Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

Nature Biotechnology

Volumn 15, Issue 7, 1997, Pages 641-646

  Kirn, Jong J ^a   Bagarazzi, Mark L ^a   Trivedi, Neil ^a   Hu, Yin ^b   Kazahaya, Ken ^b   Wilson, Darren M ^a   Ciccarelli, Richard ^c   Chattergoon, Michael A ^a   Dang, Kesan ^a   Mahalingam, Sundarasamy ^a   Chalian, Ara A ^b   Agadjanyan, Michael G ^a   Boyer, Jean D ^a   Wang, Bin ^a   Weiner, David B ^a  

^a Department of Chemical Engineering ^*  (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Apollon Inc   (United States)

Author keywords

Costimulatory molecules; DNA vaccines; Immune responses

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; CELL SURFACE MARKER; NUCLEIC ACID; PLASMID DNA; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIBODY FORMATION; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, CD86; BASE SEQUENCE; BIOTECHNOLOGY; DNA PRIMERS; HUMANS; IMMUNIZATION; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; PROTEIN ENGINEERING; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER; VACCINES, DNA;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030873202     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0797-641     Document Type: Article

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