Critical role of VAL/GLY86 HLA-DRB dimorphism in the neonatal resistance or susceptibility to maternal hepatitis C virus infection

Pediatric Infectious Disease Journal

Volumn 16, Issue 10, 1997, Pages 1001-1002

  Martinetti, Miryam ^a   Pacati, Ilaria ^b   Daielli, Cristina ^a   Salvaneschi, Laura ^a   Maccabruni, Anna ^b,c  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Hepatitis C virus; HLA molecular polymorphism; Vertical transmission

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN;

ARTICLE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEPATITIS C; HLA TYPING; HOST RESISTANCE; HUMAN; INFECTION RESISTANCE; INFECTION RISK; PLACENTAL TRANSFER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VIRUS TRANSMISSION;

DISEASE TRANSMISSION, VERTICAL; FEMALE; GENE FREQUENCY; GLYCINE; HAPLOTYPES; HEPATITIS C; HLA-DR ANTIGENS; HUMANS; INFANT, NEWBORN; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; VALINE;

EID: 0030869266     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-199710000-00019     Document Type: Article

References (5)

1. Manzini P, Saracco G, Cerchier A, et al. Human immunodeficiency virus infection as a risk factor for mother-to-child hepatitis C virus transmission; persistence of anti-hepatitis C virus in children is associated with the mother's anti-hepatitis C virus immunoblotting pattern. Hepatology 1995; 21:328-32.
2. Zanetti AR, Tanzi E, Paccagnini S, et al. Mother-to-infant transmission of hepatitis C. Lancet 1995;345:289-91.
3. Zuccotti GV, Ribero ML, Giovannini M, et al. Effect of hepatitis C genotype on mother-to-infant transmission of virus. J Pediatr 1995;127:278-80.
4. 86 HLA-DR beta dimorphism in autoantigen presentation to human T cells. Proc Natl Acad Sci USA 1991;88: 7343-7.
5. Winchester R, Chen Y, Rose S, et al. Major histocompatibility complex class II DR alleles DRB1* 1501 and those encoding HLA-DR13 are preferentially associated with a diminution in maternally transmitted human immunodeficiency virus 1 infection in different ethnic groups: determination by an automated sequence-based typing method. Proc Natl Acad Sci USA 1995;92:12374-8.