The sequence-specific cleavage of RNA by artificial chemical ribonucleases

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 4, 1997, Pages 423-430

  Häner, Robert ^a   Hall, Jonathan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DOUBLE STRANDED RNA; IMIDAZOLE DERIVATIVE; LANTHANIDE; MACROCYCLIC COMPOUND; MESSENGER RNA; METAL COMPLEX; POLYAMINE; RIBONUCLEASE;

CHEMICAL STRUCTURE; DRUG SAFETY; DRUG SPECIFICITY; DRUG STABILITY; DRUG SYNTHESIS; PRIORITY JOURNAL; REVIEW; RNA CLEAVAGE; RNA SEQUENCE; RNA STRUCTURE;

EID: 0030867331     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.423     Document Type: Review

References (6)

1. AGRAWAL, S. (1996). Antisense oligonucleotides: Towards clinical trials. Trends Biotech. 14, 376-387.
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3. BAMANN, E. (1939). Ueber "phospsphatatische" Wirkung von Hydrogelen. Angew. Chemie 52, 186-188.
4. BAMANN, E., TRAPMANN, H., and FISCHLER, F. (1954). Verhalten und Spezifität von Cer und Lanthan als Phosphatase-Modelle gegenüber Nucleinsäuren und Mononnucleotiden. Biochem. Z. 326, 89-96.
5. BARBIER, B., and BRACK, A. (1988). Basic polypeptides accelerate the hydrolysis of ribonucleic acids. J. Am. Chem. Soc. 110, 6880-6882.
6. ZUCKERMANN, R.N., COREY, D.R., and SCHULTZ, P.G. (1988). Site-selective cleavage of RNA by a hybrid enzyme. J. Am. Chem. Soc. 110, 1614-1615.