A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of α chain, β chain, and antigenic peptide, with immunogenicity in vitro and reduced affinity for bacterial superantigens

European Journal of Immunology

Volumn 27, Issue 8, 1997, Pages 1933-1941

  Zhu, Xiaojie ^a   Bavari, Sina ^b   Ulrich, Robert ^b   Sadegh Nasseri, Scheherazade ^c   Ferrone, Soldano ^d   McHugh, Louise ^a   Mage, Michael ^a,e  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NEW YORK MEDICAL COLLEGE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Covalent peptide; HLA DR1; Single chain; Superantigen

Indexed keywords

BACTERIAL ANTIGEN; COMPLEMENTARY DNA; HLA DR1 ANTIGEN; STAPHYLOCOCCUS ENTEROTOXIN A; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BACTERIAL IMMUNITY; CARBOXY TERMINAL SEQUENCE; CELLULAR IMMUNITY; DNA TRANSFECTION; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGENS, BACTERIAL; BASE SEQUENCE; CELL LINE; DNA PRIMERS; DNA, COMPLEMENTARY; EPITOPES; HLA-DR1 ANTIGEN; HUMANS; MICE; MOLECULAR WEIGHT; POLYMERASE CHAIN REACTION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SOLUBILITY; SUPERANTIGENS; T-LYMPHOCYTES; TRANSFECTION;

EID: 0030871346     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830270817     Document Type: Article

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