Induction and suppression of anti-antibodies to syngeneic T cell- binding antibodies in mice

Clinical and Experimental Immunology

Volumn 109, Issue 1, 1997, Pages 180-184

  Kremmer, E ^a   Mysliwietz, J ^a   Thierfelder, S ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Anti antibodies; MoAb; Syngeneic anti T cell; Transplantation

Indexed keywords

T LYMPHOCYTE ANTIBODY;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BINDING AFFINITY; GENE TECHNOLOGY; GRAFT REJECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN GRAFT; SPECIES DIFFERENCE; T LYMPHOCYTE RECEPTOR GENE;

EID: 0030871426     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.4321331.x     Document Type: Article

References (15)

1. LoBuglio AF, Wheeler RH, Tang J et al. Mouse/human chimeric monoclonal antibody in man: kinetics and immune response. Proc Natl Acad Sci USA 1989; 86:4220-4.
2. Isaacs JD, Watts RA, Hazleman BL et al. Humanised monoclonal antibody therapy for rheumatoid arthritis. Lancet 1992; 340:748-52.
3. Kremmer E, Mysliwietz J, Lederer R et al. Murine anti-mouse T cell monoclonal antibodies elicit anti-antibodies in mice: intra-species immunization model for estimating potential patient sensitization against humanized anti-T cell antibodies. Eur J Immunol 1993; 23:1017-22.
4. Brüggemann M, Winter G, Waldmann H et al. The immunogenicity of chimeric antibodies. J Exp Med 1989; 170:2153-7.
5. Takemori T, Tesch H, Reth M et al. The immune response against anti-idiotope antibodies. I. Induction of idiotope-bearing antibodies and analysis of the idiotope repertoire. Eur J Immunol 1982; 12:1040-6.
6. Mysliwietz J, Thierfelder S, Hoffmann-Fezer G et al. Antilymphocytic antibodies and bone marrow transplantation. XI. Evidence that reduced Thy-1 expression in Thy-1.1 mice prevents suppression of graft-vs.-host disease with anti-Thy-1 monoclonal antibodies. Transplantation 1990; 49:749-55.
7. Kremmer E, Thierfelder S, Kummer U et al. Neutralization of immunosuppression by antibodies against variable as well as constant regions of monoclonal anti-Thy-1 xenoantihodies and their ability to be suppressed by initial T cell depletion. Transplantation 1989; 47:641-6.
8. Hoffmann-Fezer G, Gall C, Zengerle U et al. Immunohistology and immunocytology of human T-cell chimerism and graft-vs.-host disease in SCID mice. Blood 1993; 81:3440-8.
9. Mysliwietz J, Thierfelder S, Mocikat R et al. Immunological approach to inhibit formation of anti-antibodies to allo- and xenogeneic anti-T cell immunoglobulin. Eur J Immunol 1994; 24:2323-8.
10. Thierfelder S, Mocikat R, Mysliwietz J et al. Immunosuppression by Fc region-mismatched anti-T cell antibody treatment. Eur J Immunol 1995; 25:2242-6.
11. Ono R, Sakaguchi K, Ferrone S. Modulation by antiidiotypic monoclonal antibodies of immune lysis, mediated by anti-HLA monoclonal antibodies. J Immunol 1989; 143:1921-9.
12. Perosa F, Tsujisaki M, Ferrone S. Syngeneic anti-idiotypic antisera to murine monoclonal antibodies to monomorphic and polymorphic determinants of HLA class I antigen. J Immunol 1987; 138:2202-7.
13. Schmitt H, Khazaelli MB, Rodenburg CM et al. Production of mouse monoclonal anti-idiotypic antibodies specific to epitopes of tumor-associated mucin TAG-12. Hybridoma 1994; 13:389-96.
14. Klaus GGB. Antigen-antibody complexes elicit anti-idiotypic antibodies to self-idiotopes. Nature 1978; 272:265-6.
15. Thierfelder S, Mysliwietz J, Hoffmann-Fezer CJ et al. Antilymphocytic antibodies and marrow transplantation. XIV. Antibody-induced suppression of graft-vs.-host disease in C3-decomplemented mice differentiates two T-cell-depletion pathways. Blood 1991; 77:2285-91.