Effect of mycobacterium avium infection on the influx, accumulation, and efflux of KRM-1648 by human macrophages

Microbial Drug Resistance

Volumn 3, Issue 3, 1997, Pages 277-282

  Bermudez, Luiz E ^a   Inderlied, Clark B ^b  

^a Kuzell Institute for Arthritis and Infectious Diseases   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIFALAZIL; RIFAMYCIN S DERIVATIVE;

ARTICLE; CELLULAR DISTRIBUTION; DRUG ACCUMULATION; DRUG EXCRETION; DRUG TRANSPORT; HUMAN; HUMAN CELL; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTE; PRIORITY JOURNAL;

ANIMALIA; MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM TUBERCULOSIS;

EID: 0030871705     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.1997.3.277     Document Type: Article

References (12)

1. Amsterdam, D. 1991. In V. Lorian (ed.), Susceptibility testing of antimicrobial agents in liquid medium. Williams & Wilkins. Baltimore, MD, pp. 53-105.
2. Bermudez, L.E., C. Inderlied, and L.S. Young. 1991. Stimulation with cytokines enhances penetration of Azithromycin into human macrophages. Antimicrob. Agents Chemother. 12:2625-2629.
3. Bermudez, L.E., P. Kolonoski, L.S. Young, and C.B. Inderlied. 1994. Activities of the benzoxazinorifamycin KRM 1648 and ethambutol against Mycobacterium avium complex in vitro and in macrophages. Antimicrob. Agents Chemother. 38:1844-1848.
4. Bermudez, L.E., M. Wu, and L.S. Young. 1993. Activation with cytokines and infection with Mycobacterium avium complex influence the uptake of clarithromycin by human macrophages. In Program and abstracts of 33rd Intersc. Conf. Antimicrob Agents Chemother. American Society for Microbiology. New Orleans, LA, abstract no. 307, 17.
5. Bermudez, L.E., and L.S. Young. 1988. Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex. J. Immunol. 140:3006-3013.
6. Crowle, A., R. Dahl, E. Ross, and M.H. May. 1991. Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect. Immun. 59:1823-1827.
7. Gerding, D.A.N., L.S. Peterson, C.E. Hughes, D.M. Bamberger, and T.A. Larson. 1991. Extravascular antimicrobial distribution and the respective blood concentrations in humans. In V. Lorian (ed.), Antibiotics in laboratory medicine. Williams & Wilkins, Baltimore, MD, pp. 880-961.
8. Inderlied, C.B., L. Barbara-Burnham, M. Wu, L.S. Young, and L.E. Bermudez. 1994. Activity of benzoxazinorifamycin-KRM 1648 against Mycobacterium avium complex in the beige mouse. Antimicrob. Agents Chemother. 38:1838-1843.
9. Saito, H., H. Tomioka, K. Sato, M. Emori, T. Yamane, K. Yamashita, K. Hosoe, and T. Hidaka. 1991. In vitro antimycobacterial activities of newly synthesized benzoxazinorifamycins. Antimicrob. Agents Chemother. 353:542-547.
10. Tomioka, H., H. Saito, K. Fjuii, K. Sato, and T. Hidaka. 1993. In vitro antimycobacterial activity of benzoxazinorifamycin, KRM 1648, against Mycobacterium avium complex, determined by the radiometric method. Antimicrob. Agents Chemother. 37:67-70.
11. Tomioka, H., H. Saito, K. Sato, T. Yamane, K. Yamashita, H. Hosoe, K. Fujii, and T. Hidaka. 1992. Chemotherapeutic efficacy of a newly synthesized benzoxazinorifamycin, KRM 1648, against Mycobacterium avium complex induced in mice. Antimicrob. Agents Chemother. 36:387-393.
12. Sutcliffe, J., A. Tait-Kamradt, and L. Wondrack. 1996. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: A common resistance pattern mediated by an efflux system. Antimicrob. Agents Chemother. 40:1817-1824.