Antidiabetic actions of insulin sensitizer alone or in combination with α-glucosidase inhibitor in genetically obese-diabetic rats, Wistar fatty

Japanese Pharmacology and Therapeutics

Volumn 25, Issue 2, 1997, Pages 35-41

  Odaka, Hiroyuki ^a   Sano, Yoko ^a   Amano, Nobuyuki ^a   Ikeda, Hitoshi ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Glucosidase inhibitor; Diabetes; Glucose tolerance; Insulin sensitizer; Obese; Pioglitazone HCl; Troglitazone; Voglibose; Wistar fatty rat

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; GLUCOSE; PIOGLITAZONE; TRIACYLGLYCEROL; TROGLITAZONE; VOGLIBOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG SCREENING; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HYPERGLYCEMIA; HYPERTRIGLYCERIDEMIA; MALE; NONHUMAN; OBESITY; ORAL DRUG ADMINISTRATION; ORAL GLUCOSE TOLERANCE TEST; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0030863861     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Hayakawa T et al : Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats. Biochem Biophys Res Commun 223 : 439-444, 1996
2. Sugiyama Y et al : Effects of pioglitazone on glucose and lipid metabolism in Wistar fatty rats. Arzneim-Forsch/Drug Res 40 : 263-267, 1990
3. Sugiyama Y et al : Effects of pioglitazone on hepatic and peripheral insulin resistance in Wistar fatty rats. Arzneim-Forsch/Drug Res 40 : 436-440, 1990
4. y. J Nutr Sci Vitaminol 38 : 27-37, 1992
5. Hales CN, Randle PJ : Immunoassay of insulin with insulin antibody precipitate. Biochem J 88 : 224-228, 1963