Endothelial eicosanoid metabolism and signal transduction during exposure to oxygen radicals injury

Thrombosis Research

Volumn 87, Issue 4, 1997, Pages 363-375

  Weigel, Guenter ^c   Griesmacher, Andrea ^a,b   Toma, Cyril D ^c   Baecker, Christoph ^c   Heinzl, Hans ^a   Mueller, Mathias M ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b KAISER FRANZ JOSEF HOSPITAL   (Austria)

^c NONE

Author keywords

Eicosanoids; Endothelial cells; Oxygen radicals; Signal transduction

Indexed keywords

CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; ICOSANOID; OXYGEN RADICAL; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; PROSTACYCLIN;

ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

CELLS, CULTURED; EICOSANOIDS; ENDOTHELIUM, VASCULAR; FREE RADICALS; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 0030867478     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(97)00140-0     Document Type: Article

References (24)

1. BERRIDGE, M.J., and IRVINE, R.F. Inositol phosphates and cell signaling. Nature 341, 197-205, 1989.
2. 2(s); comparison of arachidonoyl-selective and -nonselective enzymes. FASEB J. 7, 339-348, 1993.
3. 2 from macrophages and reduce the calcium requirement for activity. Biochem Biophys Acta 1045, 261-270, 1990.
4. BELL, R.L., KENNERLY, D.A., STANFORD, N., and MAJERUS, P.W. Diglyceride lipase: a pathway for arachidonate release from human platelets. Proc Natl Acad Sci USA 76, 3238-3241, 1979.
5. 2 Synthesis by Human Endothelial Cells. Arteriosclerosis and Thrombosis 12, 512-518, 1992.
6. JAFFE, E.A., GRULICH, J., WEKSLER, B.B., HAMPEL, G. and WATANABE, K. Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells. J Biol Chem 262, 8557-8565, 1987.
7. GRIESMACHER, A., WEIGEL, G., DAVID, M., SCHIMKE, I. and MUELLER, M.M. Influence of oxygen radicals generating agents on eicosanoid metabolism of human endothelial cells. Thromb Res 65, 721-731, 1992.
8. HEMLER, M.E.H. and LANDS, W.E.M. Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis. J Biol Chem 255, 6253-6261, 1979.
9. POLGAR, P. and TAYLOR, L. Stimulation of prostaglandin synthesis by ascorbic acid via hydrogen peroxide formation. Prostaglandins 19, 693-700, 1980.
10. TAYLOR, L., MENCONI, M.J. and POLGAR, P. Participation of hydroperoxides and oxygen radicals in the control of prostaglandin synthesis. J Biol Chem 258, 6855-6858, 1983.
11. ELLIOTT, S.J., ESKIN, S.G. and SCHILLING, W.P. Effect of t-butyl-hydroxyperoxide on bradykinin-stimulated changes in cytosolic calcium in vascular endothelial cells. J Biol Chem 264, 3806-3810, 1989.
12. ELLIOTT, S.J. and SCHILLING, W.P. Carmustine augments the effects of tert-butyl-hydroxyperoxide on calcium signalling in cultured pulmonary artery endothelial cells. J Biol Chem 265, 103-107, 1990.
13. ELLIOTT, S.J., MESZAROS, J.G., and SCHILLING, W.P. Effect of oxidant stress on calcium signaling in vascular endothelial cells. Free Radical Biol & Med 13, 635-650, 1992.
14. BOYER, C.S., BANNENBERG, G.L., NEVE, E.P.A., RYRFELDT, A., MOLDEUS, P. Evidence for the activation of the signal-responsive phospholipase A2 by exogenous hydrogen peroxide. Biochem Pharmacol 50, 753-761, 1995.
15. STÄUBLE, B., BOSCOBOINIK, D., TASINATO, A., AZZI, A. Modulation of activator protein-1 (AP-1) transcription factor and protein kinase C by hydrogen peroxide and D-α-tocopherol in vascular smooth muscle cells. Eur J Biochem 226, 393-402, 1994.
16. WEIGEL, G., GRIESMACHER, A., and MUELLER, M.M. Regulation of eicosanoid release in human umbilical vein endothelial cells. Thromb Res 62, 685-695, 1991.
17. BRADFORD, M.A. Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-255, 1976.
18. SCHRAUFSTATTER, I.U., HINSHAW, D.B., HYSLOP, P.A., SPRAGG, R.G. and COCHRANE, C.G. Oxidant injury of cells: DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide. J Clin Invest 77, 1312-1320, 1986.
19. COBBOLD, P.H. and RINK, T.J. Fluorescence and bioluminescence measurement of cytoplasmatic free calcium. Biochem J 248, 313-328, 1987.
20. BERRIDGE, M.J., DAWSON, R.M.C., DOWNES, C.P., HELSOP, J.P. and IRVINE, R.F. Changes in the levels of inositol phosphates after agonist dependent hydrolysis of membrane phosphoinositides. Biochem J 212, 473-482, 1983.
21. OGUSHI, M., KUGIYAMA, K., FUKUNAGA, K., MUROHARA, T., SUGIYAMA, S., MIYAMOTO, E. and YASUE, H. Protein kinase C inhibitors prevent impairment of endothelium-dependent relaxation by oxidatively modified LDL. Arteriosclerosis Thrombosis 13, 1525-1532, 1993.
22. WINDISCHBAUER, A., GRIESMACHER, A., and MUELLER, M.M. In vitro effects of hypoxia and reoxygenation on human umbilical endothelial cells. Eur J Clin Chem Clin Biochem 32, 279-284, 1994.
23. HAZEN, S.L., FORD, D.A. and GROSS, R.W. Activation of a membrane associated phospholipase A2 during rabbit myocardial ischemia which is highly selective for plasmalogen substrate. J Biol Chem 266, 5629-5633, 1991.
24. 2+ for membrane binding but not for catalytic activity. Biochem Biophys Res Comm 184, 118-124, 1992.