Immunohistochemical and ultrastructural investigation of the human vestibular dark cell area: Roles of subepithelial capillaries and T lymphocyte-melanophage interaction in an immune surveillance system

Anatomical Record

Volumn 249, Issue 2, 1997, Pages 153-162

  Masuda, Masazumi ^a   Yamazaki, Kazuto ^a   Kanzaki, Jin ^a   Hosoda, Yasuhiro ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Capillary; Dark cell; Human inner ear; Immune surveillance; LCA; Melanocyte; Melanophage; T lymphocyte; UCHL 1; vWF

Indexed keywords

CD45 ANTIGEN; GLUTARALDEHYDE; VON WILLEBRAND FACTOR;

ARTICLE; CAPILLARY BASEMENT MEMBRANE; CELL ULTRASTRUCTURE; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; INNER EAR; MELANOSOME; MONONUCLEAR CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; SEMICIRCULAR CANAL; STROMA CELL; T LYMPHOCYTE SUBPOPULATION; TRANSMISSION ELECTRON MICROSCOPY; UTRICLE;

ADULT; AGED; ANTIGENS, CD45; CAPILLARIES; EAR NEOPLASMS; EPITHELIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC SURVEILLANCE; MACROPHAGES; MALE; MIDDLE AGED; NEURILEMMOMA; SEMICIRCULAR CANALS; T-LYMPHOCYTES; VESTIBULE; VON WILLEBRAND FACTOR;

EID: 0030869022     PISSN: 0003276X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0185(199710)249:2<153::AID-AR1>3.0.CO;2-Z     Document Type: Article

References (36)

1. Arnold, W., H.J. Altermatt, J.O. Gebbers, and J. Laissue 1984 Secretory immunoglobulin A in the human endolymphatic sac: An immunohistochemical study. Orl J. Otorhinolaryngol. Relat. Spec., 46:286-288.
2. Bennett, H.S., J.H. Luft, and J.C. Hampton 1959 Morphological classifications of vertebrate blood capillaries. Am. J. Physiol., 196:381-390.
3. Blann, A. 1993 von Willebrand factor and the endothelium in vascular disease. Br. J. Biomed. Sci., 50:125-134.
4. Boesen, A.M., and P. Hokland 1982 Ultrastructure of normal human blood T lymphocyte subsets isolated by cell sorting using monoclonal antibodies: A stereological analysis. Virchows Arch. [Cell Pathol.], 41:107-117.
5. + melanophages appear in human epidermis after ultraviolet radiation. J. Invest. Dermatol., 86:363-370.
6. Cotran, R.S. 1994 Inflammation and repair. In: Robbins' Pathologic Basis of Disease, 5th ed. Cotran, R.S., V. Kumar, and S.L. Robbins, eds. Saunders, Philadelphia, pp. 51-92.
7. Harris, J.P. 1983 Immunology of the inner ear: Response of the inner ear to antigen challenge. Otolaryngol. Head Neck Surg., 91:18-32.
8. Harris, J.P., and P.A. Sharp 1990 Inner ear autoantibodies in patients with rapidly progressive sensorineural hearing loss. Laryngoscope, 100:516-524.
9. Ito, S., and K. Jimbow 1983 Quantitative analysis of eumelanin and pheomelanin in hair and melanomas. J. Invest. Dermatol., 80:268-272.
10. Jimbow, K., O. Oikawa, S. Sugiyama, and T. Takeuchi 1979 Comparison of eumelanogenesis and pheomelanogenesis in retinal and follicular melanocytes: Role of vesiculo-globular bodies in melanosome differentiation. J. Invest. Dermatol., 73:278-284.
11. Kanzaki, J. 1994 Immune-mediated sensorineural hearing loss. Acta Otolaryngol. (Stockh) Suppl., 514:70-72.
12. Kanzaki, J., R. Shiobara, and S. Toya 1991 Classification of the extended middle cranial fossa approach. Acta Otolaryngol. (Stockh) Suppl., 487:6-16.
13. Kurtin, P.J., and G.S. Pinkus 1985 Leukocyte common antigen: A diagnostic discriminant between hematopoietic and nonhematopoietic neoplasms in paraffin sections using monoclonal antibodies: Correlation with immunologic studies and ultrastructural localization. Hum. Pathol., 16:353-365.
14. LaFerriere, K.A., I.K. Arenberg, J.E. Hawkins, Jr., and L.G. Johnsson 1974 Melanocytes of the vestibular labyrinth and their relationship to the microvasculature. Ann. Otol. Rhinol. Laryngol., 83:685-694.
15. Masuda, M., K. Yamazaki, J. Kanzaki, and Y. Hosoda 1994 Ultrastructure of melanocytes in the dark cell area of human vestibular organs: Functional implications of gap junction, isolated cilia, and annulate lamellae. Anat. Rec., 240:481-491.
16. Masuda, M., K. Yamazaki, J. Kanzaki, and Y. Hosoda 1995a Ultrastructural evidence of cell communication between epithelial dark cells and melanocytes in vestibular organs of the human inner ear. Anat. Rec., 242:267-277.
17. Masuda, M., K. Yamazaki, J. Kanzaki, and Y. Hosoda 1995b Melanocytes in the dark cell area of human vestibular organs. Acta Otolaryngol. (Stockh) Suppl., 519:152-157.
18. Masuda, M., K. Yamazaki, J. Kanzaki, and Y. Hosoda 1996 Ultrastructural recognition of gap junctions between melanocytes in human vestibular organs by tannic acid containing fixative preparation and freeze-fracture technique. Anat. Rec., 246:8-14.
19. Mazzoni, A. 1990 The vascular anatomy of the vestibular labyrinth in man. Acta Otolaryngol. (Stockh) Suppl., 472:1-83.
20. McCabe, B.F. 1979 Autoimmune sensorineural hearing loss. Ann. Otol. Rhinol. Laryngol., 88:585-589.
21. McGhee, J.R., J. Mestecky, C.O. Elson, and H. Kiyono 1989 Regulation of IgAsynthesis and immune response by T cells and interleukins. J. Clin. Immunol., 9:175-199.
22. Nakane, P., and G.B. Pierce 1966 Enzyme-labeled antibodies: Preparation and application for the localization of antigens. J. Histochem. Cytochem., 14:929-931.
23. Rask-Anderson, H., and J. Stahle 1980 Immunodefense of the inner ear? Lymphocyte-macrophage interaction in the endolymphatic sac. Acta Otolaryngol. (Stockh), 89:283-294.
24. Ratnam, K.V., W.P.D. Su, S.C. Ziesmer, and C.Y. Li 1992 Value of immunohistochemistry in the diagnosis of leukemia cutis: Study of 54 cases using paraffin-section markers. J. Cutan. Pathol., 19:193-200.
25. Renkin, E.M. 1979 Relation of capillary morphology to transport of fluid and large molecules: A review. Acta Physiol. Scand. Suppl., 463:81-91.
26. Smith, S.H., M.H. Brown, D. Rowe, R.E. Callard, and P.C.L. Beverley 1986 Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL-1. Immunology, 58:63-70.
27. Soliman, A.M. 1992 Immune-mediated inner ear disease. Am. J. Otol., 13:575-579.
28. Streuli, M., C. Morimoto, M. Schrieber, S.F. Schlossman, and H. Saito 1988 Characterization of CD45 and CD45R monoclonal antibodies using transfected mouse cell lines that express individual human leukocyte common antigens. J. Immunol., 141:3910-3914.
29. Terry, L.A., M.H. Brown, and P.C.L. Beverley 1988 The monoclonal antibody UCHL-1 recognizes a 180,000 MW component of the human leucocyte common antigen, CD45. Immunology., 64:331-336.
30. Tomiyama, S., and J.P. Harris 1989 Elevation of inner ear antibody levels following direct antigen challenge of the endolymphatic sac. Acta Otolaryngol. (Stockh), 107:202-209.
31. Tomiyama, S., Y. Gotoh, T. Ikezono, and T. Yagi 1992 Vestibular disorders following immune response of the endolymphatic sac in the guinea pig. Ann. Otol. Rhinol. Laryngol., 101:54-57.
32. Veldman, J.E. 1986 Cochlear and retrocochlear immune-mediated inner ear disorders: Pathogenetic mechanisms and diagnostic tools. Ann. Otol. Rhinol. Laryngol., 95:535-540.
33. Wackym, P.A., U. Friberg, F.H. Linthicum, Jr., D. Bagger-Sjöbäck, H.T. Bui, F. Hofman, and H. Rask-Andersen 1987 Human endolymphatic sac: Morphologic evidence of immunologic function. Ann. Otol. Rhinol. Laryngol., 96:276-281.
34. Wagner, D.D., and R. Bonfanti 1991 von Willebrand factor and the endothelium. Mayo Clin. Proc. 66:621-7.
35. Warnke, R.A., K.C. Gatter, B. Falini, P. Hildreth, R.E. Woolston, K. Pulford, J.L. Cordell, B. Cohen, C. De Wolf-Peeters, and D.Y. Mason 1983 Diagnosis of human lymphoma with monoclonal anti leukocyte antibodies. N. Eng. J. Med., 309:1275-1281.
36. Watanabe, Y., N. Tamaoki, S. Habu, Y. Tashiro, S. Akatsuka, and Y. Enomoto 1974 Fine structural study on human T- and B-lymphocytes (author's translation). Nippon Ketsueki Gakkai Zasshi 37:655-666.