Thrombopoietin: Basic biology and clinical promise

Leukemia

Volumn 11, Issue SUPPL. 3, 1997, Pages 426-427

  Kaushansky, Kenneth ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOPOIETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; ERYTHROPOIESIS; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE;

EID: 0030861262     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Kaushansky K et al. Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature, 1994; 369: 568.
2. Zeigler FC, de Sauvage F, Widmer HR, Keller GA, Donahue C, Schreiber RD, Malloy B, Hass P, Eaton D, Matthews W. In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells. Blood, 1994; 84: 4045.
3. Kaushansky K, Broudy VC, Lin N, Jorgensen M, McCarty J, Fox N, Zucker-Franklin D, Loften-Day C. Thrombopoietin, the Mpl-ligand, is essential for full megakaryocyte development. Proc Natl Acad Sci USA, 1995; 92: 3234.
4. McDonald TP. Thrombopoietin: Its biology, purification, and characterization. Exp Hematol, 1988; 16: 201.
5. Hill RJ, Levin J. Regulators of thrombopoiesis: Their biochemistry and physiology. Blood Cells, 1989; 15: 141.
6. Kaushansky K, Broudy VC, Grossmann A, Humes J, Lin N, Ren H-P, Bailey MC, Papayannopoulou T, Forstrom JW, Sprugel KH. Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy. J Clin Invest, 1995; 96: 1683.
7. Kobayashi M, Laver JH, Kato T, Miyazaki H, Ogawa M. Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood, 1995; 86: 2494.