the wrist. J Hand Surg Br 19, 295-300.
6. Cannon, W.B. 1939. A law of denervation. Am J Med Sci 198, 737-750.
7. Carrier, O. & Hester, R.K. 1976. The relationship between calcium and increased sensitivity of rabbit aortae four hours after reserpine. Br J Pharmacol 56, 449-455.
8. Chen, L.-E., Seaber, A.V., Bossen, E. & Urbaniak, J.R. 1991 The effect of acute denervation on the microcirculation of skeletal muscle: Rat cremaster model. J Orthop Res 9, 266-274.
9. Cohen, R.A., Tesfamariam, B., Weisbrod, R.M. & Zitnay, K.M. 1990. Adrenergic denervation in rabbits with diabetes mellitus. Am J Physiol 259, H55-61.
10. Colucci, W.S., Gimbrone, M.A. & Alexander, R.W. 1981. Regulation of the postsynaptic α-adrenergic receptor in rat mesenteric artery. Effects of chemical sympathectomy and epinephrine treatment. On Res 48, 104-111.
11. Dimitriadou, V., Aubineau, P., Taxi, J. & Seylas, J. 1988. Ultrastructural changes in the cerebral artery wall induced by long-term sympathetic denervation. Blood Vessels 25, 122-143.
12. Ekblad, E., Winther, C., Ekman, R., Håkanson, R. & Sundler, F. 1987. Projections of peptide containing neurons in rat small intestine. Neurosci 20, 169-188.
13. Fleming, W.W., McPhillips, J.J. & Westfall, D.P. 1973. Postjunctional supersensitivity and subsensitivity of excitable tissues to drugs. Rev Physiol Biochem Exp Pharmacol 68, 55-119.
14. Fleming, B.P. 1988. Innervation of the microcirculation. J Reconstr Microsurg 4, 237-240.
15. Gemne, G. 1994. Pathophysiology of white fingers in workers using hand-held vibrating tools. Nagoya J of Med Sci [Suppl.] 57, 87-97.
16. Gerthoffer, W.T., Fedan, J.S., Westfall, D.P., Goto, K. & Fleming, W.W. 1979. Involvement of the sodium-potassium pump in the mechanism of postjunctional supersensitivity of the vas deferens of guinea pig. J Pharmacol Exp Ther 210, 27-36.
17. Grant, B.T. 1966. The effects of denervation on skeletal muscle blood vessels (rat cremaster). J Anat 100, 305-316.
18. Greene, E.C. 1963. Anatomy of the Rat, pp. 1-370. Hafner Publishing Company. New York.
19. +-ATPase. Mol Pharmacol 43, 833-837.
20. Lundborg, G., Daklin, L.B., Hansson, H.A., Kanje, M. & Necking, L.E. 1990. Vibration exposure and peripheral nerve fiber damage. J Hand Surg 15 A, 346-351.
21. Mangiarua, M.I. & Bevan, R.D. 1986. Altered endothelium-mediated relaxation after denervation of growing rabbit ear artery. Eur J Pharmacol 122, 149-152.
22. Midrio, M., Corsi, A. & Granata, A.L. 1968. Early effects of nerve section on the blood flow of skeletal muscle. Am J Physiol 214, 287-293.
23. Mulvany, M.J. & Aalkjaer, C. 1990. Structure and function of small arteries. Physiol Rev 70, 921-961.
24. Mulvany, M.J. & Halpern, W. 1976. Mechanical properties of vascular smooth muscle cells in situ. Nature 260, 617-619.
25. Osinsky, M., Bass, P. 1995. Myenteric denervation of rat jejunum alters calcium responsiveness of intestinal smooth muscle. Gastroenterology 108, 1629-1636.
26. Ramos, K., Gerthoffer, W., Westfall, D. 1986. Denervation-induced supersensitivity to calcium of chemically skinned smooth muscle of the guinea-pig vas deferens. J Pharmacol Exp Ther 236, 80-85.
27. Saito, M., Gotoh, M., Kato, K., Kondo, A. 1989. Denervation supersensitivity of the rabbit urinary bladder to calcium ion. J Urol 142, 418-21.
28. Shibata, S., Kuchii, M. & Kurahashi, K. 1972. The supersensitivity of isolated rabbit atria and aortic strips produced by 6-hydroxydopamine. Eur J Pharmacol 18, 271-80.
29. Sundler, F., Brodin, E., Ekblad, E., Håkanson, R. & Uddman, R. 1985. Sensory nerve fibers: Distribution of substance P, neurokinin A and calcitonin gene related peptide. In: R. Håkansson & F. Sundler (eds). Tachykinin Antagonists Proceedings of the 8th Fernström Symposium, 1985, pp. 3-14. Elsevier, Amsterdam.
30. Todd, M.E. & Bevan, R.D. 1991. Effects of postnatal growth and denervation on characteristics of the saphenous artery in SHR and WKY rats between 3 and 6 weeks of age: an in vitro study. Can J Physiol Pharmacol 69, 731-738.
31. + after denervation and decentralization in rabbit ear artery. Eur J Pharmacol 84, 9-16.