The anovulation in female mice resulting from postnatal injections of estrogen is correlated with altered levels of CD8+ lymphocytes

American Journal of Reproductive Immunology

Volumn 38, Issue 2, 1997, Pages 114-120

  Deshpande, Rohini R ^a   Chapman, John C ^a   Michael, Sandra D ^a  

^a BINGHAMTON UNIVERSITY   (United States)

Author keywords

CD4+ CD8+ lymphocyte ratio; Corpora lutea; Ovarian function; Steroid induced sterility

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; ESTRADIOL; ESTROGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOVULATION; ARTICLE; CELL MATURATION; CONTROLLED STUDY; CORPUS LUTEUM; FEMALE; HISTOLOGY; MOUSE; NONHUMAN; OVARY; PERINATAL PERIOD; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

EID: 0030872971     PISSN: 87558920     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0897.1997.tb00285.x     Document Type: Article

References (45)

1. Barraclough CA, Leathem JH. Infertility induced in mice by a single injection of testosterone propionate. Proc Soc Exp Biol Med 1954; 85:673-674.
2. Barraclough CA. Production of anovulatory, sterile rats by single injections of testosterone propionate. Endocrinology 1962; 68:62-67.
3. Gorski RA. Modification of ovulatory mechanisms by post- natal administration of estrogen to the rat. Am J Physiol 1963; 205:842-844.
4. Gorski RA, Barraclough CA. Effects of low dosages of androgen on the differentiation of hypothalamic regulatory control of ovulation in the rat. Endocrinology 1963; 73: 210-216.
5. Barraclough CA, Gorski RA. Evidence that the hypothalamus is responsible for androgen-induced sterility in the female rat. Endocrinology 1961; 68:68-79.
6. Gorski RA. Steroid-induced sexual characteristics in the brain. In Neuroendocrine Function, Vol. 2, EE Muller, RM MacLeod (eds). Amsterdam, Elsevier, 1983, pp 1-35.
7. Gorski RA. Sexual differentiation of the brain: Comparative aspects. In Control of the onset of puberty, MM Grumbach, PC Sizonenko, ML Aubert (eds). Baltimore, Williams and Wilkins, 1990, pp 231-250.
8. Naftolin F, Garcia-Segura LM, Feefe D, Leranth C, Maclusky NJ, Brawer JR. Estrogen effects on the synaptology and neural membranes of the rat hypothalamic arcuate nucleus. Biol Reprod 1990; 42:21-26.
9. Kubo K, Mennin SP, Gorski RA. Similarity of plasma LH release in androgenized and normal rats following electricochemical stimulation of the basal forebrain. Endocrinology 1975; 96:492-500.
10. Kalland TK. Decreased and disproportionate T-cell population in adult mice after neonatal exposure to diethylstilbestrol. Cellular Immunol 1980; 51:55-63.
11. Kovacs WJ, Olsen NJ. 1987 Androgen receptors in human thymocytes. J Immunol 139:490-493.
12. Kincl FA, Oriol A, Folch Pi A, Maqueo M. Prevention of steroid-induced sterility in neonatal rats with thymic cell suspension. Proc Soc Exp Biol Med 1965; 120:252-253.
13. Mayer G, Duluc AJ. Reactions of the postnatal ovary after transplantation into castrated normal and sterilized rats. In WR Butt, AC Crooke, M Ryle (eds). Gonadotrophins and ovarian development; Proceedings of the two Workshop Meetings on the Chemistry of the Human Infancy, Birmingham, 1969. Baltimore, Williams & Wilkens, 1970, pp 332-336.
14. Brannstrom M, Mayrhofer G, Robertson SA. Localization of leukocyte subsets in the rat ovary during the periovulatory period. Biol Reprod 1993; 48:277-286.
15. Brannstrom M, Giesecke L, Moore IC, Van den Heuval CJ, Robertson SA. Leukocyte subpopulations in the rat corpus luteum during pregnancy and pseudopregnancy. Biol Reprod 1994; 50:1161-1167.
16. Novotny EA, Raveche ES, Sharrow S, Ottinger M, Steinberg AD. Analysis of thymocyte subpopulations following treatment with sex hormones. Clin Immunol Immunopathol 1983; 28:205-217.
17. Ahmed SA, Dauphinee MJ, Talal N. Effects of short-term administration of sex hormones on normal and autoimmune mice. J Immunol 1985; 134:204-210.
18. Grossman CJ. Bidirectional communication between the immune and endocrine systems: Sex steroid influence on thymic lymphocytes. Am J Reprod Immunol 1992; 27:21-33.
19. Ho PC, Tang GWK, Fu KH, Fan MC, Lawton JWM. Immunologic studies in patients with premature ovarian failure. Obstet Gynecol 1988; 71:622-626.
20. Ho PC, Tang GWK, Lawton JWM. Lymphocyte subsets in patients with oestrogen deficiency. J Reprod Immunol 1991; 20:85-91.
21. Bromberg JS, Chavin KD, Altevogt P, Kyewski BA, Guckel B, Naji A, Barker CF. Anti-CD2 monoclonal antibodies alter cell-mediated immunity in vivo. Transplantation 1991; 51:219-225.
22. Gorski, RA. Influence of age on the response to paranatal administration of a low dose of androgen. Endocrinology 1968; 82:1001-1004.
23. Swanson HE, van der Werff ten Bosch JJ. The early androgen syndrome: Its development and response to hemi-spaying. Acta Endocrinol 1964; 45:1-12.
24. Husmann LA, Shimonkevitz RP, Crispe IN, Bevan MJ. Thymocyte subpopulations during early fetal life in the BALB/c mouse. J Immunol 1988; 141:736-740.
25. McLachlan JA, Newbold RR, Shah H, Hogan MD, Dixon RL. Reduced fertility in female mice exposed transplacentally to diethylstilbestrol (DES). Fertil Steril 1982; 38:364-371.
26. Halling A, Forsberg J-G. Ovarian reproductive function after exposure to diethylstilbestrol in neonatal life. Biol Reprod. 1990; 43:472-477.
27. Swanson HE, van der Werff ten Bosch JJ. The early androgen syndrome: differences in response to prenatal and postnatal administration of various doses of testosterone proprionate in female and male rats. Acta Endocrinol 1964; 47:37-50.
28. Grossman CJ. Interactions between the gonadal steroids and the immune system. Science. 1985; 227:257-261.
29. Szekeres-Bartho J, Reznikoff-Etievant MF, Varga P, Pichon MF, Varga T, Chaouat G. Lymphocytic progesterone receptors in human pregnancy. J Reprod Immunol 1989; 16: 239-244.
30. Utsuyama M, Hirokawa K. Hypertrophy of the thymus and restoration of immune functions in mice and rats by gonadectomy. Mech Ageing Dev 1989; 47:175-185.
31. Bukovsky A, Presl J, Krabec Z, Bednarik T. Ovarian function in rats treated with antithymocyte serum. Experimentia 1977; 33:280-281.
32. Alila HW, Hansel W. Induction of lymphopenia causes luteal dysfunction in cattle. Biol Reprod 1984; 31:671-678.
33. Grasso G, Muscettola M. Possible role of interferon-gamma in ovarian function. Ann N Y Acad Sci 1992; 50:191.
34. Hill JA, Barbieri RL, Anderson DJ. Detection of T8 (suppressor/cytotoxic) lymphocytes in human ovarian follicular fluid. Fertil Steril 1986; 47:114.
35. Hellberg P, Thomsen P, Janson PO, Brannstrom M. Leukocyte supplementation increases the luteinizing hormone-induced ovulation rate in the in vitro-perfused rat ovary. Biol Reprod 1991;44:791-797.
36. Brannstrom M, Wang L, Norman RJ. Ovulatory effect of interleukin-1 on the perfused rat ovary. Endocrinology. 1993; 132:399-405.
37. Cohen JHM, Danel L, Cordier G, Saez S, Revillard J-P. Sex steroid receptors in peripheral T cells: absence of androgen receptors and restriction of estrogen receptors to OKT-8 positive cells. J Immunol 1983; 131:2767-2771.
38. Stimson WH. Oestrogen and human T lymphocytes: Presence of specific receptors in the T-suppressor/cytotoxic subset. Scand J Immunol 1988; 28:345-348.
39. McNatty KP, Smith DM, Makris A, Osathanondh R, Ryan KJ. The microenvironment of the human antral follicle: Interrelationships among the steroid levels in antral fluid, the population of granulosa cells, and the status of the oocyte in vivo and in vitro. J Clin Endocrinol Metab 1979; 49: 851-860.
40. Fox HS, Bond BL, Parslow TG. Estrogen regulates the IFN-γ promoter. J Immunol 1991; 146:4362-4367.
41. Espevik T, Figari IS, Shalaby MR, Lackides GA, Lewis GD, Shepard HM, Palladino MA Jr. Inhibition of cytokine production by cyclosporin A and transforming growth factor. J Exp Med 1987; 166:571-576.
42. Al-Chalabi HA. Effect of cyclosporin A on the morphology and function of the ovary and fertility in the rabbit. Int J Fertil 1984; 29:218-223.
43. Bukovsky A, Presl J, Holub M. The ovarian follicle as a model for the cell-mediated control of tissue growth. Cell Tissue Res 1984; 236:717-724.
44. + cells in ovarian function. Biol Reprod 1986; 34:159-169.
45. Petrovska M, Dimitrov DG, Michael SD. Quantitative changes in macrophage distribution in normal mouse ovary over the course of the estrous cycle examined with an image analysis system. Am J Reprod Immunol 1996; 36: 175-183.