Expression and function of the early activation antigen CD69 in murine macrophages

Journal of Leukocyte Biology

Volumn 62, Issue 3, 1997, Pages 349-355

  Marzio, Rosa ^a,b   Jirillo, Emilio ^b   Ransijn, Adriana ^a   Mauël, Jacques ^a   Corradin, Sally Betz ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

Flow cytometry; Intracellular killing; Leishmania; Lipopolysaccharide; Nitric oxide; Tumor necrosis factor

Indexed keywords

CD69 ANTIGEN; GAMMA INTERFERON; MONOCLONAL ANTIBODY; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; LEISHMANIASIS; LYMPHOCYTE ACTIVATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE; PROTOZOA;

EID: 0030873603     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.62.3.349     Document Type: Article

References (37)

1. Green, S. J., Nacy, C. A., Meltzer, M. S. (1991) Cytokine-induced synthesis of nitrogen oxides in macrophages: a protective host response to Leishmania and other intracellutar pathogens. J. Leukoc. Biol. 50, 93-103.
2. Green, S. J., Meltzer, M. S., Hibbs, J. B., Nacy, C. A. (1990) Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J. Immunol. 144, 278-283.
3. Liew, F. Y., Millot, S., Parkinson, C., Palmer, R. M. J., Moncada, S. (1990) Macrophage killing of Leishmania parasites in vivo is mediated by nitric oxide from L-arginine. J. Immunol. 144, 4794-4797.
4. Mauël, J., Ransijn, A., Buchmüller-Rouiller, Y. (1991) Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives. J. Leukoc. Biol. 49, 73-82.
5. Hara, T., Jung, L. K. L., Bjorndahl, J. M., Fu, S. M. (1986) Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigen. J. Exp. Med. 164, 1988-2005.
6. Cosulich, M. E., Rubartelli, A., Risso, A., Cozzolino, F., Bargellesi, A. (1987) Functional characterization of new antigen involved in an early step of T cell activation. Proc. Natl. Acad. Sci. USA 84, 4205-4209.
7. Cebrian, M., Yagüe, E., Rincon, M., Lopez-Botet, M., De Landazuri, M. O., Sanchez-Madrid, F. (1988) Triggering of T cell proliferation through AIM, an activation induced molecule expressed on activated human lymphocytes. J. Exp. Med. 168, 1621-1637.
8. Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M. B., Stingl, G., Coligan, J. E., Shevach, E. M. (1988) Characterization of a cell surface expressed disulfide-linked dimer involved in murine T cell activation. J. Immunol. 141, 369-376.
9. Hamann, J., Fiebig, H., Strauss, M. (1993) Expression cloning of the early activation antigen CD69, a type II integral membrane protein with a C-type lectin domain. J. Immunol. 150, 4920-4927.
10. López-Cabrera, M., Santis, A. G., Fernández-Ruiz, E., Blacher, R., Esch, F., Sánchez-Mateos, P., Sánchez-Madrid, F. (1993) Molecular cloning, expression and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal transducing receptors. J. Exp. Med. 178, 537-547.
11. Ziegler, S. F., Ramsdell, F., Hjerrild, K. A., Armitage, R. J., Grabstein, K. H., Hennen, K. B., Farrah, T., Fanslow, W. C., Shevach, E. M., Alderson, M. R. (1993) Molecular characterization of the early activation antigen CD69: a member of the NKR-P1 family of the type II membrane glycoproteins. Eur. J. Immunol. 23, 1643-1648.
12. Testi, R., D'Ambrosio, D., De Maria, R., Santoni, A. (1994) The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. Immunol. Today 15, 479-483.
13. Testi, R., Pulcinelli, F. L., Frati, L., Gazzaniga, P. P., Santoni, A. (1990) CD69 is expressed on platelets and mediates platelet activation and aggregation. J. Exp. Med. 172, 701-707.
14. Bieber, T., Rieger, A., Stingl, G. Sander, E., Wanek, P., Strober, I. (1992) CD69, an early activation antigen on lymphocytes, is constitutively expressed by human epidermal Langerhans cells. J. Invest. Dermatol. 98, 771-776.
15. bright human thymocytes. J. Immunol. 141, 2557-2563.
16. ++] and activation of PKC. J. Immunol. 142, 1854-1860.
17. Lanier, L. L., Buck, D. W., Rhodes, L., Ding, A., Evans, E., Barney, C., Phillips, J. H. (1988) Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen. J. Exp. Med. 167, 1572-1585.
18. Gerosa, F., Scardoni, M., Tommasi, M., Benati, C., Snelli, L., Gandini, G., Libonati, M., Tridente, G., Carra, G. (1991) Interferon alpha induces expression of the CD69 activation antigen in human resting NK cells, while interferon gamma and tumor necrosis factor are ineffective. Int. J. Cancer 48, 473-475.
19. Gavioli, R., Risso, A., Smilovich, D., Baldissarro, I., Capra, M. C., Bargellesi, A., Cosulich, E. (1992) CD69 molecule in human neutrophils: its expression and role in signal-transducing mechanisms. Cell. Immunol. 142, 186-196.
20. Hartnell, A., Robinson, D. S., Kay, A. B., Wardlaw, A. J. (1993) CD69 is expressed by human eosinophils activated in vivo in asthma and in vitro by cytokines. Immunology 80, 281-286.
21. De Maria, R., Cifone, M. G., Trotta, R., Rippo, M. R., Festuccia, C., Santoni, A., Testi, R. (1994) Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. J. Exp. Med. 180, 1999-2004.
22. Vouldoukis, I., Riveros-Moreno, V., Dugas, B., Ouaaz, F., Bécherel, P., Debré, P., Moncada, S., Mossalayi, M. D. (1995) The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the FcεRII/CD23 surface antigen. Proc. Natl. Acad. Sci. USA 92, 7804-7808.
23. Eugster, H.-P., Müller, M., Karrer, U., Car, B. D., Schnyder, B., Eng, V. M., Woerly, G., Le Hir, M., Di Padova, F., Aguet, M., Zinkernagel, R., Buethmann, H., Ryffel, B. (1996) Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double deficient mice. Int. Immunol. 8, 23-36.
24. Meerpohl, H.-G., Lohmann-Matthes, M. L., Fischer, H. (1976) Studies on the activation of mouse bone marrow-derived macrophages by the macrophage cytotoxicity factor. Eur. J. Immunol. 6, 213-217.
25. Mauël, J. (1984) Intracellular parasite killing induced by electron carriers. I. Effect of electron carriers on intracellular Leishmania spp. in macrophages from different genetic backgrounds. Mol. Biochem. Parasitol. 13, 83-96.
26. Ding, A. H., Nathan, C. F., Stuehr, D. J. (1988) Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J. Immunol. 141, 2407-2412.
27. Espevik, T., Nissen-Meyer, J. (1986) A highly sensitive cell line, WEHI clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Meth. 95, 99-105.
28. Betz Corradin, S., Mauël, J. (1991) Phagocytosis of Leishmania enhances macrophage activation by IFN-γ and lipopolysaccharide. J. Immunol. 146, 279-285.
29. Green, S. J., Crawford, R. M., Hockmeyer, J. T., Meltzer, M. S., Nacy, C. A. (1990) Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of TNF-α. J. Immunol. 145, 4290-4297.
30. Betz Corradin, S., Buchmüller-Rouiller, Y., Mauël, J. (1991) Phagocytosis enhances murine macrophage activation by interferon-γ and tumor necrosis factor-α. Eur. J. Immunol. 21, 2553-2558.
31. 2 and of agents that raise cAMP levels on macrophage activation induced by IFN-γ and TNF. J. Leukoc. Biol. 58, 217-224.
32. Buchmüller-Rouiller, Y., Betz Corradin, S., Mauël, J. (1992) Differential effects of prostaglandins on macrophage activation induced by calcium ionophore A23187 or interferon-gamma. J. Immunol. 148, 1171-1175.
33. Drapier, J. C., Wietzerbin, G., Hibbs, J. B. (1988) Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. 18, 1587-1592.
34. López-Cabrera, M., Muñoz, E., Valle Blázquez, M., Ursa, M. A., Santis, A. G., Sánchez-Madrid, F. (1995) Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-α-responsive elements. J. Biol. Chem. 270, 21221-21545.
35. Ziegler, S. F., Levin, S. D., Johnson, L., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Baker, E., Sutherland, G. R., Feldhaus, A. L., Ramsdell, F. (1994) The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex. J. Immunol. 152, 1228-1236.
36. Risso, A., Smilovich, D., Capra, M. C., Baldissarro, I., Yan, G., Bargellesi, A., Cosulich, M. E. (1991) CD69 in resting and activated T lymphocytes. Its association with a GTP binding protein and biochemical requirements for its expression. J. Immunol. 146, 4105-4114.
37. Santis, A. G., Campanero, M. R., Alonso, J. L., Tugores, A., Alonso, M. A., Yagúe, E., Pivel, J. P., Sánchez-Madrid, F. (1992) Tumor necrosis factor-α production induced in T lymphocytes through the AIM/CD69 activation pathway. Eur. J. Immunol. 22, 1253-1259.