Total synthesis of phenazinomycin and its enantiomer via high-pressure reaction

Tetrahedron Letters

Volumn 38, Issue 28, 1997, Pages 4993-4996

  Kinoshita, Yoshiharu ^a   Kitahara, Takeshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYL ALCOHOL; ANTIBIOTIC AGENT; CYCLOHEXANONE DERIVATIVE; DOXORUBICIN; LAVANDUCYANIN; PERMANGANATE POTASSIUM; PHENAZINE DERIVATIVE; SESQUITERPENE;

ALKYLATION; ANIMAL CELL; ANTIBIOTIC BIOSYNTHESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENANTIOMER; LEUKEMIA P 388; MOUSE; MYCELIUM; NONHUMAN; PRESSURE; STEREOCHEMISTRY; STREPTOMYCES;

ANIMALIA; STREPTOMYCES;

EID: 0030861433     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01068-X     Document Type: Article

References (18)

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15. The structures of geranyl derivative 12 and trans, trans-farnesyl derivative 13 are shown below. (equation presented)
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17. 3OD, 300 MHz δ = 0.78 (3H, s), 0.84 (3H, s), 1.28 (2H, m), 1.48 (2H, m), 1.57 (2H, m), 1.65 (1H, m), 1.90 (2H, m), 1.98 (2H, m), 2.00 (3H, s), 4.39 (1H, s), 4.66 (1H, s), 5.14 (1H, t, J = 5.2 Hz), 5.32 (2H, d, J = 5.2 Hz), 6.39 (1H, d, J = 8.4 Hz), 6.59 (1H, d, J = 8.4 Hz), 7.70 (1H, dd, J = 7.8, 7.8 Hz), 7.88 (1H, d, J = 7.8 Hz), 7.90 (1H, dd, J = 8.4, 8.4 Hz), 8.02 (1H, dd, J = 7.8, 7.8 Hz), 8.33 (1H, d, J = 7.8 Hz)
18. -1