Wegrakingen tijdens simultaan gebruik van terfenadine en itraconazol

Nederlands Tijdschrift voor Geneeskunde

Volumn 141, Issue 36, 1997, Pages 1752-1754

  De Wildt, S N ^a   Van Den Anker, J N ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; CYTOCHROME P450; DIAZEPAM; IMIPRAMINE; ITRACONAZOLE; LIDOCAINE; TERFENADINE;

DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; HUMAN; LETTER; SYNCOPE; TORSADE DES POINTES;

ANTI-ALLERGIC AGENTS; ANTIFUNGAL AGENTS; DRUG INTERACTIONS; HUMANS; ITRACONAZOLE; SYNCOPE; TERFENADINE;

EID: 0030870064     PISSN: 00282162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Thummel KE, O'Shea D, Paine MF, Shen DD, Kunze KL, Perkins JD, et al. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism. Clin Pharmacol Ther 1996;59:491-502.
2. Pohjola-Sintonen S, Viitasalo M, Toivonene L, Neuvonen P. Torsades de pointes after terfenadine-itraconazole interaction. BMJ 1993;306:186.
3. Rau SE, Bend JR, Arnold MO, Tran LT, Spence JD, Bailey DO. Grapefruit juice-terfenadine single-dose interaction: magnitude, mechanism, and relevance. Clin Pharmacol Ther 1997;61:401-9.
4. Spence JD. Drug interactions with grapefruit: whose responsibility is it to warn the public? Clin Pharmacol Ther 1997;61:395-400.