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Volumn 57, Issue 4, 1997, Pages 785-791

Activating the posttraumatic cholinergic system for the treatment of cognitive impairment following traumatic brain injury

Author keywords

Lu 25 109 T; M1 agonist; M2 antagonist; Morris water maze; Muscarinic; Rats; Spatial memory; Treatment

Indexed keywords

ALVAMELINE; MUSCARINIC M1 RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 0030873742     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(96)00453-4     Document Type: Article
Times cited : (43)

References (41)
  • 1
    • 0023899578 scopus 로고
    • Mechanisms of cholinesterase inhibition in senile dementia of the Alzheimer's type: Clinical, pharmacological, and therapeutic aspects
    • Becker, R. E.; Giacobini, E.: Mechanisms of cholinesterase inhibition in senile dementia of the Alzheimer's type: Clinical, pharmacological, and therapeutic aspects.Drug Dev. Res. 12:163-195; 1988.
    • (1988) Drug Dev. Res. , vol.12 , pp. 163-195
    • Becker, R.E.1    Giacobini, E.2
  • 2
    • 0019457723 scopus 로고
    • In vivo modulation of the number of muscarinic receptors in rat brain by cholinergic ligands
    • Ben-Barak, J.; Gazit, H.; Silman, I.; Dudai, Y.: In vivo modulation of the number of muscarinic receptors in rat brain by cholinergic ligands. Eur. J. Pharmacol. 74:73-81; 1981.
    • (1981) Eur. J. Pharmacol. , vol.74 , pp. 73-81
    • Ben-Barak, J.1    Gazit, H.2    Silman, I.3    Dudai, Y.4
  • 4
    • 0024503448 scopus 로고
    • Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes
    • Buyukuysal, R. L.; Wurtman, R. J.: Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes. Brain Res. 482:371-375; 1989.
    • (1989) Brain Res. , vol.482 , pp. 371-375
    • Buyukuysal, R.L.1    Wurtman, R.J.2
  • 5
    • 0026494811 scopus 로고
    • Cognitive impairment following closed head injury
    • Capruso, D. X.; Levin, H. S.: Cognitive impairment following closed head injury. Neurol. Clin. 10:879-893; 1992.
    • (1992) Neurol. Clin. , vol.10 , pp. 879-893
    • Capruso, D.X.1    Levin, H.S.2
  • 7
    • 0024217629 scopus 로고
    • Effects of traumatic brain injury on cerebral blood flow and metabolism: Autoradiographic studies
    • DeWitt, D. S.; Hayes, R. L.; Lyeth, B. G.; Yuan, X. Q.; Prough, D. S.: Effects of traumatic brain injury on cerebral blood flow and metabolism: Autoradiographic studies.Anesth. Rev. 15:31-32; 1988.
    • (1988) Anesth. Rev. , vol.15 , pp. 31-32
    • DeWitt, D.S.1    Hayes, R.L.2    Lyeth, B.G.3    Yuan, X.Q.4    Prough, D.S.5
  • 8
    • 0028784132 scopus 로고
    • Basal and scopolamine-evoked release of hippocampal acetylcholine following traumatic brain injury in rats
    • Dixon, C. E.; Bao, J.; Johnson, K. M.; Yang, K.; Whitson, J.; Clifton, G. L.; Hayes, R. L.: Basal and scopolamine-evoked release of hippocampal acetylcholine following traumatic brain injury in rats. Neurosci. Lett. 198:111-114; 1995.
    • (1995) Neurosci. Lett. , vol.198 , pp. 111-114
    • Dixon, C.E.1    Bao, J.2    Johnson, K.M.3    Yang, K.4    Whitson, J.5    Clifton, G.L.6    Hayes, R.L.7
  • 9
    • 0001420077 scopus 로고
    • Nerve growth factor (NGF) reduces decreases in spatial memory performance and choline acetyltransferase (ChAT) immunoreactivity in the medial septal area following traumatic brain injury
    • Dixon, C. E.; Flinn, P.; Bao, J.; Yang, K.; Whitson, G. L.; Clifton, G. L.; Hayes, R. L.: Nerve growth factor (NGF) reduces decreases in spatial memory performance and choline acetyltransferase (ChAT) immunoreactivity in the medial septal area following traumatic brain injury. Soc. Neurosci. Abstr. 21:762; 1995.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 762
    • Dixon, C.E.1    Flinn, P.2    Bao, J.3    Yang, K.4    Whitson, G.L.5    Clifton, G.L.6    Hayes, R.L.7
  • 10
    • 0028788393 scopus 로고
    • Time course of increased vulnerability of cholinergic neurotransmission following traumatic brain injury in the rat
    • Dixon, C. E.; Liu, S.; Jenkins, L. W.; Bhattachargee, M.; Whitson, J. S.; Yang, K.; Hayes, R. L.: Time course of increased vulnerability of cholinergic neurotransmission following traumatic brain injury in the rat. Behav. Brain Res. 70:125-131; 1995.
    • (1995) Behav. Brain Res. , vol.70 , pp. 125-131
    • Dixon, C.E.1    Liu, S.2    Jenkins, L.W.3    Bhattachargee, M.4    Whitson, J.S.5    Yang, K.6    Hayes, R.L.7
  • 12
    • 0028927110 scopus 로고
    • 2 antagonists as potential drugs for cognitive disorders
    • 2 antagonists as potential drugs for cognitive disorders. Drugs Future 20:157-164; 1995.
    • (1995) Drugs Future , vol.20 , pp. 157-164
    • Doods, H.N.1
  • 13
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden, A. I.; Demediuk, P.; Panter, S. S.; Vink, R.: The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244:798-800; 1989.
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 14
    • 0027723295 scopus 로고
    • Selective cognitive impairment following traumatic brain injury in rats
    • Hamm, R. J.; Lyeth, B. G.; Jenkins, L. W.; O'Dell, D. M.; Pike, B. R.: Selective cognitive impairment following traumatic brain injury in rats. Behav. Brain Res. 59:169-173; 1993.
    • (1993) Behav. Brain Res. , vol.59 , pp. 169-173
    • Hamm, R.J.1    Lyeth, B.G.2    Jenkins, L.W.3    O'Dell, D.M.4    Pike, B.R.5
  • 15
    • 0027727646 scopus 로고
    • Cognitive impairment following traumatic brain injury: The effect of preand post-injury administration of scopolamine and MK-801
    • Hamm, R. J.; O'Dell, D. M.; Pike, B. R.; Lyeth, B. G.: Cognitive impairment following traumatic brain injury: The effect of preand post-injury administration of scopolamine and MK-801.Cognit. Brain Res. 1:223-226; 1993.
    • (1993) Cognit. Brain Res. , vol.1 , pp. 223-226
    • Hamm, R.J.1    O'Dell, D.M.2    Pike, B.R.3    Lyeth, B.G.4
  • 16
    • 0028087914 scopus 로고
    • Traumatic brain injury enhances the amnesic effect of a NMDA antagonist in rats
    • Hamm, R. J.; Pike, B. R.; O'Dell, D. M.; Lyeth, B. G.: Traumatic brain injury enhances the amnesic effect of a NMDA antagonist in rats. J. Neurosurg. 81:267-271; 1994.
    • (1994) J. Neurosurg. , vol.81 , pp. 267-271
    • Hamm, R.J.1    Pike, B.R.2    O'Dell, D.M.3    Lyeth, B.G.4
  • 17
    • 0028229190 scopus 로고
    • The rotarod test: An evaluation of its effectiveness in assessing motor deficits following traumatic brain injury
    • Hamm, R. J.; Pike, B. R.; O'Dell, D. M.; Lyeth, B. G.; Jenkins, L. W.: The rotarod test: An evaluation of its effectiveness in assessing motor deficits following traumatic brain injury. J. Neurotrauma 11:187-196; 1994.
    • (1994) J. Neurotrauma , vol.11 , pp. 187-196
    • Hamm, R.J.1    Pike, B.R.2    O'Dell, D.M.3    Lyeth, B.G.4    Jenkins, L.W.5
  • 18
    • 0026476043 scopus 로고
    • The effect of age on motor and cognitive deficits after traumatic brain injury in rats
    • Hamm, R. J.; White-Gbadebo, D.; Lyeth, B. G.; Jenkins, L. W.; Hayes, R. L.: The effect of age on motor and cognitive deficits after traumatic brain injury in rats. Neurosurgery 31:1072-1078; 1992.
    • (1992) Neurosurgery , vol.31 , pp. 1072-1078
    • Hamm, R.J.1    White-Gbadebo, D.2    Lyeth, B.G.3    Jenkins, L.W.4    Hayes, R.L.5
  • 19
    • 0000040887 scopus 로고
    • Pretreatment with phencyclidine, an N-methyl-D-aspartate receptor antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury
    • Hayes, R.; Jenkins, L.; Lyeth, B.; Balster, R.; Robinson, S.; Clifton, G.; Stubbins, J.; Young, H.: Pretreatment with phencyclidine, an N-methyl-D-aspartate receptor antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury. J. Neurotrauma 5:287-302; 1988.
    • (1988) J. Neurotrauma , vol.5 , pp. 287-302
    • Hayes, R.1    Jenkins, L.2    Lyeth, B.3    Balster, R.4    Robinson, S.5    Clifton, G.6    Stubbins, J.7
  • 20
    • 0028108599 scopus 로고
    • Fluid percussion injury causes loss of forebrain choline acetyltransferase and nerve growth factor receptor immunoreactive cells in the rat
    • Leonard, J. R.; Maris, D. O.; Grady, M. S.: Fluid percussion injury causes loss of forebrain choline acetyltransferase and nerve growth factor receptor immunoreactive cells in the rat. J. Neurotrauma 11:379-392; 1994.
    • (1994) J. Neurotrauma , vol.11 , pp. 379-392
    • Leonard, J.R.1    Maris, D.O.2    Grady, M.S.3
  • 21
    • 0011121182 scopus 로고
    • The effects of varying doses of CDP-choline on recovery of spatial memory function following controlled cortical impact injury in rats
    • Liu, S. J.; Dixon, C. E.; Hayes, R. L.: The effects of varying doses of CDP-choline on recovery of spatial memory function following controlled cortical impact injury in rats. Soc. Neurosci. Abstr. 19: 1881; 1993.
    • (1993) Soc. Neurosci. Abstr. , vol.19 , pp. 1881
    • Liu, S.J.1    Dixon, C.E.2    Hayes, R.L.3
  • 22
    • 0023951211 scopus 로고
    • Effects of anticholinergic treatment on transient behavioral suppression and physiological responses following concussive brain injury to the rat
    • Lyeth, B. G.; Dixon, C. E.; Hamm, R. J.; Jenkins, L. W.; Young, H. F.; Stonnington, H. H.; Hayes, R. L.: Effects of anticholinergic treatment on transient behavioral suppression and physiological responses following concussive brain injury to the rat. Brain Res. 448:88-97; 1988.
    • (1988) Brain Res. , vol.448 , pp. 88-97
    • Lyeth, B.G.1    Dixon, C.E.2    Hamm, R.J.3    Jenkins, L.W.4    Young, H.F.5    Stonnington, H.H.6    Hayes, R.L.7
  • 24
    • 0025002707 scopus 로고
    • Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat
    • Lyeth, B. G.; Jenkins, L. W.; Hamm, R. J.; Dixon, C. E.; Phillips, L. L.; Clifton, G. L.; Young, H. F.; Hayes, R. L.: Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat. Brain Res. 526:249-258; 1990.
    • (1990) Brain Res. , vol.526 , pp. 249-258
    • Lyeth, B.G.1    Jenkins, L.W.2    Hamm, R.J.3    Dixon, C.E.4    Phillips, L.L.5    Clifton, G.L.6    Young, H.F.7    Hayes, R.L.8
  • 26
    • 0024913248 scopus 로고
    • Effects of N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury
    • McIntosh, T. K.; Vink, R.; Scares, H.; Hayes, R. L.; Simon, R.: Effects of N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury. J. Neurotrauma 6:247-259; 1989.
    • (1989) J. Neurotrauma , vol.6 , pp. 247-259
    • McIntosh, T.K.1    Vink, R.2    Scares, H.3    Hayes, R.L.4    Simon, R.5
  • 29
    • 0028941501 scopus 로고
    • Medicinal chemistry of muscarinic agonists: Developments since 1990
    • Moltzen, E. K.; Bjornholm, B.: Medicinal chemistry of muscarinic agonists: Developments since 1990. Drugs Future 20:37-54; 1995.
    • (1995) Drugs Future , vol.20 , pp. 37-54
    • Moltzen, E.K.1    Bjornholm, B.2
  • 30
    • 0005535917 scopus 로고
    • Spatial localization does not require the presence of local cues
    • Morris, R. G. M.: Spatial localization does not require the presence of local cues. Learn. Motiv. 12:239-260; 1981.
    • (1981) Learn. Motiv. , vol.12 , pp. 239-260
    • Morris, R.G.M.1
  • 31
    • 0021815305 scopus 로고
    • Social adjustment after closed head injury: A further follow-up seven years after injury
    • Oddy, M.; Coughlan, T.; Tyerman, A.; Jenkins, D.: Social adjustment after closed head injury: A further follow-up seven years after injury. J. Neurol. Neurosurg. Psychiatry 48:564-568; 1985.
    • (1985) J. Neurol. Neurosurg. Psychiatry , vol.48 , pp. 564-568
    • Oddy, M.1    Coughlan, T.2    Tyerman, A.3    Jenkins, D.4
  • 32
    • 0028865589 scopus 로고
    • Chronic post-injury administration of Suritozole, a negative modulator at the GABA receptor, attenuates cognitive impairment in rats following traumatic brain injury
    • O'Dell, D. M.; Hamm, R. J.: Chronic post-injury administration of Suritozole, a negative modulator at the GABA receptor, attenuates cognitive impairment in rats following traumatic brain injury. J. Neurosurg. 83:878-883; 1995.
    • (1995) J. Neurosurg. , vol.83 , pp. 878-883
    • O'Dell, D.M.1    Hamm, R.J.2
  • 33
    • 0023813452 scopus 로고
    • Pharmacological adaptations and muscarinic receptor plasticity in hypothalamus of senescent rats treated chronically with cholinergic drugs
    • Pedigo, N. W., Jr.: Pharmacological adaptations and muscarinic receptor plasticity in hypothalamus of senescent rats treated chronically with cholinergic drugs. Pharmacology 95:497-501; 1988.
    • (1988) Pharmacology , vol.95 , pp. 497-501
    • Pedigo N.W., Jr.1
  • 34
    • 0028998973 scopus 로고
    • 2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats
    • 2 receptor antagonist, improves cognitive performance following traumatic brain injury in rats. Brain Res. 686:37-43; 1995.
    • (1995) Brain Res. , vol.686 , pp. 37-43
    • Pike, B.R.1    Hamm, R.J.2
  • 35
    • 0025232365 scopus 로고
    • Activating the damaged basal forebrain cholinergic system: Tonic stimulation versus signal amplification
    • Sarter, M.; Bruno, J. P.; Dudchenko, P.: Activating the damaged basal forebrain cholinergic system: Tonic stimulation versus signal amplification. Psychopharmacology 101:1-17; 1990.
    • (1990) Psychopharmacology , vol.101 , pp. 1-17
    • Sarter, M.1    Bruno, J.P.2    Dudchenko, P.3
  • 36
    • 0029125851 scopus 로고
    • Loss of forebrain cholinergic neurons following fluid-percussion injury: Implications for cognitive impairment in closed head injury
    • Schmidt, R. H.; Grady, M. S.: Loss of forebrain cholinergic neurons following fluid-percussion injury: Implications for cognitive impairment in closed head injury. J. Neurosurg. 83:496-502; 1995.
    • (1995) J. Neurosurg. , vol.83 , pp. 496-502
    • Schmidt, R.H.1    Grady, M.S.2
  • 38
    • 0011089504 scopus 로고
    • Nerve growth factor attenuates the loss of cholinergic neurons in the medial septal nucleus which occurs after fluid-percussion brain injury in the rat
    • Sinson, G.; Flamm, E. S.; McIntosh, T. K.: Nerve growth factor attenuates the loss of cholinergic neurons in the medial septal nucleus which occurs after fluid-percussion brain injury in the rat. Soc. Neurosci. Abstr. 21:2121; 1995.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 2121
    • Sinson, G.1    Flamm, E.S.2    McIntosh, T.K.3
  • 39
    • 0026324444 scopus 로고
    • Evaluation of memory dysfunction following experimental brain injury using the Morris water maze
    • Smith, D. H.; Okiyama, K.; Thomas, M. J.; Claussen, B.; McIntosh, T. K.: Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. J. Neurotrauma 8:259-269; 1991.
    • (1991) J. Neurotrauma , vol.8 , pp. 259-269
    • Smith, D.H.1    Okiyama, K.2    Thomas, M.J.3    Claussen, B.4    McIntosh, T.K.5
  • 40
    • 0027132491 scopus 로고
    • Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury
    • Smith, D. H.; Okiyama, K.; Thomas, M. J.; McIntosh, T. K.: Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury. J. Neurosci. 13:5383-5392; 1993.
    • (1993) J. Neurosci. , vol.13 , pp. 5383-5392
    • Smith, D.H.1    Okiyama, K.2    Thomas, M.J.3    McIntosh, T.K.4
  • 41
    • 0001130441 scopus 로고
    • Acetylcholine
    • Seigel, G. J.; Agranoff, B. W.; Albers, R. W.; Molinoff, P. B., eds. New York: Raven Press
    • Taylor, P.; Brown, J. H.: Acetylcholine. In: Seigel, G. J.; Agranoff, B. W.; Albers, R. W.; Molinoff, P. B., eds. Basic neurochemistry. New York: Raven Press; 1994:231-260.
    • (1994) Basic Neurochemistry , pp. 231-260
    • Taylor, P.1    Brown, J.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.