Probing Flp: A new approach to analyze the structure of a DNA recognizing protein by combining the genetic algorithm, mutagenesis and non-canonical DNA target sites

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1340, Issue 2, 1997, Pages 187-204

  Saxena, Pratibha ^a   Whang, Ilson ^a   Voziyanov, Yuri ^a   Harkey, Cecil ^a   Argos, Patrick ^b   Jayaram, Makkuni ^a   Dandekar, Thomas ^b  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

DNA recombinase; Flp; Genetic algorithm; Structure function relationship

Indexed keywords

DNA BINDING PROTEIN; RECOMBINASE;

ALGORITHM; ARTICLE; BINDING SITE; COMPUTER SIMULATION; DNA BINDING; HYDROGEN BOND; INTERMETHOD COMPARISON; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; TECHNIQUE;

BINDING SITES; DNA NUCLEOTIDYLTRANSFERASES; DNA, FUNGAL; MODELS, MOLECULAR; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

SACCHAROMYCES CEREVISIAE;

EID: 0030873058     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(97)00017-4     Document Type: Article

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