Alternative splicing of ClC-6 (a member of the ClC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific

Biochemical Journal

Volumn 325, Issue 1, 1997, Pages 269-276

  Eggermont, Jan ^a   Buyse, Gunnar ^a   Voets, Thomas ^a   Tytgat, Jan ^a   De Smedt, Humbert ^a   Droogmans, Guy ^a   Nilius, Bernd ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; CLCN6 PROTEIN, HUMAN; CLCN6 PROTEIN, MOUSE; MESSENGER RNA; COMPLEMENTARY DNA;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL LINE; CELL STRAIN KB; CHEMISTRY; FETUS; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; KIDNEY; LEUKEMIA CELL LINE; MALE; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; ANIMAL CELL; BINDING SITE; BRAIN CELL; CARBOXY TERMINAL SEQUENCE; CELL STRAIN K 562; CONTROLLED STUDY; EXON; GENE EXPRESSION; GENE SEQUENCE; HUMAN CELL; INTRON; KIDNEY CELL; NONHUMAN; OPEN READING FRAME; PANCREAS CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SKELETAL MUSCLE; TESTIS CELL; THYMUS; TISSUE DISTRIBUTION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CHLORIDE CHANNELS; FETUS; HELA CELLS; HUMANS; JURKAT CELLS; KB CELLS; KIDNEY; MALE; MICE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ALIGNMENT; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030861920     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3250269     Document Type: Article

References (31)

1. Jentsch, T. J., Gunther, W., Pusch, M. and Schwappach, B. (1995) J. Physiol. (London) 482.P, S19-S25
2. Brandt, S. and Jentsch, T. J. (1995) FEBS Lett. 377, 15-20
3. Middleton, R. E., Pheasant, D. J. and Miller, C. (1994) Biochemistry 33, 13189-13198
4. Kieferle, S., Fong, P. Y., Bens, M., Vandewalle, A. and Jentsch, T. J. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 6943-6947
5. Adachi, S., Uchida, S., Ito, H., Hata, M., Hiroe, M., Marumo, F. and Sasaki, S. (1994) J. Biol. Chem. 269, 17677-17683
6. Furukawa, T., Horikawa, S., Terai, T., Ogura, T., Katayama, Y. and Hiraoka, M. (1995) FEBS Lett. 375, 56-62
7. Malinowska, D. H., Kupert, E. Y., Bahinski, A., Sherry, A. M. and Cuppoletti, J. (1995) Am. J. Physiol. 268, C191-C200
8. Steinmeyer, K., Ortland, C. and Jentsch, T. J. (1991) Nature (London) 354, 301-304
9. Jentsch, T. J., Steinmeyer, K. and Schwarz, G. (1990) Nature (London) 348, 510-514
10. Thiemann, A., Grunder, S., Pusch, M. and Jentsch, T. J. (1992) Nature (London) 356, 57-60
11. Sakamoto, H., Kawasaki, M., Uchida, S., Sasaki, S. and Marumo, F. (1996) J. Biol. Chem. 271, 10210-10216
12. Steinmeyer, K., Schwappach, B., Bens, M., Vandewalle, A. and Jentsch, T. J. (1995) J. Biol. Chem. 270, 31172-31177
13. Pusch, M., Steinmeyer, K. and Jentsch, T. J. (1994) Biophys. J. 66, 149-152
14. Koch, M. C., Steinmeyer, K., Lorenz, C., Ricker, K., Wolf, F., Otto, M., Zoll, B., Lehmann, H. F., Grzeschik, K. H. and Jentsch, T. J. (1992) Science 257, 797-800
15. Lloyd, S. E., Pearce, S. H. S., Fisher, S. E., Steinmeyer, K., Schwappach, B., Scheinman, S. J., Harding, B., Bolino, A., Devoto, M., Goodyer, P. et al. (1996) Nature (London) 379, 445-449
16. Kawasaki, M., Suzuki, M., Uchida, S., Sasaki, S. and Marumo, F. (1995) Neuron 14, 1285-1291
17. Kawasaki, M., Uchida, S., Monkawa, T., Miyawaki, A., Mikoshiba, K., Marumo, F. and Sasaki, S. (1994) Neuron 12, 597-604
18. Uchida, S., Sasaki, S., Furukawa, T., Hiraoka, M., Imai, T., Hirata, Y. and Marumo, F. (1993) J. Biol. Chem. 268, 3821-3824
19. Buyse, G., Voets, T., Tytgat, J., De Greet, C., Droogmans, G., Nilius, B. and Eggermont, J. (1997) J. Biol. Chem. 272, 3615-3621
20. Chomczynski, P. and Sacchi, N. (1987) Anal. Biochem. 162, 156-159
21. Edgell, C.-J. S., McDonald, C. C. and Graham, J. B. (1983) Proc. Natl. Acad. Sci. U.S.A. 80, 3734-3737
22. De Greef, C., Sehrer, J., Viana, F., Van Acker, K., Eggermont, J., Mertens, L., Raeymaekers, L., Droogmans, G. and Nilius, B. (1995) Biochem. J. 307, 713-718
23. Claros, M. G. and von Heijne, G. (1994) Comput. Appl. Biosci. 10, 685-686
24. Lamond, A. I. (1993) BioEssays 15, 595-603
25. Lorenz, C., Meyer-Kleine, C., Steinmeyer, K., Koch, M. C. and Jentsch, T. J. (1994) Hum. Mol. Genet. 3, 941-946
26. Green, N. M. (1992) Ann. N. Y. Acad. Sci. 671, 104-112
27. Eggermont, J., Wuytack, F. and Casteels, R. (1991) Biochim. Biophys. Acta 1088, 448-451
28. Korczak, B., Zarain-Herzberg, A., Brandl, C. J., Ingles, C. J., Green, N. M. and MacLennan, D. H. (1988) J. Biol. Chem. 263, 4813-4819
29. Zarain-Herzberg, A., MacLennan, D. H. and Periasamy, M. (1990) J. Biol. Chem. 265, 4670-4677
30. Engelman, D. M., Steitz, T. A. and Goldman, A. (1986) Annu. Rev. Biophys. Biophys. Chem. 15, 321-353
31. Furakawa, T., Horikawa, S., Terai, T., Ogura, T., Katayama, Y. and Hiraoka, M. (1997) FEBS Lett. 403, 11