Psychosexual and psychosocial development in adult women with congenital adrenal hyperplasia. Results of interviews with patients and mothers;Sexuelle und psychosoziale entwicklung yon frauen mit adrenogenitalem syndrom: Ergebnisse eines interviews erwachsener patientinnen und deren mutter

Monatsschrift fur Kinderheilkunde

Volumn 145, Issue 8, 1997, Pages 815-821

  Kuhnle, U ^a,c   Bullinger, M ^b   Heinzlmann, M ^a   Knorr, D ^a  

^a Universitats Kinderkiimk   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Adult women; Congenital adrenal hyperplasia; Psychosexual and psychosocial development; Quality of life

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; FEMALE; FERTILITY; HUMAN; MARRIAGE; PARENTAL BEHAVIOR; PSYCHOSEXUAL DEVELOPMENT; QUALITY OF LIFE; SOCIAL ADAPTATION; SOCIAL PSYCHOLOGY;

EID: 0030870472     PISSN: 00269298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001120050183     Document Type: Article

References (39)

1. Baker SW (1980) Psychosexual differentiation in the human. Biol Reprod 22: 61-71
2. Bullinger M, Poppel E (1988) Lebensqualität in der Medizin: Schlagwort oder Forschungsansatz. Dtsch Arztebl 85: 679-680
3. Dittmann RW, Kappes MH, Kappes ME, Borger D, Stegner H, Willig RH, Wallis H (1990) Congenital adrenal hyperplasia I: Gender-related behavior and attitudes in female patients and sisters. Psychoendocrinology 15: 401-420
4. Dittmann RW, Kappes MH, Kappes ME, Börger D, Meyer-Bahlburg HFL, Stegner H, Willig RH, Wallis H (1990) Congenital adrenal hyperplasia I: Gender-related behavior and attitudes in female salt-wasting and simple-virilizing patients. Psychoendocrinology 15: 421-434
5. Donaldson MDC, Thomas PH, Love JG, Murray GD, McNinch AW, Savage CL (1994) Presentation, acute illness, and learning difficulties in salt-wasting 21-hydroxylase deficiency. Arch Dis Child 70: 214-218
6. Dörner G, Poppe I, Stahl F, Kolzsch J, Uebelhack RU (1991) Gene and environment-dependent neuroendocrine aetiogenesis of homosexuality and transexualism. Exp Clin Endocrinol 98: 141-150
7. Ehrhardt A, Epstein R, Money J (1968) Fetal androgens and female gender identity in the early-treated adrenogenital syndrome. Johns Hopkins Med J 122: 160-167
8. Ehrhardt AA, Baker SW (1977) Males and females with congenital adrenal hyperplasia. A family study of intelligence and gender-related behaviour. In: Lee PA, Plotwick LP, Kowarski AA, Migeon CJ (eds) Congenital adrenal hyperplasia. University Park Press, Baltimore, pp 447-461
9. Ehrhardt AA, Meyer-Bahlfaurg HFL (1981) Effects of prenatal sex hormones on gender-related behaviour. Science 211: 1312-1318
10. Federman DD (1987) Psychosexual adjustment in congenital adrenal hyperplasia. N Engl J Med 316: 209-211
11. Gordon AH, Lee PA, Dulcan MK, Finegold DN (1986) Behavioral problems, social competency, and self perception among girls with congenital adrenal hyperplasia. Child Psychiatry Hum Dev 17: 129-138
12. Grumbach M, Conte FA (1992) The adrenal cortex. In: Wilson JD, Foster DW (eds) Williams Textbook of endocrinology.8th end. Saunders, Philadelphia, pp 853-951
13. Hecker WCh (1989) Lebensqualität nach operativen Eingriffen in der Kinderchirurgie. Klin Padiatr 20: 1559-1568
14. Helleday J, Bartfai A, Ritzen EM, Forsman M (1994) General intelligence and cognitive profile in women with congenital adrenal hyperplasia (CAH). Psychoneuroendocrinology 19: 343-356
15. Hochberg Z, Gardos M, Benderly A (1987) Psychosexual outcome of assigned females and males with 46, XX virilizing congenital adrenal hyperplasia. Eur J Pediatr 146: 497-499
16. Hurtig AL, Radhakrishnan, Reyes HM, Rosenthal IM (1983) Psychological evaluation of treated females with virilizing congenital adrenal hyperplasia. J Pediatr Surg 8: 887-893
17. Kamp van der HJ, Slijper FME, Brandenburg H, Munck de SMPF, Drop SLS, Molenaar JC (1992) Evaluation of young women with congenital adrenal hyperplasia: a pilot study. Horm Res 3: 45-49
18. Klingensmith GJ, Garcia SC, Jones HW, Migeon G, Blizzard RM (1977) Glucocorticoid treatment of girls with congenital adrenal hyperplasia: effects on height, sexual maturation and fertility. J Pediatr 90: 996-1004
19. Kuhnle U, Bullinger M, Schwarz H-P, Knorr D (1993) Partnership and sexuality in adult female patients with congenital adrenal hyperplasia. First results of a cross-sectional quality of life evaluation. J Steroid Biochem Mol Biol 45: 123-126
20. Kuhnle U, Bullinger M, Schwarz HP (1995) The quality of life in adult female patients with congenital adrenal hyperplasia: a comprehensive study of the impact of genital malformations and chronic disease on female patients life. Eur J Pediatr 154: 708-716
21. Kuhnle U (1996) Congenital adrenal hyperplasia due to 21-hydroxylase deficiency: an update. JAMA 12: 6-8
22. Mattheis M (1980) Die Frustrations-Aggressions-Hypothese bei Mädchen mit adrenogenitalem Syndrom (AGS). Z Kinder Jugendpsychiatr 8: 314-322
23. Meyer-Bahlburg HFL (1984) Psychoendocrine-research on sexual orientation: current status and future options. In: Vries CJ De, Bruin JPC De, Uyling HBM, Comer MA (eds) Sex differences in brain, progress research in brain. Elsevier, Amsterdam NewYork, 61: 375-398
24. Money J, Schwartz M (1977) Dating, romantic and nonromantic friendships, and sexuality in 17 early-treated adrenogenital females, aged 16-25. In: Lee PA, Plotnick LP, Kowarski AA (eds) Congenital adrenal hyperplasia. University Park Press, Baltimore
25. Money J, Schwartz M, Lewis V (1984) Adult erotosexual status and fetal hormonal masculinisation and demasculinization: 46XX congenital virilizing adrenal hyperplasia and 46XY androgen-insensitivity syndrome compared. Psyehoneuroendocrinology 9: 405-414
26. Money J, Lewis V (1966) IQ, genetics and accelerated growth: adrenogenital syndrome. Bull Johns Hopkins Hosp 118: 365-373
27. Mulaikal RM, Migeon CJ, Rock JA (1987) Fertility rates in female patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. N Engl J Med 316: 178-182
28. Muller M, Bidlingmaier F, Förster C, Knorr D (1982) Psychosexuelles Verhalten von Frauen mit adrenogenitalem Syndrom. Helv Paediatr Acta 37: 571-580
29. Muller M, Kraus-Orlitta U, Dirlich-Wilhelm H, Forster C (1983) Motorisches Geschlechtsrollenverhalten bei Mädchen mit adrenogenitalem Syndrom. Eine Beobachtungsstudie zur geschlechtstypischen Körperhaltung. Z Kinder Jugendpsychiatr 11: 100-115
30. Mass R, Baker S (1991) Androgen effects on cognition: congenital adrenal hyperplasia. Psychoendocrinology 16: 189-201
31. Nie H, Hull CH, Steinbrenner K (1985) The statistical package for the social sciences. SPSS. McGraw-Hili, New York
32. Prader A (1954) Der Genitalbefund beim Pseudohermaphroditimus femininus des kongenitalen, adrenogenitaien Syndroms. Morphologie, Häufigkeit, Entwicklung und Vererbung der verschiedenen Genitalformen. Helv Paediatr Acta 9: 231-242
33. Reinisch JM, Sanders SA (1984) Prenatal gonadal steroidal influences on gender-related behaviour. In: Vries CJ de, Bruin JPC de, Uyling HBM, Comer MA (eds) Sex differences in brain, progress research in brain. Elsevier, Amsterdam New York, 61: 407-416
34. Slijper FME (1984) Androgens and gender role behaviour in girls with congenital adrenal hyperplasia (CAM). In: Vries CJ de. Bruin JPC de, Uyling HBM, Comer MA (eds) Sex differences in brain, progress research in brain. Elsevier, Amsterdam New York 61: 417-422
35. Speiser PW, Dupont J, Zhu D, New MI (1992) Disease expression and molecular genotype in congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J Clin Invest 90: 584-595
36. Swaab DF, Fliers E (1985) A sexually dimorphic nucleus in the human brain. Science 228: 1112-1115
37. Testa MA, Simonson DC (1996) Assessment of quality-of-life outcomes. N Engl J Med 334: 835-840
38. Wenzel U, Schneider M, Zachmann M, Knorr-Murset G (1978) Intelligence of patients with congenital adrenal hyperplasia due to 21-hydroxylase-deficiency, their parents and unaffected siblings. Helv Paediatr Acta 13: 13-16
39. White PC, New MI (1992) Genetic basis of endocrine disease 2: Congenital adrenal hyperplasia due to a 21-hydroxylase deficiency. J Clin Endocrinol Metab 74: 6-11