Gastric contractions, secretions and injury in cold restraint

Neurogastroenterology and Motility

Volumn 9, Issue 3, 1997, Pages 187-192

  Ephgrave, K S ^a   Cullen, J J ^a   Broadhurst, K ^a   Kleiman Wexler, R ^a   Shirazi, S S ^a   Schulze Delrieu, K ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Gastric acidity; Gastric motility; Gastric mucin; Gastric mucosal injury; Hypercontractility; Stress ulceration

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FORCE; HISTOLOGY; IMMOBILIZATION STRESS; MALE; MUCUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; STOMACH CONTENT; STOMACH INJURY; STOMACH MOTILITY; STOMACH MUCOSA; STOMACH MUSCLE; STOMACH PH; STOMACH SECRETION; STOMACH ULCER; STOMACH VOLUME; STRAIN GAUGE TRANSDUCER;

EID: 0030861918     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.1997.d01-42.x     Document Type: Article

References (22)

1. Brodie DA, Valitski LS. Production of gastric hemorrhage in rats by multiple stresses. Proc Soc Exp Biol Med 1963; 113:998-1001.
2. Garrick T, Leung FW, Buack S, Hirabayashi K, Guth PH. Gastric motility is stimulated but overall blood flow is unaffected during cold restraint in the rat. Gastroenterology 1986; 91: 141-8.
3. Silen W, Merhav A, Simson J. The pathophysiology of stress ulcer disease. World J Surg 1981; 5: 165-74.
4. Kitigawa H, Fujiwara M, Osumi Y. Effect of water-immersion stress on gastric secretion and mucosal blood flow in rats. Gastroenterology 1979; 77: 298-302.
5. Niida H, Takeuchi K, Ueshima K, Okabe S. Vagally mediated acid hypersecretion and lesion formation in anesthetized rat under hypothermie conditions. Dig Dis Sci 1991; 36: 441-8.
6. Wolf U, Schwille PO, Engelhardt W. Gastric secretions, mucosal erosion and porto-systemic gastrin gradients are induced by different degress of stress in the rat. Res Exp Med 1981; 179: 229-37.
7. Hayase M, Takeuchi K. Gastric acid secretion and lesion formation in rats under water-immersion stress. Dig Dis Sci 1986; 31: 166-71.
8. Nishiwaki H, Takeda F, Kitigawa H, Kohei H. Roles of gastric acid secretion and motility in gastric mucosal lesion formation induced by water-immersion stress in rats. Scand J Gastroenterol 1989; 24 (Suppl. 162): 11-14.
9. Watanabe K. Some pharmacologie factors involved in formation and prevention of stress ulcer in rats. Chem Pharmacol Bull 1966; 14: 101-7.
10. Yano S, Akahane M, Harada M. Role of gastric motility in the development of stress induced gastric lesions of rats. Jap J Pharmocol 1978; 28: 607-15.
11. Mersereau WA, Hinchey EJ. Hypothermia-induced gastric hypercontractility in the genesis of the restraint ulcer. Can J Surg 1981; 24 (6): 622-5.
12. Mersereau WA, Hinchey EJ. Relationship between the gastric myoelectric and mechanical activity in the genesis of ulcers in indomethacin-insulin-treated rats. Dig Dis Sci 1988; 33: 200-8.
13. Livingston E, Howard TJ, Garrick T, Passaro E, Guth PH. Strong gastric contractions cause mucosal ischemia. Am J Physiol 1991; 260 (Gastrointest Liver Physiol 23): G524-30.
14. Garrick T, Buack S, Bass P. Gastric motility is a major factor in cold restraint-induced lesion formation in rats. Am J Physiol 1986; 250 (Gastrointest Liver Physiol 13): G191-9.
15. Hall R L, Miller R J, Peatfield A C, Richardson P S, Williams I, Lampert I. A colorimetric assay for mucous glycoproteins using alcian blue. Biochem Soc Trans 1980, 8: 72.
16. Wallace JL, Whittle BJR. Role of mucus in the repair of gastric epithelial damage in the rat: inhibition of epithelial recovery by mucolytic agents. Gastroenterology 1986; 91: 603-11.
17. Cullen JJ, Ephgrave KS, Kleiman-Wexler R, Broadhurst K. Angiotensin-converting enzyme inhibition, kinins and stress ulceration. Curr Surg 1990; 47: 452-4.
18. Kleiman RL, Ephgrave KS, Broadhurst K. The effects of intragastric and intravenous glucose on the restraint model of stress ulcerations. Dig Dis Sci 1992; 37: 1860-5.
19. Senay EC, Levine RJ. Synergisms between cold restraint for rapid production of stress ulcers in rats. Proc Soc Exp Biol Med 1967; 124: 1221-3.
20. Grant R. Emotional hypothermia in rabbits. Am J Physiol 1950; 160: 285-90.
21. Antoon JW, Gregg RV. The influence of body temperature on the production of ulcers of restraint in the rat. Gastroenterology 1976; 70: 747-50.
22. Mersereau WA, Lough JO, Hinchey EJ. Factors in formation and prevention of bandlike gastric lesions in the rat. Dig Dis Sci 1988; 33: 1445-53.