Platelet aggregation in patients bitten by the brazilian snake Bothrops jararaca

Thrombosis Research

Volumn 87, Issue 2, 1997, Pages 183-195

  Sano Martins, Ida S ^a   Santoro, Marcelo L ^a   Castro, Sandra C B ^a   Fan, Hui W ^a   Cardoso, João L C ^a   Theakston, R David G ^b  

^a INSTITUTO BUTANTAN   (Brazil)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

Platelet aggregation; Platelet function tests; Snake bites; Snake venoms

Indexed keywords

ARTICLE; BLEEDING; BLEEDING DISORDER; BLEEDING TIME; BRAZIL; ENVENOMATION; FIBRINOLYSIS; HEMOSTASIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SNAKEBITE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

ADOLESCENT; ADULT; AGED; ANIMALS; BOTHROPS; CROTALID VENOMS; FEMALE; HUMANS; MALE; MIDDLE AGED; PLATELET AGGREGATION; SNAKE BITES;

EID: 0030872664     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(97)00118-7     Document Type: Article

References (47)

1. GEORGE J.N., SHATTIL S.J. The clinical importance of acquired abnormalities of platelet function. N England J Med. 324:1991;27-39.
2. BRASIL. Relatório de Atividades. Ministério da Saúde, Fundação Nacional da Saúde, Centro Nacional de Epidemiologia, Brasília, Mimeo, 1994.
3. RIBEIRO L.A., JORGE M.T. Epidemiologia e quadro clínico dos acidentes por serpentes Bothrops jararaca adultas e filhotes. Rev Inst Med Trop São Paulo. 32:1990;436-442.
4. CARDOSO J.L.C., FAN H.W., FRANÇA F.O.S., JORGE M.T., LEITE R.P., NISHIOKA S.A., AVILA A., SANO-MARTINS I.S., TOMY S.C., SANTORO M.L., CHUDZINSKI A.M., CASTRO S.C.B., KAMIGUTI A.S., KELEN E.M.A., HIRATA M.H., MIRANDOLA R.M.S., THEAKSTON R.D.G., WARRELL D.A. Randomized comparative trial of three antivenoms in the treatment of envenoming by lance-headed vipers (Bothrops jararaca) in São Paulo, Brazil. Q J Med. 86:1993;315-325.
5. KAMIGUTI A.S., CARDOSO J.L.C., THEAKSTON R.D.G., SANO-MARTINS I.S., HUTTON R.A., RUGMAN F.P., WARRELL D.A., HAY C.R.M. Coagulopathy and haemorrhage in human victims of Bothrops jararaca envenoming in Brazil. Toxicon. 29:1991;961-972.
6. KAMIGUTI A.S., RUGMAN F.P., THEAKSTON R.D.G., FRANÇA F.O.S., ISHII H., HAY C.R.M., BIASG The role of venom haemorrhagin in spontaneous bleeding in Bothrops jararaca envenoming. Thromb Haemost. 67:1992;484-488.
7. NAHAS L., KAMIGUTI A.S., RZEPPA H.W., SANO I.S., MATSUNAGA S. Effect of heparin on the coagulant action of snake venoms. Toxicon. 13:1975;457-463.
8. KAMIGUTI A.S., MATSUNAGA S., SPIR M., SANO-MARTINS I.S., NAHAS L. Alterations of the blood coagulation system after accidental human inoculation by Bothrops jararaca venom. Braz J Med Biol Res. 19:1986;199-204.
9. MARUYAMA M., KAMIGUTI A.S., CARDOSO J.L.C., SANO-MARTINS I.S., CHUDZINSKI A.M., SANTORO M.L., MORENA P., TOMY S.C., ANTONIO L.C., MIHARA H., KELEN E.M.A. Studies on blood coagulation and fibrinolysis in patients bitten by Bothrops jararaca (jararaca). Thromb Haemost. 63:1990;449-453.
10. BIRAN H., STERN J., DVILANSKY A. Impaired platelet aggregation after Echis colorata bite in man. Israel J Med Sci. 8:1972;1757.
11. BIRAN H., DVILANSKY A., NATHAN I., LIVNE A. Impairment of human platelet aggregation and serotonin release caused in vitro by Echis colorata venom. Thromb Diath Haemorrh. 30:1973;191-198.
12. KOSUGI T., MIYAGI T., SHIMA Y., NAKAMURA M. Changes of fibrinogen and platelet function in rabbits following administration of Trimeresurus flavoviridis venom. Snake. 21:1989;9-17.
13. THAN-T., HUTTON R.A., MYINT-L., KHIN-E.-H., SOE-S., TIN-N.-S., PHILLIPS R.E., WARRELL D.A. Haemostatic disturbances in patients bitten by Russell's viper (Vipera russelli siamensis) in Burma. Br J Haematol. 69:1988;513-520.
14. HUTTON R.A., LOOAREESUWAN S., HO M., SILAMUT K., CHANTHAVANICH P., KARBWANG J., SUPANARANOND W., VEJCHO S., VIRAVAN C., PHILLIPS R.E., WARRELL D.A. Arboreal green pit vipers (genus Trimeresurus) of south-east Asia: bites by T. albolabris and T. macrops in Thailand and a review of the literature. Trans Royal Soc Trop Med Hyg. 84:1990;866-874.
15. SANTORO, M.L. Alterações morfofuncionais plaquetárias após envenenamento experimental por Bothrops jararaca em coelhos [Morphological and functional disturbances of blood platelets following experimental Bothrops jararaca envenomation in rabbits]. College of Pharmacy, University of São Paulo, São Paulo, 1993. [Dissertation for Master Degree].
16. SANTORO M.L., SANO-MARTINS I.S. Different clotting mechanisms of Bothrops jararaca snake venom on human and rabbit plasmas. Toxicon. 31:1993;733-742.
17. SÃO PAULO. Acidentes por animais peçonhentos. Identificação, diagnóstico e tratamento. Secretaria do Estado da Saúde, São Paulo, 1993. 61 p.
18. SANTORO M.L., SANO-MARTINS I.S., CHAMONE D.A.F. In vivo platelet activation induced by Bothrops jararaca venom in rabbits. Platelets. 5:1994;162-170.
19. CARDINAL D.C., FLOWER R.J. The electronic aggregometer: a novel device for assessing platelet behavior in blood. J Pharmacol Meth. 3:1980;135-158.
20. BORN G.V.R. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature. 194:1962;927-929.
21. RATNOFF O.D., MENZIE C. A new method for the determination of fibrinogen in small samples of plasma. J Lab Clin Med. 37:1951;316-320.
22. MUSTARD J.F., KINLOUGH-RATHBONE R.L., PACKHAM M.A. Isolation of human platelets from plasma by centrifugation and washing. Methods Enzymol. 169:1989;3-11.
23. KINLOUGH-RATHBONE, R.L.; PACKHAM, M.A. and MUSTARD, J.F. Platelet Aggregation. In: Measurements of Platelet function. Harker, L.A. and Zimmerman, T.S. (eds.), pp 64-91, Churchill Livingstone, New York, 1983.
24. DACIE, J.V. and LEWIS, S.M. Reference ranges and normal values. In: Practical Haematology. Dacie, J.V. and Lewis, S.M. (eds.), pp 9-17, Churchill Livingstone, Edinburgh, 1991.
25. KAMIGUTI A.S., SANO-MARTINS I.S. South-American snake venoms affecting haemostasis. J Toxicol Toxin Rev. 14:1995;359-374.
26. SERRANO S.M.T., MENTELE R., SAMPAIO C.A.M., FINK E. Purification, characterization, and amino acid sequence of a serine proteinase, PA-BJ, with platelet-aggregating activity from the venom of Bothrops jararaca. Biochemistry. 34:1995;7186-7193.
27. FUJIMURA Y., TITANI K., USAMI Y., SUZUKI M., OYAMA R., MATSUI T., FUKUI H., SUGIMOTO M., RUGGERI Z.M. Isolation and chemical characterization of two structurally and functionally distinct forms of botrocetin, the platelet coagglutinin isolated from the venom of Bothrops jararaca. Biochemistry. 30:1991;1957-1964.
28. SCARBOROUGH R.M., ROSE J.W., NAUGHTON M.A., PHILLIPS D.R., NANNIZZI L., ARFSTEN A., CAMPBELL A.M., CHARO I.F. Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms. J Biol Chem. 268:1993;1058-1065.
29. ZINGALI R.B., CARLINI C.R., FRANCISCHETTI I.M., GUIMARÃES J.A. Bothrops jararaca snake venom: effects on platelet aggregation. Thromb Res. 58:1990;303-316.
30. USAMI Y., FUJIMURA Y., MIURA S., SHIMA H., YOSHIDA E., YOSHIOKA A., HIRANO K., SUZUKI M., TITANI K. A 28 kDa-protein with disintegrin-like structure (jararhagin-C) purified from Bothrops jararaca venom inhibits collagen- and ADP-induced platelet aggregation. Biochem Biophys Res Commun. 201:1994;331-339.
31. FUJIMURA Y., IKEDA Y., MIURA S., YOSHIDA E., SHIMA H., NISHIDA S., SUZUKI M., TITANI K., TANIUCHI Y., KAWASAKI T. Isolation and characterization of jararaca GPIb-BP, a snake venom antagonist specific to platelet glycoprotein Ib. Thromb Haemost. 74:1995;743-750.
32. SMITH J.B., DANGELMAIER C., SELAK M. Identification of 50kDa snake venom proteins which specifically inhibit platelet adhesion to collagen. FEBS Lett. 283:1991;307-310.
33. NISHIDA S., FUJIMURA Y., MIURA S., OZAKI Y., USAMI Y., SUZUKI M., TITANI K., YOSHIDA E., SUGIMOTO M., YOSHIOKA A., FUKUI H. Purification and characterization of bothrombin, a fibrinogen-clotting serine protease from the venom of Bothrops jararaca. Biochemistry. 33:1994;1843-1849.
34. ZINGALI R.B., JANDROT-PERRUS M, GUILLIN M.C., BON C. Bothrojaracin, a new thrombin inhibitor from Bothrops jararaca venom: characterization and mechanism of thrombin inhibition. Biochemistry. 32:1993;10794-10802.
35. KOWALSKI E., BUDZYNSKI A.Z., KOPEC M., LATALLO Z.S., LIPINSKI B., WEGRZYNOWICZ Z. Studies on the molecular pathology and pathogenesis of bleeding in severe fibrinolytic states in dogs. Thromb Diath Haemorrh. 12:1964;69-86.
36. PASQUA J.J., PIZZO S.V. The role of ligand-ligand interactions in competition by fibrinogen and fibrin degradation products for fibrinogen binding to human platelets. Biochim Biophys Acta. 757:1983;282-287.
37. RUCINSKI B., NIEWIAROWSKI S., HOLT J.C., SOSZKA T., KNUDSEN K.A. Batroxostatin, an Arg-Gly-Asp-containing peptide from Bothrops atrox, is a potent inhibitor of platelet aggregation and cell interaction with fibronectin. Biochim Biophys Acta. 1054:1990;257-262.
38. IUAN F.C., THOMAZINI I.A., CARVALHO I., CARREIRA D.M.G., CASSINELLI V.J., PEREIRA P.C.M., BARRAVIERA B. Evaluation of platelet number and function and fibrinogen level in patients bitten by snakes of the Bothrops genus. Rev Soc Bras Med Trop. 28:1995;19-24.
39. MACKIE I.J., JONES R., MACHIN S.J. Platelet impedance aggregation in whole blood and its inhibition by antiplatelet drugs. J Clin Pathol. 37:1984;874-878.
40. KAMIGUTI A.S., THEAKSTON R.D.G., DESMOND H., HUTTON R.A. Systemic haemorrhage in rats induced by a haemorrhagic fraction from Bothrops jararaca venom. Toxicon. 29:1991;1097-1105.
41. KAMIGUTI A.S., HAY C.R.M., THEAKSTON R.D.G., ZUZEL M. Insights into the mechanism of haemorrhage caused by snake venom proteinases. Toxicon. 34:1996;627-642.
42. ABBATE R., BODDI M., PRISCO D., GENSINI G.F. Ability of whole blood aggregometer to detect platelet hyperaggregability. Am J Clin Pathol. 91:1989;159-164.
43. KURATA M., ISHIZUKA N., MATSUZAWA M., HARUTA K., TAKEDA K. A comparative study of whole-blood platelet aggregation in laboratory animals: its species differences and comparison with turbidimetric method. Comp Biochem Physiol. 112C:1995;359-365.
44. GORDGE M.P., DODD N.J., RYLANCE P.B., WESTON M.J. An assessment of whole blood impedance aggregometry using blood from normal subjects and hemodialysis patients. Thromb Res. 36:1984;17-27.
45. BAZZONI G., DEJANA E., DEL MASCHIO A. Platelet-neutrophil interactions. Possible relevance in the pathogenesis of thrombosis and inflammation. Haematologica. 76:1991;491-499.
46. VALLES J., SANTOS M.T., AZNAR J., MARCUS A.J., MARTINEZ-SALES V., PORTOLES M., BROEKMAN M.J., SAFIER L.B. Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment. Blood. 78:1991;154-162.
47. KAMIGUTI, A.S.; ANTONIO, L.C. and MARIANO, M. Coagulant activity of the venom of mature and immature snakes (Bothrops jararaca) on the blood of some mammals. In: Progress in Venom and Toxin Research. Gopalakrishnakone, P. and Tan, C.K. (eds.), pp. 296-304, National University of Singapore, Singapore, 1987.