Immunoreactive proinsulin detected by enzyme-linked immunosorbent assay

Biomedical Research

Volumn 18, Issue 5, 1997, Pages 389-393

  Emura, Masahiko ^a   Nakanome, Hiroyuki ^a   Ito, Akio ^a  

^a Yuku Medias Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; INSULIN; MONOCLONAL ANTIBODY; PROINSULIN;

ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HORMONE BLOOD LEVEL; HUMAN; IMMUNOREACTIVITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0030862491     PISSN: 03886107     EISSN: None     Source Type: Journal    
DOI: 10.2220/biomedres.18.389     Document Type: Article

References (8)

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2. CHEVENNE D., Ruiz J., LOHMANN L., LAUDAT A., LEBLANC H., GRAY I. P., PASSA P. and PORQUET D. (1994) Immunoradiometric assay of human intact proinsulin applied to patients with type 2 diabetes, impaired glucose tolerance, and hyperandrogenism. Clin. Chem. 40, 754-757
3. COHEN R. M., NAKABAYASHI T., BLIX P. M., RUE P. A., SHOELSON S. E., ROOT M. A., FRANK B. H., REVERS R. R. and RUBENSTEIN A. H. (1985) A radioimmunoassay for circulating human proinsulin. Diabetes 34, 84-91
4. DHAHIR F. J,. COOK D. B. and SELF C. H. (1992) Amplified enzyme-linked immunoassay of human proinsulin in serum (detection limit: 0.1 pmol/L). Clin. Chem. 38, 227-232
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6. KEMMLER W., PETERSEN J. D. and STEINER D. F. (1974) Studies on the conversion of proinsulin to insulin. J. Biol. Chem. 246, 6789-6791
7. KJEMS L. L., RØDER M. E., DINESEN B., HARTLING S. G., JØRGENSEN P. N. and BINDER C. (1993) Highly sensitive enzyme immunoassay of proinsulin immunoreactivity with use of two monoclonal antibodies. Clin. Chem. 39, 2149-2150
8. KOMJATI M., NOWOTNY P. and WALDHÄUSL W. (1987) Radioimmunologic determination of human C-peptide and proinsulin in plasma with anti-C-peptide serum after prepurification by high-performance liquid chromatography. Anal. Chem. 59, 2010-2012