Antisense properties of end-modified oligonucleotides targeted to Ha-ras oncogene

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 4, 1997, Pages 361-368

  Saison Behmoaras, Tula E ^a   Duroux, Isabelle ^a   Thuong, Nguyen T ^b   Asseline, Ulysse ^b   Hélène, Claude ^a  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE; ANTISENSE OLIGONUCLEOTIDE; INTERCALATING AGENT; LAURYL ALCOHOL; RIBONUCLEASE H;

ARTICLE; BREAST CELL; CELL CULTURE; CELL PROLIFERATION; CELL TRANSFORMATION; CODON; CONTROLLED STUDY; DNA MODIFICATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; ONCOGENE H RAS; POINT MUTATION; PRIORITY JOURNAL; RNA CLEAVAGE;

EID: 0030867794     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.361     Document Type: Article

References (4)

1. ASSELINE, U., THUONG, N.T., and HÉLÈNE, C. (1997). Synthesis and properties of oligonucleotides covalently linked to intercalating agents. New J. Chem. 21, 5-17.
2. BROWN, D.A., KANG, S.H., GRYAZNOV, S.M., DE DIONISIO, L., HEIDENREICH, O., SULLIVAN, S., XU, X., and NERENBERG, M.I. (1994). Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding. J. Biol. Chem. 269, 26801-26805.
3. CHANG, E.H., MILLER, P.S., CUSHMAN, C., DEVADES, K., PIROLLO, K.F., TS'O, P.O.P., and YU, Z.P. (1991). Antisense inhibition of ras p21 expression that is sensitive to a point mutation. Biochemistry 30, 8283-8286.
4. YAKUBOV, L., KHALED, Z., ZHANG, L., TRUNEH, A., VLASSOV, V., and STEIN, C.A. (1993). Mode of interaction of oligodeoxynucleotides with recombinant sCD4. J. Biol. Chem. 268, 18818-18823.