Use of circular dichroism spectroscopy in determining the conformation of a monoclonal antibody prior to its incorporation in an immunoliposome

Journal of Pharmaceutical and Biomedical Analysis

Volumn 16, Issue 3, 1997, Pages 507-513

  Ng, Ka Yun ^a   Zhao, Limin ^a   Meyer, Jeffrey D ^a   Rittmann Grauer, Lana ^b   Manning, Mark C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b Hybritech Incorporated   (United States)

Author keywords

Antibody; Circular dichroism; Immunoliposome; Spectroscopy; Target sensitive; Target specific

Indexed keywords

ANTIBODY CONJUGATE; IMMUNOLIPOSOME; MONOCLONAL ANTIBODY;

ANTIBODY STRUCTURE; ARTICLE; BREAST CANCER; CIRCULAR DICHROISM; CONFORMATION; CONJUGATION; DERIVATIZATION; DRUG TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SPECTROSCOPY;

ANTIBODIES, MONOCLONAL; CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; DRUG RESISTANCE, NEOPLASM; LIPOSOMES; PHOSPHATIDYLETHANOLAMINES; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; TUMOR CELLS, CULTURED;

EID: 0030862481     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(97)00101-5     Document Type: Article

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