Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: Synthesis and characterization of a series of O,2- propano-Δ8-tetrahydrocannbinol analogs

Journal of Medicinal Chemistry

Volumn 40, Issue 20, 1997, Pages 3312-3318

  Reggio, P H ^a   Wang, T ^a   Brown, A E ^a   Fleming, D N ^a   Seltzman, H H ^a   Griffin, G ^a   Pertwee, R G ^a   Compton, D R ^a   Abood, M E ^a   Martin, B R ^a  

^a KENNESAW STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID RECEPTOR; PSYCHOTROPIC AGENT; RADIOLIGAND; TETRAHYDROCANNABINOL DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGEN BOND; MALE; MOOD; MOUSE; MUSCLE CONTRACTION; NONHUMAN; RAT; RECEPTOR AFFINITY; SOLVATION; STRUCTURE ACTIVITY RELATION; VAS DEFERENS;

ANIMALS; ISOMERISM; MICE; MODELS, CHEMICAL; NOCICEPTORS; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROCANNABINOL;

EID: 0030866421     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970136g     Document Type: Article

References (33)