Deletion of the Bacillus subtilis isocitrate dehydrogenase gene causes a block at stage I of sporulation

Journal of Bacteriology

Volumn 179, Issue 15, 1997, Pages 4725-4732

  Jin, Shengfang ^a,c   Levin, Petra Anne ^b   Matsuno, Kiyoshi ^a   Grossman, Alan D ^b   Sonenshein, Abraham L ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c TKT Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOCITRATE DEHYDROGENASE; TRANSCRIPTION FACTOR;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; BACTERIUM MUTANT; CONTROLLED STUDY; GENE DELETION; NONHUMAN; PRIORITY JOURNAL; SPOROGENESIS;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); BACTERIUM SUBTILIS; ESCHERICHIA COLI;

EID: 0030872429     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.179.15.4725-4732.1997     Document Type: Article

References (48)

1. Alper, S. L. Duncan, and R. Losick. 1994. An adenosine nucleotide switch controlling the activity of a cell type-specific transcription factor in B. subtilis. Cell 77:195-205.
2. Burbulys, D., K. A. Trach, and J. A. Hoch. 1991. Initiation of sporulation in B. subtilis is controlled by a multicomponent phosphorelay. Cell 64:545-552.
3. K processing in Bacillus subtilis. Genes Dev. 5:456-466.
4. D'Souza, C., M. M. Nakano, and P. Zuber. 1994. Identification of comS, a gene of the srfA operon that regulates the establishment of competence in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 91:9397-9401.
5. F from Bacillus subtilis. Proc. Natl. Acad. Sci. USA 90:2325-2329.
6. Errington, J. 1993. Bacillus subtilis sporulation: regulation of gene expression and control of morphogenesis. Microbiol. Rev. 57:1-33.
7. Fort, P., and P. J. Piggot. 1984. Nucleotide sequence of the sporulation locus spoIIA in Bacillus subtilis. J. Gen. Microbiol. 130:2147-2153.
8. Fortnagel, P., and E. Freese. 1968. Analysis of sporulation mutants. II. Mutants blocked in the citric acid cycle. J. Bacteriol. 95:1431-1438.
9. Fouet, A., and A. L. Sonenshein. 1990. A target for carbon source-dependent negative regulation of the citB promoter of Bacillus subtilis. J. Bacteriol. 172:835-844.
10. Freese, E., and C. L. Marks. 1973. Developmental block in citric acid mutants of Bacillus subtilis. J. Bacteriol. 116:1466-1468.
11. Freese, E., P. Fortnagel, R. Schmitt, W. Klofat, E. Chappelle, and G. Picciolo. 1969. Biochemical genetics of initial sporulation stages, p. 82-101. In L. L. Campbell (ed.), Spores IV. American Society for Microbiol., Bethesda, Md.
12. Grossman, A. D. 1991. Integration of developmental signals and the initiation of sporulation in B. subtilis. Cell 65:5-8.
13. Grossman, A. D. 1995. Genetic networks controlling the initiation of sporulation and the development of competence in Bacillus subtilis. Annu. Rev. Genet. 29:477-508.
14. Hamoen, L. W., H. Eshuis, J. Jongboed, G. Venema, and U. van Sinderen. 1995. A small gene, designated comS, located within the coding region of the fourth amino acid-activating domain of srfA, is required for competence development. Mol. Microhiol. 15:55-63.
15. Harry, E. J., K. Pogliano, and R. Losick. 1995. Use of immunofluorescence to visualize cell-specific gene expression during sporulation in Bacillus subtilis. J. Bacteriol. 177:3386-3393.
16. Hederstedt, L. 1993. The Krebs citric acid cycle, p. 181-197. In A. L. Sonenshein, J. A. Hoch, and R. Losick (ed.), Bacillus subtilis and other gram-positive bacteria: biochemistry, physiology, and molecular genetics. American Society for Microbiology, Washington, D.C.
17. Hoch, J. A. 1993. Regulation of the phosphorelay and the initiation of sporulation in Bacillus subtilis. Annu. Rev. Microbiol. 47:441-465.
18. Ireton, K., S. Jin, A. D. Grossman, and A. L. Sonenshein. 1995. Krebs cycle function is required for activation of the Spo0A transcription factor in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 92:2845-2849.
19. Jin, S. 1995. Ph.D. thesis. Tufts University, Boston, Mass.
20. Jin, S., and A. L. Sonenshein. 1994. Identification of two distinct Bacillus subtilis citrate synthase genes. J. Bacteriol. 176:4669-4679.
21. E synthesis in Bacillus subtilis. J. Bacteriol. 171:5226-5228.
22. Kenney, T. J., and C. P. Moran, Jr. 1987. Organization and regulation of an operon that encodes a sporulation-essential sigma factor in Bacillus subtilis. J. Bacteriol. 169:3329-3339.
23. LaPorte, D. C., P. E. Thorsness, and D. E. Koshland, Jr. 1985. Compensatory phosphorylation of isocitrate dehydrogenase. J. Biol. Chem. 260:10563-10568.
24. LeDeaux, J. R., and A. D. Grossman. 1995. Isolation and charcaterization of kinC, a gene that encodes a sensor kinase homologous to the sporulation sensor kinases KinA and KinB in Bacillus subtilis. J. Bacteriol. 177:166-175.
25. Levin, P. A., and R. Losick. 1996. Transcription factor Spo0A switches the localization of the cell division protein FtsZ from a medial to a bipolar pattern in Bacillus subtilis. Genes Dev. 10:478-488.
26. Londoño-Vallejo, A., C. Frehel, and P. Stragier. 1997. spaIIQ, a forespore-expressed gene required for engulfment in Bacillus subtilis. Mol. Microbiol. 24:29-39.
27. Losick, R., and P. Stragier. 1992. Crisscross regulation of cell-typc-specific gene expression during development in B. subtilis. Nature (London) 355: 601-604.
28. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
29. Matsuno, K., T. Conway, A. Turinsky, T. Henkin, and A. L. Sonenshein. Unpublished data.
30. E, the first compartment-specific transcription factor of B. subtilis, is regulated by an anti-σ factor that is also a protein kinase. Cell 74:735-742.
31. Mueller, J. P., and A. L. Sonenshein. 1992. Role of the Bacillus subtilis gsiA gene in regulation of early sporulation gene expression. J. Bacteriol. 174: 4374-4383.
32. Mueller, J. P., G. Bukusoglu, and A. L. Sonenshein. 1992. Transcriptional regulation of Bacillus subtilis glucose starvation-inducible genes: control of gsiA by the ComP-ComA signal transduction system. J. Bacteriol. 174:4361-4373.
33. Nakano, M. M., and P. Zuber. 1991. The primary role of comA in the establishment of the competent state in Bacillus subtilis is to activate the expression srfA. J. Bacteriol. 173:7269-7274.
34. Nakano, M. M., M. A. Marahiel, and P. Zuber. 1988. Identification of a genetic locus required for biosynthesis of the lipopeptide antibiotic surfactin in Bacillus sublilis. J. Bacteriol. 170:5662-5668.
35. Perego, M., and J. A. Hoch. 1996. Cell-cell communication regulates the effects of protein aspartate phosphatases on the phosphorelay controlling development in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 93:1549-1553.
36. Perego, M., C. Hanstein, K. M. Welsh, T. Djavakhishvili, P. Glaser, and J. A. Hoch. 1994. Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis. Cell 79:1047-1055.
37. Pogliano, K., E. Harry, and R. Losick. 1995. Visualization of the subcellular location of sporulation proteins in Bacillus subtilis using immunofluorescence microscopy. Mol. Microbiol. 18:459-470.
38. Roggiani, M., and D. Dubnau. 1993. ComA, a phosphorylated response regulator protein of Bacillus subtilis, binds to the promoter region of srfA. J. Bacteriol. 175:3182-3187.
39. Rong, S., M. S. Rosenkrantz, and A. L. Sonenshein. 1986. Transcriptional control of the Bacillus subtilis spoIID gene. J. Bacteriol. 165:771-779.
40. Schaeffer, P., J. Millet, and J.-P. Aubert. 1965. Catabolic repression of bacterial sporulation. Proc. Natl. Acad. Sci. USA 54:704-711.
41. F, is autoregulated. J. Bacteriol. 176:4104-4110.
42. Solomon, J. M., R. Magnuson, A. Srivastava, and A. D. Grossman. 1995. Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis. Genes Dev. 9:547-558.
43. Sonenshein, A. L. 1989. Metabolic regulation of sporulation and other stationary-phase phenomena, p. 109-130. In I. Smith, R. A. Slepecky, and P. Setlow (ed.), Regulation of procaryotic development. American Society for Microbiology, Washington, D.C.
44. Stragier, P., and R. Losick. 1990. Cascades of sigma factors revisited. Mol. Microbiol. 4:1801-1806.
45. Stragier, P., C. Bonamy, and C. Karmazyn-Campelli. 1988. Processing of a sporulation sigma factor in Bacillus subtilis: how morphological structure could control gene expression. Cell 52:697-704.
46. Wang, X., and J. Lutkenhaus. 1993. The FtsZ protein of Bacillus subtilis is localized at the division site and has GTPase activity that is dependent upon FtsZ concentration. Mol. Microbiol. 9:435-442.
47. Yansura, D. G., and D. J. Henner. 1984. Use of Escherichia coli lac repressor and operator to control gene expression in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 81:439-443.
48. Yousten, A. A., and R. S. Hanson. 1972. Sporulation of tricarboxylic acid cycle mutants of Bacillus subtilis. J. Bacteriol. 109:886-894.