-
1
-
-
0025891436
-
Sepsis, the sepsis syndrome, multiple organ failure: A plea for comparable definitions
-
Bone RC (1991) Sepsis, the sepsis syndrome, multiple organ failure: a plea for comparable definitions. Ann Intern Med 114:332-333
-
(1991)
Ann Intern Med
, vol.114
, pp. 332-333
-
-
Bone, R.C.1
-
2
-
-
0025710312
-
Increase in national hospital discharge survey rates for septicemia
-
Centers for Disease Control (1990) Increase in national hospital discharge survey rates for septicemia. Morbidity and Mortality Weekly Report 39:31-34
-
(1990)
Morbidity and Mortality Weekly Report
, vol.39
, pp. 31-34
-
-
-
3
-
-
0019906260
-
Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli
-
Ziegler EJ, Mc Cutchan JA, Fierer J, Glauser MP et al. (1982) Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N Engl J Med 307:1225-1230
-
(1982)
N Engl J Med
, vol.307
, pp. 1225-1230
-
-
Ziegler, E.J.1
Mc Cutchan, J.A.2
Fierer, J.3
Glauser, M.P.4
-
4
-
-
0026016470
-
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin
-
Ziegler EJ, Fisher CJ, Sprung CL et al. (1991) Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. N Engl J Med 324:429-436
-
(1991)
N Engl J Med
, vol.324
, pp. 429-436
-
-
Ziegler, E.J.1
Fisher, C.J.2
Sprung, C.L.3
-
5
-
-
0021184906
-
The effects of high dose corticosteroids in patients with septic shock
-
Sprung CL, Caralis PV, Martial EH et al. (1984) The effects of high dose corticosteroids in patients with septic shock. N Engl J Med 311:1137-1143
-
(1984)
N Engl J Med
, vol.311
, pp. 1137-1143
-
-
Sprung, C.L.1
Caralis, P.V.2
Martial, E.H.3
-
6
-
-
0021341554
-
The relationship between oxygen delivery and consumption during fluid resuscitation of hypovolemic and septic shock
-
Kaufman BS, Rackow EC, Falk JL (1984) The relationship between oxygen delivery and consumption during fluid resuscitation of hypovolemic and septic shock. Chest 85:336-340
-
(1984)
Chest
, vol.85
, pp. 336-340
-
-
Kaufman, B.S.1
Rackow, E.C.2
Falk, J.L.3
-
7
-
-
0023239471
-
Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis
-
Veterans Administration Systems Sepsis Cooperative Study Group (1987) Effect of high-dose glucocorticoid therapy on mortality in patients with clinical signs of systemic sepsis. N Engl J Med 317:659-665
-
(1987)
N Engl J Med
, vol.317
, pp. 659-665
-
-
-
8
-
-
0023893831
-
Detection of circulating tumor necrosis factor after endotoxin administration
-
Michie HR, Manogue KR, Spriggs DR, Revhaug A, O'Dwyer S, Denarello CA, Cerai A, Wolff SM, Wilmore DW (1988) Detection of circulating tumor necrosis factor after endotoxin administration. N Engl J Med 318:1481-1486
-
(1988)
N Engl J Med
, vol.318
, pp. 1481-1486
-
-
Michie, H.R.1
Manogue, K.R.2
Spriggs, D.R.3
Revhaug, A.4
O'Dwyer, S.5
Denarello, C.A.6
Cerai, A.7
Wolff, S.M.8
Wilmore, D.W.9
-
9
-
-
0023254462
-
Controversies in the use of passive immunotherapy for bacterial infections in the critically ill patient
-
Baumgartner JD, Glauser MP (1987) Controversies in the use of passive immunotherapy for bacterial infections in the critically ill patient. Rev Infect Dis 9:194-205
-
(1987)
Rev Infect Dis
, vol.9
, pp. 194-205
-
-
Baumgartner, J.D.1
Glauser, M.P.2
-
10
-
-
0017233228
-
Effects of IgM and IgG antibody in patients with bacteremia due to gramnegative bacilli
-
Zinner SH, Mc Cabe WR (1976) Effects of IgM and IgG antibody in patients with bacteremia due to gramnegative bacilli. J Infect Dis 133:37-45
-
(1976)
J Infect Dis
, vol.133
, pp. 37-45
-
-
Zinner, S.H.1
Mc Cabe, W.R.2
-
11
-
-
0021362669
-
Anti-lipopolysaccharide immunotherapy in management of septic shock of obstetrical and gynaecological origin
-
Lachman E, Pitsoe SB, Gaffin SL (1984) Anti-lipopolysaccharide immunotherapy in management of septic shock of obstetrical and gynaecological origin. Lancet 1:981-983
-
(1984)
Lancet
, vol.1
, pp. 981-983
-
-
Lachman, E.1
Pitsoe, S.B.2
Gaffin, S.L.3
-
12
-
-
0024850782
-
Preliminary study on treatment of septic shock patients with antilipopolysaccharide IgG from blood donors
-
Fomsgaard A, Back L, Fomsgaard JS, Engquist A (1989) Preliminary study on treatment of septic shock patients with antilipopolysaccharide IgG from blood donors. Scand J Infect Dis 21:697-708
-
(1989)
Scand J Infect Dis
, vol.21
, pp. 697-708
-
-
Fomsgaard, A.1
Back, L.2
Fomsgaard, J.S.3
Engquist, A.4
-
13
-
-
0026052634
-
Treatment of gram-negative septic shock with an immunoglobulin preparation: A prospective, randomized clinical trial
-
Schedel I, Dreikhaussen U. Neutwig B et al. (1991) Treatment of gram-negative septic shock with an immunoglobulin preparation: a prospective, randomized clinical trial. Crit Care Med 19:1104-1113
-
(1991)
Crit Care Med
, vol.19
, pp. 1104-1113
-
-
Schedel, I.1
Dreikhaussen, U.2
Neutwig, B.3
-
14
-
-
0021077999
-
Ineffectiveness of single-dose human antiserum to core glycolipid (Escherichia coli 15) for prophylaxis of bacteremic, gram-negative infection in patients with prolonsed neutropenia
-
Mc Cutchan JA, Wolf JL, Ziegler EJ, Brande AI (1988) Ineffectiveness of single-dose human antiserum to core glycolipid (Escherichia coli 15) for prophylaxis of bacteremic, gram-negative infection in patients with prolonsed neutropenia. Schw Mediz Woch 113 suppl: 40-45
-
(1988)
Schw Mediz Woch
, vol.113
, Issue.SUPPL.
, pp. 40-45
-
-
Mc Cutchan, J.A.1
Wolf, J.L.2
Ziegler, E.J.3
Brande, A.I.4
-
15
-
-
0021843019
-
Prevention of gram-negative shock and death in surgical patients by antibody to endotoxin core glycolipid
-
Baumgartner JD, Glauser PG, Mc Cutchan JA, et al. (1985) Prevention of gram-negative shock and death in surgical patients by antibody to endotoxin core glycolipid. Lancet 2:59-63
-
(1985)
Lancet
, vol.2
, pp. 59-63
-
-
Baumgartner, J.D.1
Glauser, P.G.2
Mc Cutchan, J.A.3
-
16
-
-
0026780301
-
Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: A prospective double blind study
-
J5 Study Group (1992) Treatment of severe infectious purpura in children with human plasma from donors immunized with Escherichia coli J5: a prospective double blind study. J Infect Dis 165:695-701
-
(1992)
J Infect Dis
, vol.165
, pp. 695-701
-
-
-
17
-
-
0023678354
-
Treatment of gram-negative septic shock with human IgG antibody to Escherichia coli J5: A prospective, double-blind, randomized trial
-
Calandra T, Glauser MP, Schellekens J, Verhoef J and the Switt-Dutch J5 Immunoglobulin Study Group (1988) Treatment of gram-negative septic shock with human IgG antibody to Escherichia coli J5: a prospective, double-blind, randomized trial. J Infect Dis 158:312-319
-
(1988)
J Infect Dis
, vol.158
, pp. 312-319
-
-
Calandra, T.1
Glauser, M.P.2
Schellekens, J.3
Verhoef, J.4
-
18
-
-
0026720270
-
Prophylactic intravenous administration of standard immune globulin as compared with core-lipopolysaccharidic immune globulin in patients at risk of postsurgical infection
-
The Intravenous Immunoglobulin Collaborative Study Group (1992) Prophylactic intravenous administration of standard immune globulin as compared with core-lipopolysaccharidic immune globulin in patients at risk of postsurgical infection. N Engl J Med 327:234-240
-
(1992)
N Engl J Med
, vol.327
, pp. 234-240
-
-
-
19
-
-
0000503018
-
Anti-endotoxin therapy
-
Sibbald WJ, Vincent JL (eds), Springer, Berlin, 1 vol, 406 p
-
Calandra T, Baumgartner JD (1995) Anti-endotoxin therapy. In: Critical trials for the treatment of sepsis. Update in Intensive Care and Emergency Medicine, 19. Sibbald WJ, Vincent JL (eds), Springer, Berlin, 1 vol, 406 p, pp 237-250
-
(1995)
Critical Trials for the Treatment of Sepsis. Update in Intensive Care and Emergency Medicine
, vol.19
, pp. 237-250
-
-
Calandra, T.1
Baumgartner, J.D.2
-
21
-
-
0027279973
-
Introduction of newtechnology into critical care practice: A history of HA-1A human monoclonal antibody against endotoxin
-
Luce JM (1993) Introduction of newtechnology into critical care practice: a history of HA-1A human monoclonal antibody against endotoxin. Crit Care Med 21:1233-1241
-
(1993)
Crit Care Med
, vol.21
, pp. 1233-1241
-
-
Luce, J.M.1
-
22
-
-
1642422420
-
Anti-endotoxin monoclonal antibodies
-
Siegel JP, Stein KE, Zoon KC (1992) Anti-endotoxin monoclonal antibodies (the FDA reply). N Engl J Med 327:890-891
-
(1992)
N Engl J Med
, vol.327
, pp. 890-891
-
-
Siegel, J.P.1
Stein, K.E.2
Zoon, K.C.3
-
23
-
-
0026582215
-
Anti-endotoxin monoclonal antibodies. A second look
-
Wenzsl RP (1992) Anti-endotoxin monoclonal antibodies. A second look. N Engl J Med 326:1151-1153
-
(1992)
N Engl J Med
, vol.326
, pp. 1151-1153
-
-
Wenzsl, R.P.1
-
24
-
-
85047697430
-
Antiendotoxin monoclonal antibodies for gram-negative sepsis: Guidelines from the Infectious Disease Society of America
-
Wenzel RP, Andriole T, Bartlett JG (1992) Antiendotoxin monoclonal antibodies for gram-negative sepsis: guidelines from the Infectious Disease Society of America. Clin Infect Dis 14:973-976
-
(1992)
Clin Infect Dis
, vol.14
, pp. 973-976
-
-
Wenzel, R.P.1
Andriole, T.2
Bartlett, J.G.3
-
26
-
-
0028557981
-
Treatment of septic shock with human monoclonal antibody HA-1A: A randomized, double-blind, placebo-controlled trial period
-
Mc Closkey RV, Straube RC, Sanders C, Smith CR and the CHESS Trial Study Group (1994) Treatment of septic shock with human monoclonal antibody HA-1A: a randomized, double-blind, placebo-controlled trial period. Ann Intern Med 121:1-5
-
(1994)
Ann Intern Med
, vol.121
, pp. 1-5
-
-
Mc Closkey, R.V.1
Straube, R.C.2
Sanders, C.3
Smith, C.R.4
-
27
-
-
0028081374
-
The French national registry of HA-1A (Centoxin) in septic shock. A cohort study of 600 patients
-
Anonyme (1994) The French national registry of HA-1A (Centoxin) in septic shock. A cohort study of 600 patients. Arch Intern Med 154:2484-2491
-
(1994)
Arch Intern Med
, vol.154
, pp. 2484-2491
-
-
-
28
-
-
0028129184
-
An evaluation of the hemodynamic effects of HA-1A human monoclonal antibody
-
Kett DH, Quartin AA, Sprung CL et al. (1994) An evaluation of the hemodynamic effects of HA-1A human monoclonal antibody. Crit Care Med 22:1227-1234
-
(1994)
Crit Care Med
, vol.22
, pp. 1227-1234
-
-
Kett, D.H.1
Quartin, A.A.2
Sprung, C.L.3
-
29
-
-
0025917510
-
A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis
-
Greenmam RL, Schein RMH, Martin MA et al. (1991) A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. JAMA 266:1097-1102
-
(1991)
JAMA
, vol.266
, pp. 1097-1102
-
-
Greenmam, R.L.1
Schein, R.M.H.2
Martin, M.A.3
-
30
-
-
0029043636
-
A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial
-
Bone RC, Balk RA, Fein AM, Perl TM, Wenzel RP, Reines HD et al. (1995) A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial. Crit Care Med 23:994-1006
-
(1995)
Crit Care Med
, vol.23
, pp. 994-1006
-
-
Bone, R.C.1
Balk, R.A.2
Fein, A.M.3
Perl, T.M.4
Wenzel, R.P.5
Reines, H.D.6
-
31
-
-
0002758938
-
Results of a second double-blind randomized controlled trial of antiendotoxin antibody E5 in gramnegative sepsis
-
Chicago
-
st ICAAC Chicago No 1170, p 294
-
(1991)
st ICAAC
, vol.1170
, pp. 294
-
-
Wenzel, R.1
Bone, R.C.2
Feui, A.3
-
32
-
-
0026736407
-
Observations using antiendotoxin antibody (E5) as adjuvant therapy in humans with suspected serious gram-negative sepsis
-
Greenberg RN, Wilson KM, Kunz AY, Wedel NI, Gorelick KJ (1992) Observations using antiendotoxin antibody (E5) as adjuvant therapy in humans with suspected serious gram-negative sepsis. Crit Care Med 20:730-735
-
(1992)
Crit Care Med
, vol.20
, pp. 730-735
-
-
Greenberg, R.N.1
Wilson, K.M.2
Kunz, A.Y.3
Wedel, N.I.4
Gorelick, K.J.5
-
33
-
-
6544274600
-
Novel approaches to the treatment of septic shock
-
Vincent JL (ed). Springer, Berlin, 1 Vol
-
Morrison DC, Silverstein R, Parmely MJ (1992) Novel approaches to the treatment of septic shock. In: Vincent JL (ed) Yearbook of Intensive Care and Emergency Medicine. Springer, Berlin, 1 Vol, pp 91-103
-
(1992)
Yearbook of Intensive Care and Emergency Medicine
, pp. 91-103
-
-
Morrison, D.C.1
Silverstein, R.2
Parmely, M.J.3
-
34
-
-
0022590062
-
Protection of mice against lethal endotoxemia by a lipid A precursor
-
Proctor RA, Will JA, Burhop KE, Raetz CRH (1986) Protection of mice against lethal endotoxemia by a lipid A precursor. Infect Immun 52:905-907
-
(1986)
Infect Immun
, vol.52
, pp. 905-907
-
-
Proctor, R.A.1
Will, J.A.2
Burhop, K.E.3
Raetz, C.R.H.4
-
35
-
-
0028214566
-
Endotoxin-binding and neutralizing properties of recombinant bactericidal/permeability-increasing protein and monoclonal antibodies HA-1A and E5
-
Marra MN, Thornton MB, Snable JL (1994) Endotoxin-binding and neutralizing properties of recombinant bactericidal/permeability-increasing protein and monoclonal antibodies HA-1A and E5. Crit Care Med 22:559-565
-
(1994)
Crit Care Med
, vol.22
, pp. 559-565
-
-
Marra, M.N.1
Thornton, M.B.2
Snable, J.L.3
-
36
-
-
0028324317
-
Human neutrophil bactericidal/ permeability-increasing protein reduces mortality rate from endotoxin challenge. A placebo-controlled study
-
Fisher CJ Jr, Marra MN, Palardy JE (1994) Human neutrophil bactericidal/ permeability-increasing protein reduces mortality rate from endotoxin challenge. A placebo-controlled study. Crit Care Med 22:553-558
-
(1994)
Crit Care Med
, vol.22
, pp. 553-558
-
-
Fisher Jr., C.J.1
Marra, M.N.2
Palardy, J.E.3
-
37
-
-
0025879415
-
Tumor necrosis factor (cachectin) and other cytokines in septic shock: A review of the literature
-
Dofferhoff ASM, Vellenga E, Limburg PC et al. (1991) Tumor necrosis factor (cachectin) and other cytokines in septic shock: a review of the literature. Neth J Med 39:45-62
-
(1991)
Neth J Med
, vol.39
, pp. 45-62
-
-
Dofferhoff, A.S.M.1
Vellenga, E.2
Limburg, P.C.3
-
38
-
-
0023912918
-
Cytokine appearance in human endotoxemia and primate bacteremia
-
Hesse DG, Tracey KJ, Fong Y, et al. (1988) Cytokine appearance in human endotoxemia and primate bacteremia. Surg Gynecol Obstet 166:147-153
-
(1988)
Surg Gynecol Obstet
, vol.166
, pp. 147-153
-
-
Hesse, D.G.1
Tracey, K.J.2
Fong, Y.3
-
40
-
-
0022485610
-
Cachectin and tumor necrosis factor as two sides of the same biological coin
-
Beutler B, Cerami A (1986) Cachectin and tumor necrosis factor as two sides of the same biological coin. Nature 320:584-588
-
(1986)
Nature
, vol.320
, pp. 584-588
-
-
Beutler, B.1
Cerami, A.2
-
41
-
-
0023118407
-
Cachectin: More than a tumor necrosis factor
-
Beutler B, Cerami A (1987) Cachectin: more than a tumor necrosis factor. N Engl J Med 316:379-385
-
(1987)
N Engl J Med
, vol.316
, pp. 379-385
-
-
Beutler, B.1
Cerami, A.2
-
42
-
-
0022411888
-
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin
-
Beutler B, Milsark IW, Cerami AC (1985) Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229:869-871
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.C.3
-
43
-
-
0023028369
-
Shock and tissue injury induced by recombinant human cachectin
-
Tracey KJ, Beutler B, Lowry SF et al. (1986) Shock and tissue injury induced by recombinant human cachectin. Science 234:470-473
-
(1986)
Science
, vol.234
, pp. 470-473
-
-
Tracey, K.J.1
Beutler, B.2
Lowry, S.F.3
-
44
-
-
0023884204
-
Participation of tumor necrosis factor in the mediation of gram-negative bacterial lipopolysaccharide-induced injury in rabbits
-
Mathison JC, Wolfson E, Ulevitch RJ (1988) Participation of tumor necrosis factor in the mediation of gram-negative bacterial lipopolysaccharide-induced injury in rabbits. J Clin Invest 81:1925-1937
-
(1988)
J Clin Invest
, vol.81
, pp. 1925-1937
-
-
Mathison, J.C.1
Wolfson, E.2
Ulevitch, R.J.3
-
45
-
-
0025333163
-
Prophylactic and therapeutic effects of a monoclonal antibody to tumor necrosis factor-α in experimental gram-negative shock
-
Silva AT, Bayston KF, Cohen J (1990) Prophylactic and therapeutic effects of a monoclonal antibody to tumor necrosis factor-α in experimental gram-negative shock. J Infect Dis 162:421-427
-
(1990)
J Infect Dis
, vol.162
, pp. 421-427
-
-
Silva, A.T.1
Bayston, K.F.2
Cohen, J.3
-
46
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia
-
Tracey KJ, Fong Y, Hesse DG et al. (1987) Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteremia. Nature 330:662-664
-
(1987)
Nature
, vol.330
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
-
47
-
-
0025193590
-
Survival of primates in LD 100 septic shock following therapy with antibody to tumor necrosis factor (TNFα)
-
Hinshaw LB, Tekamp-Olson P, Chang ACK et al. (1990) Survival of primates in LD 100 septic shock following therapy with antibody to tumor necrosis factor (TNFα). Circ Shock 30:279-292
-
(1990)
Circ Shock
, vol.30
, pp. 279-292
-
-
Hinshaw, L.B.1
Tekamp-Olson, P.2
Chang, A.C.K.3
-
48
-
-
0025336521
-
Efficacy of a monoclonal antibody directed against tumor necrosis factor in protecting neutropenic rats from lethal infection with Pseudomonas aeruginosa
-
Opal SM, Cross AS, Kelly NM et al. (1990) Efficacy of a monoclonal antibody directed against tumor necrosis factor in protecting neutropenic rats from lethal infection with Pseudomonas aeruginosa. J Infect Dis 161:1148-1152
-
(1990)
J Infect Dis
, vol.161
, pp. 1148-1152
-
-
Opal, S.M.1
Cross, A.S.2
Kelly, N.M.3
-
50
-
-
9844255840
-
Role of tumor necrosis factor (TNF) in experimental gram positive sepsis
-
Chicago
-
Wayne J, Silva A, Cohen J (1991) Role of tumor necrosis factor (TNF) in experimental gram positive sepsis. 31st ICAAC Chicago no 789
-
(1991)
31st ICAAC
, vol.789
-
-
Wayne, J.1
Silva, A.2
Cohen, J.3
-
51
-
-
0026079224
-
Divergent efficacy of antibody to tumor necrosis factor-α in intravascular and peritonitis models of septic shock
-
Bagdy GJ, Plessala KJ, Wilson LA, Thompson JJ, Nelson S (1991) Divergent efficacy of antibody to tumor necrosis factor-α in intravascular and peritonitis models of septic shock. J Infect Dis 163:83-88
-
(1991)
J Infect Dis
, vol.163
, pp. 83-88
-
-
Bagdy, G.J.1
Plessala, K.J.2
Wilson, L.A.3
Thompson, J.J.4
Nelson, S.5
-
52
-
-
9844223672
-
Failure of anti-TNF mAb in preventing death in peritonitis-induced gram-negative bacteremia in mice
-
Chicago
-
st ICAAC Chicago p 294 No 790
-
(1991)
st ICAAC
, vol.790
, pp. 294
-
-
Zanetti, G.1
Kohler, J.2
Heumann, D.3
-
54
-
-
0025942427
-
Efficacy of antilipopoly saccharide and anti-tumor necrosis factor monoclonal antibodies in a neutropenic model of Pseudomonas sepsis
-
Opal SM, Cross AS, Sadoff JC et al. (1991) Efficacy of antilipopoly saccharide and anti-tumor necrosis factor monoclonal antibodies in a neutropenic model of Pseudomonas sepsis. J Clin Invest 88:885-890
-
(1991)
J Clin Invest
, vol.88
, pp. 885-890
-
-
Opal, S.M.1
Cross, A.S.2
Sadoff, J.C.3
-
55
-
-
0025885113
-
Experimental elimination of tumor necrosis factor in low-dose endotoxin models has variable effects on survival
-
Franks AK, Kujawa KI, Yaffe LJ (1991) Experimental elimination of tumor necrosis factor in low-dose endotoxin models has variable effects on survival. Infect Immun 59:2609-2614
-
(1991)
Infect Immun
, vol.59
, pp. 2609-2614
-
-
Franks, A.K.1
Kujawa, K.I.2
Yaffe, L.J.3
-
56
-
-
0025362697
-
Monoclonal antibody to endotoxin core protects mice from Escherichia coli sepsis by a mechanisms independent of tumor necrosis factor and interleukine 6
-
Silva AT, Appelmelk BJ, Baurman WA, Bayston KF, Cohen J (1990) Monoclonal antibody to endotoxin core protects mice from Escherichia coli sepsis by a mechanisms independent of tumor necrosis factor and interleukine 6. J Infect Dis 162:454-459
-
(1990)
J Infect Dis
, vol.162
, pp. 454-459
-
-
Silva, A.T.1
Appelmelk, B.J.2
Baurman, W.A.3
Bayston, K.F.4
Cohen, J.5
-
57
-
-
0025298845
-
Monoclonal antibody to TNF in severe septic shock
-
Exley AR, Cohen J, Buurman W, Owen R, Lumley J, Hanson G, Aulakh JM, Bodmer M, Stephens S, Ridell A, Perry M (1990) Monoclonal antibody to TNF in severe septic shock. Lancet 2:1275-1277
-
(1990)
Lancet
, vol.2
, pp. 1275-1277
-
-
Exley, A.R.1
Cohen, J.2
Buurman, W.3
Owen, R.4
Lumley, J.5
Hanson, G.6
Aulakh, J.M.7
Bodmer, M.8
Stephens, S.9
Ridell, A.10
Perry, M.11
-
58
-
-
0027406403
-
Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis
-
Fisher CJ Jr, Opal SM, Dhainaut JF, Stephens S, Zimmerman JL, Nightingale P et al. (1994) Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. Crit Care Med 21:318-327
-
(1994)
Crit Care Med
, vol.21
, pp. 318-327
-
-
Fisher Jr., C.J.1
Opal, S.M.2
Dhainaut, J.F.3
Stephens, S.4
Zimmerman, J.L.5
Nightingale, P.6
-
59
-
-
9844241860
-
CDP 571, a CDR-grafted anti-human TNFα antibody in septic shock: Safety, pharmacokinetics and influence on cytokine levels
-
Dhainaut JF, Vincent JL, Richard C, Stephens S, Lejeune P, Martin C, Schlemmer B (1994) CDP 571, a CDR-grafted anti-human TNFα antibody in septic shock: safety, pharmacokinetics and influence on cytokine levels. Am J Resp Crit Care Med 149:A241
-
(1994)
Am J Resp Crit Care Med
, vol.149
-
-
Dhainaut, J.F.1
Vincent, J.L.2
Richard, C.3
Stephens, S.4
Lejeune, P.5
Martin, C.6
Schlemmer, B.7
-
61
-
-
0028421289
-
Repeated administration of a F(ab′)2 fragment of an antitumor necrosis factor a monoclonal antibody in patients with severe sepsis: Effects on the cardiovascular system and cytokine levels
-
Boekstegers P, Weidenhofer S, Zell R, Pilz G, Holler E, Ertel W et al. (1994) Repeated administration of a F(ab′)2 fragment of an antitumor necrosis factor a monoclonal antibody in patients with severe sepsis: effects on the cardiovascular system and cytokine levels. Shock 1; 237-245
-
(1994)
Shock
, vol.1
, pp. 237-245
-
-
Boekstegers, P.1
Weidenhofer, S.2
Zell, R.3
Pilz, G.4
Holler, E.5
Ertel, W.6
-
62
-
-
9344246862
-
Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195 F, in patients with sepsis and septic shock: A multicenter randomized, placebo-controlled, dose-ranging study
-
Reinhart K. Wiegand-Löhnert C, Grimminger F, Kaul M, Withington S, Treacher D et al. (1996) Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195 F, in patients with sepsis and septic shock: a multicenter randomized, placebo-controlled, dose-ranging study. Crit Care Med 24:733-742
-
(1996)
Crit Care Med
, vol.24
, pp. 733-742
-
-
Reinhart, K.1
Wiegand-Löhnert, C.2
Grimminger, F.3
Kaul, M.4
Withington, S.5
Treacher, D.6
-
63
-
-
0028957549
-
Efficacy and safety of monoclonal antibody to human tumor necrosis factor a in patients with sepsis syndrome: A randomized, controlled, double-blind, multicenter clinical trial
-
Abraham E, Wunderink R, Silverman H, Perl TM, Nasraway S, Levy H et al. (1995) Efficacy and safety of monoclonal antibody to human tumor necrosis factor a in patients with sepsis syndrome: a randomized, controlled, double-blind, multicenter clinical trial. JAMA 273:934-941
-
(1995)
JAMA
, vol.273
, pp. 934-941
-
-
Abraham, E.1
Wunderink, R.2
Silverman, H.3
Perl, T.M.4
Nasraway, S.5
Levy, H.6
-
64
-
-
0029835023
-
INTERSEPT: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-α in patients with sepsis
-
Cohen J, Carlet J for the INTERSEPT Study Group (1996) INTERSEPT: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-α in patients with sepsis. Crit Care Med 24:1431-1440
-
(1996)
Crit Care Med
, vol.24
, pp. 1431-1440
-
-
Cohen, J.1
Carlet, J.2
-
65
-
-
0006397809
-
Monoclonal antibody to human tumor necrosis factor (TNF mab): Multicenter efficacy and safety in patients with the sepsis syndrome
-
Wherry J, Wenzel R, Wunderink R, Silverman H, Perl T, Nasraway S et al. (1993) Monoclonal antibody to human tumor necrosis factor (TNF mab): multicenter efficacy and safety in patients with the sepsis syndrome, 33rd ICAAC p 246 no 696
-
(1993)
33rd ICAAC
, vol.696
, pp. 246
-
-
Wherry, J.1
Wenzel, R.2
Wunderink, R.3
Silverman, H.4
Perl, T.5
Nasraway, S.6
-
66
-
-
0029900294
-
Treatment of septic shock with tumor necrosis factor receptor:Fc fusion protein
-
Fisher CJ, Agosti JM, Opal M, Lowry SF, Balk RA, Sadoff JC et al. (1996) Treatment of septic shock with tumor necrosis factor receptor:Fc fusion protein. N Engl J Med 334:1997-1702
-
(1996)
N Engl J Med
, vol.334
, pp. 1997-11702
-
-
Fisher, C.J.1
Agosti, J.M.2
Opal, M.3
Lowry, S.F.4
Balk, R.A.5
Sadoff, J.C.6
-
67
-
-
0029192212
-
Tumor necrosis factor in sepsis: Mediator of multiple organ failure or essential part of host defense?
-
Van der Poll T, Lowry SF (1995) Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense? Shock 3:1-12
-
(1995)
Shock
, vol.3
, pp. 1-12
-
-
Van Der Poll, T.1
Lowry, S.F.2
-
68
-
-
0023617050
-
A urine inhibitor of interleukin-1 activity that blocks ligand binding
-
Seckinger P, Lowenthal JW, Williamson K, Dayer JM, Mc Donald HR (1987) A urine inhibitor of interleukin-1 activity that blocks ligand binding. J Immunol 139:1546-1549
-
(1987)
J Immunol
, vol.139
, pp. 1546-1549
-
-
Seckinger, P.1
Lowenthal, J.W.2
Williamson, K.3
Dayer, J.M.4
Mc Donald, H.R.5
-
69
-
-
0025904893
-
A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice
-
Alexander HR, Doherty GM, Buresh CM, Venzon DJ, Norton JA (1991) A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice. J Exp Med 173:1029-1032
-
(1991)
J Exp Med
, vol.173
, pp. 1029-1032
-
-
Alexander, H.R.1
Doherty, G.M.2
Buresh, C.M.3
Venzon, D.J.4
Norton, J.A.5
-
70
-
-
0025225333
-
Interleukin-1 receptor antagonist reduces mortality from endotoxin shock
-
Ohlsson K, Bjork P, Bergenfeldt M, Hageman R, Thompson RC (1990) Interleukin-1 receptor antagonist reduces mortality from endotoxin shock. Nature 348:550-552
-
(1990)
Nature
, vol.348
, pp. 550-552
-
-
Ohlsson, K.1
Bjork, P.2
Bergenfeldt, M.3
Hageman, R.4
Thompson, R.C.5
-
71
-
-
0028018567
-
Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: A randomized, open-label, placebo-controlled multicenter study
-
Fisher CJ Jr, Slotman GJ, Opal SM, Pribble JP, Bone RC, Emmanuel G et al. (1994) Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter study. Crit Care Med 22:12-21
-
(1994)
Crit Care Med
, vol.22
, pp. 12-21
-
-
Fisher Jr., C.J.1
Slotman, G.J.2
Opal, S.M.3
Pribble, J.P.4
Bone, R.C.5
Emmanuel, G.6
-
72
-
-
0028239555
-
Recombinant human interleukin-1 receptor antagonist in the treatment of patients with the sepsis syndrome. Results from a randomized, doubie-blind. placebo-controlled trial
-
Fisher JC Jr, Dhainaut JF, Opal SM, Pribble JP, Balk RA, Slotman TJ et al. (1994) Recombinant human interleukin-1 receptor antagonist in the treatment of patients with the sepsis syndrome. Results from a randomized, doubie-blind. placebo-controlled trial. JAMA 271:1836-1843
-
(1994)
JAMA
, vol.271
, pp. 1836-1843
-
-
Fisher Jr., J.C.1
Dhainaut, J.F.2
Opal, S.M.3
Pribble, J.P.4
Balk, R.A.5
Slotman, T.J.6
-
73
-
-
0025610846
-
Anti IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-α challenge in mice
-
Starnes HF, Pearce MK, Tewari A, Yim JH, Zou J, Abrams JS (1990) Anti IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-α challenge in mice. J Immunol 145:4185-4191
-
(1990)
J Immunol
, vol.145
, pp. 4185-4191
-
-
Starnes, H.F.1
Pearce, M.K.2
Tewari, A.3
Yim, J.H.4
Zou, J.5
Abrams, J.S.6
-
74
-
-
0026046064
-
Inhibition of macrophage-activating cytokines is beneficial in the acute septic response
-
Redmond HP, Chavin KD, Bromberg JS, Daly JM (1991) Inhibition of macrophage-activating cytokines is beneficial in the acute septic response. Ann Surg 214:502-509
-
(1991)
Ann Surg
, vol.214
, pp. 502-509
-
-
Redmond, H.P.1
Chavin, K.D.2
Bromberg, J.S.3
Daly, J.M.4
-
75
-
-
0027945044
-
Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: A randomized, double-blind, placebo-controlled, multicenter clinical trial
-
Dhainaut JF, Tenaillon A, le Tulzo Y et al. (1994) Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. Crit Care Med 22:1720-1728
-
(1994)
Crit Care Med
, vol.22
, pp. 1720-1728
-
-
Dhainaut, J.F.1
Tenaillon, A.2
Le Tulzo, Y.3
-
76
-
-
0029681864
-
Novel approaches to the treatment of sepsis: Lessons learned and future directions
-
Cross A (1996) Novel approaches to the treatment of sepsis: lessons learned and future directions. Shock 6:S71-S74
-
(1996)
Shock
, vol.6
-
-
Cross, A.1
|