Aminopeptidase N-mediated signal transduction and inhibition of proliferation of human myeloid cells

Advances in Experimental Medicine and Biology

Volumn 421, Issue , 1997, Pages 85-91

  Lohn M ^a   Mueller, C ^a   Thiele, K ^a   Kahne T ^b   Riemann, D ^a   Langner, J ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; MICROSOMAL AMINOPEPTIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CALCIUM TRANSPORT; CELL DENSITY; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; IMMUNOMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATOR GENE; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0030873818     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-9613-1_12     Document Type: Article

References (17)

1. Brownlees, J., Williams, C.H. (1993) Peptidases, peptides. and the mammalian blood-brain barrier. J. Neurochem. 60, 793-803
2. Kohno, H., Kanno, T. (1985) Properties and activities of aminopeptidases in normal and mitogen stimulated human lymphocytes. J.Biochem. 226, 59-65
3. Kohno, H., Kanno, T. (1985) Intracellular localization and properties of aminopeptidases in human peripheral blood lymphocytes. Int. J. Biochem. 17, 1143-1148
4. Taylor, A. (1993) Aminopeptidases: towards a mechanism of action. TIBS 18, 167-172
5. Sanderink, G.-J., Artur,Y., Siest, G. (1988) Human aminopeptidase: A review of the literature. J. Clin Chem. Biochem. 26, 795-807
6. Riemann, D., Göhring, B., Langner, J. (1994) Expression of aminopeptidase N/CD13 in tumor-infiltrating lymphocytes from human renal cell carcinoma. Immunol. Lett. 42, 19-23
7. Razak, K., Newland, A.C. (1992) The significance of aminopeptidase and haematopoetic cell differentation. Blood Rev. 6, 243-250
8. Look, A.T. (1989) Human myeloid plasma membrane glycoprotein CD13 (gp 150) is identical to aminopeptidase N. J.Clin.Invest. 83, 1299-1307
9. Mattern, T., Ansorge, S., Flad, H-D., Ulmer, A. (1993) Anti-CD26 monoclonal antibodies can reversibly arrest human T lymphocytes in the late G, phase of the cell cycle. Immunbiol. 188, 36-50
10. Reinhold, D., Bank, U., Bühling, F., Kähne, T., Kunz, D., Faust, J., Neubert, K., Ansorge, S. (1994) Inhibitors of Dipeptidyl peptidase IV (DPIV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells. Immunbiol. 192, 121-136
11. Murata, M., Kubota, Y., Tanaka, T., Iida-Tanaka, K., Takahara, J., Irino, S. (1994) Effect of ubenimex on the proliferation and differentation of U937 human histiocytic lymphoma cells. Leukemia 8, 2188-2193
12. Shibuya, K., Chiba, S., Hino, M., Kitamura, T., Miyagawa, K., Takaku, F., Miyazano, K. (1991) Enhancing effect of ubenimex (Bestatin) on proliferation and differentiation of hematopoietic progenitor cells, and the suppressive effect on proliferation of leukemia cell lines via peptidase regulation. Biomed. Pharmacother. 45, 71-80
13. Hass, R., Meinhardt, G., Hadam, M., Bartels, H. (1994) Characterization of human TUR leukemia cells: continued cell cycle progression in the presence of phorbol esters is associated with the resistance to apoptosis. Eur. J. Cell. Biol. 65, 408-416
14. Hütter, H.J. (1984) Characterization of human alanine aminopeptidases. Symposia Biologica Hungaria 25
15. MacIntyre, E.A. ,Roberts, P.J., Jones, M., van der School, C.E., Favalaro,E.J., Tidman, N., Linch, D.C. (1989) Activation of human monocytes occurs on cross-linking monocytic antigens to an Fc receptor. J. Immunol. 142, 2377-2383
16. MacIntyre, E.A. ,Roberts, P.J.,Abdul-Gaffar, R., O'Flynn, K., Pilkington, G.R., Farace, F., Morgan, J., Linch, D.C. (1988) Mechanism of human monocytes activation via the 40-kDa Fc-receptor for IgG. J. Immunol. 141, 4333-4343
17. Hollenberg, M. D. (1996) Protease-mediated signalling: new paradigms for cell regulation and drug develoment. TIPS 17, 3-6