Cytomegalovirus optic neuritis

Current Opinion in Ophthalmology

Volumn 8, Issue 3, 1997, Pages 55-58

  Mansour, Ahmad M ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; GANCICLOVIR;

BLINDNESS; CYTOMEGALOVIRUS INFECTION; OPTIC NERVE DISEASE; PAPILLITIS; PRIORITY JOURNAL; RETINITIS; REVIEW; VISUAL ACUITY; VISUAL FIELD;

ANTIVIRAL AGENTS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DIAGNOSIS, DIFFERENTIAL; EYE INFECTIONS, VIRAL; GANCICLOVIR; HUMANS; OPTIC NERVE; OPTIC NEURITIS; RECURRENCE; VISUAL ACUITY;

EID: 0030861132     PISSN: 10408738     EISSN: None     Source Type: Journal    
DOI: 10.1097/00055735-199706000-00010     Document Type: Review

References (31)

1. Wilhelmus KR, Font RL, Lehmann RP, Cernoch PC: Cytomegalovirus • keratitis in acquired immunodeficiency syndrome. Arch Ophthalmol 1996, 114:869-872. This is the first report of CMV infection of the cornea associated with AIDS.
2. Mansour AM, Li H: Frosted retinal periphlebitis in the acquired immunodeficiency syndrome. Ophthalmologica 1993, 207:182-186.
3. Mansour AM. Li H, Segal E: Picture resembling hemicentral retinal vein • occlusion in AIDS: is it related to CMV? Ophthalmologica 1996, 210:108-111. Three HIV-seropositive patients presented with inferior hemicentral retinal vein occlusion and developed CMV retinitis. The authors speculate either of the two mechanisms: 1) venous occlusion may predispose to CMV retinitis by stasis and ischemic loss of endothelium or 2) early CMV infection of the large retinal veins may present a scenario similar to hemicentral retinal vein occlusion.
4. Friedman AH: The retinal lesions of the acquired immune deficiency syndrome. Trans Am Ophthalmol Soc 1984, 82:447-491.
5. Fabricius E-M, Moller AA, Prantl F: Involvement of the afferent visual pathway in HIV infection: the optic nerve and optic radiation/visual cortex. Fortschr Ophthalmol 1991, 88:721-730.
6. Mansour AM, Li H: Cytomegalovirus optic neuritis: characteristics, •• therapy and survival. Ophthalmologica 1995, 209:260-266. Cytomegalovirus optic neuritis is a rapidly blinding disease, and antiviral therapy can stabilize the vision if started early. Serial monitoring ol visual fields is indicated to detect subclinical relapse. Patients with CMV optic neuritis have a survival similar to that of patients with CMV retinitis alone.
7. Neuwirth J, Gutman I, Hofeldt AJ, et al: Cytomegalovirus retinitis in a young homosexual male with acquired immunodeficiency. Ophthalmology 1982. 89:805-808.
8. Rosecan LR, Stahl-Bayliss CM, Kalman CM, Laskm OL: Antiviral therapy for Cytomegalovirus retinitis in AIDS with dihydroxy propoxymethyl guanine. Am J Ophthalmol 1986, 101:405-418.
9. Winward KE, Hamed LM, Glaser JS: The spectrum of optic nerve disease in human immunodeficiency virus infection. Am J Ophthalmol 1989, 107:373-380.
10. Palestine AG, Stevens G Jr, Lane HC, et al.: Treatment of Cytomegalovirus retinitis with dihydroxy propoxymethyl guanine. Am J Ophthalmol 1986, 101:95-101.
11. Mansour AM: Neuro-ophthalmic findings in acquired immunodeficiency syndrome. J Clin Neuro Ophthalmol 1990, 10:167-174.
12. Grossniklaus HE, Frank KE, Tomsak RL: Cytomegalovirus retinitis and optic neuritis in acquired immune deficiency syndrome: report of a case. Ophthalmology 1987, 94:1601-1604.
13. Repose JS, Hilborne LH, Cancilla PA, Foos RY: Concurrent herpes simplex and Cytomegalovirus retinitis and encephalitis in the acquired immune deficiency syndrome (AIDS). Ophthalmology 1984, 91:1669-1677.
14. Bylsma SS, Achim CL, Wiley CA, et al.: The predictive value of Cytomegalovirus retinitis for Cytomegalovirus encephalitis in acquired immunodeficiency syndrome. Arch Ophthalmol 1995, 113:89-95.
15. Robinson MR, Streeten BW, Hampton GR. et al.: Treatment of Cytomegalovirus optic neuritis with dihydroxy propoxymethyl guanine [letter]. Am J Ophthalmol 1986, 102:533-534.
16. Holland GN, Sidikaro Y, Kreiger AE. et al.: Treatment of Cytomegalovirus retinopathy with ganciclovir. Ophthalmology 1987, 94:815-823.
17. Gross JG, Sadun AA, Wiley CA, Freeman WR: Severe visual loss related to isolated peripapillary retinal and optic nerve head cytomegalovirus infection. Am J Ophthalmol 1989, 108:691-698.
18. D'Amico DJ, Skolnik PR, Kosloff BR, et al: Resolution of cytomegalovirus retinitis with zidovudine therapy [letter]. Arch Ophthalmol 1988, 106:1168-1169.
19. Smith JL, Byrne SF, Cambron CR: Syphiloma/gumma of the optic nerve and human immunodeficiency virus seropositivity. J Clin Neuro Ophthalmol 1990, 10:175-184.
20. Passo MS, Rosenbaum JT: Ocular syphilis in patients with human immunodeficiency virus infection. Am J Ophthalmol 1988, 106:1-6.
21. Carter JB, Hamill RJ, Matoba AY: Bilateral syphilitic optic neuritis in a patient with a positive test for HIV. Arch Ophthalmol 1987. 105:1485-1486.
22. Zambrano W, Perez GM, Smith JL: Acute syphilitic blindness in AIDS. J Clin Neuro Ophthalmol 1987, 7:1-4.
23. Golnik KC, Newman SA, Wispelway B: Cryptococcal optic neuropathy in the acquired immune deficiency syndrome. J Clin Neuro Ophthalmol 1991, 11:96-103.
24. Lipson BK, Freeman WR, Beniz J, et al.: Optic neuropathy associated with cryptococcal arachnoiditis in AIDS patients. Am J Ophthalmol 1989, 107:523-527.
25. Mansour AM: Bacterial optic disk mass and toxoplasmic-like encephalitis in an HIV seropositive subject. Graefes Arch Clin Exp Ophthalmol 1993, 231:668-671.
26. Zimmer C, Nieuwenhuis I, Daniserkis M, et al.: Sudden blindness in an AIDS patient. Simultaneous infection with cytomegalovirus and herpes simplex viruses and development of malignant non-Hodgkin lymphoma. Klin Monatsbl Augenheilkd 1991, 199:48-52.
27. Rostad SW, Olson K, McDougall J, et al.: Transsynaptic spread of varicella zoster virus through the visual system-a mechanism of viral dissemination in the central nervous system. Hum Pathol 1989, 20:174-179.
28. Ormerod LD, Rhodes RH, Gross SA, et al.: Ophthalmic manifestations of acquired immune deficiency syndrome-associated progressive multifocal leukoencephalopathy. Ophthalmology 1996, 103:899-906
29. Brack MJ, Cleland PG, Owen RI, et al.: Anterior ischemic optic neuropathy in the acquired immune deficiency syndrome. B M J 1987, 295:696-697.
30. Sadun AA, Pepose JS, Madigan MC, et al.: AIDS-related optic neuropathy-• histological, virological and ultrastructural study. Graefes Arch Clin Exp Ophthalmol 1995, 233:387-398. The authors present the first evidence of HIV infection of the optic nerve in autopsy eyes with AIDS, after ruling out optic disc damage from miscellaneous causes like CMV.
31. Jabs DA, Green WR, Fox R, et al.: Ocular manifestations of acquired immune deficiency syndrome. Ophthalmology 1989, 96:1092-1099.