Behavioural and pharmacological characterisation of the canopy stretched attend posture test as a model of anxiety in mice and rats

Psychopharmacology

Volumn 133, Issue 1, 1997, Pages 29-38

  Grewal, Savraj S ^a,b   Shepherd, Jon K ^a,c   Bill, David J ^a   Fletcher, Allan ^a,d   Dourish, Colin T ^a,d  

^a PFIZER INC   (United States)

^b DALHOUSIE UNIVERSITY   (Canada)

^c UNIVERSITY OF HAWAII   (United States)

^d Cerebrus Limited   (United Kingdom)

Author keywords

8 OH DPAT; Anxiety; Buspirone; Canopy; Chlordiazepoxide; Diazepam; Ipsapirone; mCPP; Mouse; Rat; Risk assessment; Stretched attend posture

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CHLORDIAZEPOXIDE; DIAZEPAM; IPSAPIRONE;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; BODY POSTURE; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; DRUG EFFECT; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; SUBCUTANEOUS DRUG ADMINISTRATION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BEHAVIOR, ANIMAL; CHLORDIAZEPOXIDE; DIAZEPAM; DRUG EVALUATION, PRECLINICAL; MALE; MICE; POSTURE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030869604     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050367     Document Type: Article

References (28)

1. Barnett SA (1966) The rat: a study in behaviour. Aldine, Chicago
2. 3 anagonists and benzodiazepines: their comparative behavioural pharmacology. Wiley, Chichester, pp 59-105
3. Bickerdike MJ, Marsden CA, Dourish CT, Fletcher A (1994) The influence of 5-hydroxytryptamine re-uptake blockade on CCK receptor antagonist effects in the rat elevated zero-maze. Eur J Pharmacol 271:403-411
4. Bill DJ, Knight M, Forster EA, Fletcher A (1991) Direct evidence for an important species difference in the mechanisms of 8-OH-DPAT-induced hypothermia. Br J Pharmacol 103:1857-1864
5. Blanchard RJ, Blanchard DC, Hori K (1989) An ethoexperimental approach to the study of defense. In: Blanchard RJ, Brain PF, Blanchard DC, Parmigiani S (eds) Ethoexperimental approaches to the study of behaviour. Kluwer, Dordrecht, pp 114-136
6. Blanchard RJ, Blanchard DC, Weiss SM, Meyer S (1990) The effects of ethanol and diazepam on reactions to predatory odors. Pharmacol Biochem Behav 35:775-780
7. Blanchard DC, Blanchard RJ, Rodgers RJ (1991) Risk assessment and animal models of anxiety. In: Olivier B, Mos J, Slangen JL (eds) Animal models in psychopharmacology. Birkhäuser, Basel, pp 117-134
8. Blanchard RJ, Yudko EB, Rodgers RJ, Blanchard DC (1993) Defense system psychopharmacology: an ethological approach to the pharmacology of fear and anxiety. Behav Brain Res 58: 155-165
9. Cole JC, Rodgers RJ (1994a) An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro 16-6208) in the murine elevated plus-maze. Behav Pharmacol 4:573-580
10. Cole JC, Rodgers RJ (1994b) Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: comparison with haloperidol. Psychopharmacology 114:288-296
11. 1C agonist. In: Briley M, File SE (eds) New concepts in anxiety. Macmillan, Fulwell, pp 154-167
12. Dawson GR, Crawford SP, Collinson N, Iversen SD, Tricklebank MD (1995) Evidence that the anxiolytic-like effects of chlordiazepoxide on the elevated plus maze are confounded by increases in locomotor activity. Psychopharmacology 118: 316-323
13. 1A receptors. Ellis Horwood, Chichester, pp 261-277
14. Garbe CM, Kemble ED, Rawleigh JM (1993) Novel odours evoke risk assessment and suppress appetitive behaviours in mice. Aggress Behav 19:447-454
15. Grant EW, Mackintosh JH (1963) A comparison of the social postures of some common laboratory rodents. Behaviour 21:246-259
16. Kaesermann HP (1986) Stretched attend posture, a non-social form of ambivalence, is sensitive to a conflict-reducing drug action. Psychopharmacology 89:31-37
17. Kahn RS, Wetzler S (1991) m-Chlorophenylpiperazine as a probe of serotonin function. Biol Psychiatry 30: 1139-1166
18. Kemble ED (1994) Novel odours increase defensiveness and inhibit attack behaviour in mice. In: Cooper SJ, Hendrie CA (eds) Ethology and psychopharmacology. Wiley, Chichester, pp 191-204
19. Molewijk HE, Van der Poel, AM Olivier B (1995) The ambivalent behaviour "stretched approach posture" in the rat as a paradigm to characterise anxiolytic drugs. Psychopharmacology 121:81-90
20. Moser PC (1989) An evaluation of the elevated plus-maze test using the novel anxiolytic buspirone. Psychopharmacology 99:48-53
21. Pinel JPJ, Mana MJ (1989) Adaptive interactions of rats with dangerous inanimate objects: support for a cognitive theory of defensive behaviour. In: Blanchard RJ, Brain PF, Blanchard DC, Parmigiani S (eds) Ethoexperimental approaches to the study of behaviour. Kluwer Academic, Dordrecht, pp 137-150
22. Pollard GT, Howard JL (1988) Effects of chlordiazepoxide, pentobarbital, buspirone, chlorpromazine, and morphine in the stretched attend posture (SAP) test. Psychopharmacology 94:433-434
23. Rodgers RJ, Cole JC (1994) The elevated plus-maze: pharmacology, methodology and ethology. In: Cooper SJ, Hendrie CA (eds) Ethology and psychopharmacology. Wiley, Chichester, pp 9-44
24. Rodgers RJ, Cole JC, Cobain MR, Daly P, Doran PJ, Ellis JR, Wallis P (1992) Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze: profile comparisons with 8-OH-DPAT, CGS12066B, TEMPP and mCPP. Behav Pharmacol 3:621-634
25. Shepherd JK, Grewal SS, Fletcher A, Bill DJ, Dourish CT (1994) Behavioural and pharmacological characterisation of the elevated "zero-maze" as an animal model of anxiety. Psychopharmacology 116:56-64
26. 3 antagonists and benzodiazepines: their comparative behavioural pharmacology. Wiley, Chichester, pp 107-131
27. Treit D, Menard J, Royan C (1993) Anxiogenic stimuli in the elevated plus-maze test. Pharmacol Biochem Behav 44:463-469
28. Van der Poel AM (1979) A note on "stretched attention", a behavioural element indicative of an approach avoidance conflict in rats. Anim Behav 27:446-450