Effects of different formulations of mitoxantrone (solutions, nanospheres, liposomes) on glaucoma surgery in rabbits

Ophthalmic Research

Volumn 29, Issue 4, 1997, Pages 218-226

  Tilleul, P ^a   Denis, P ^a   Maignen, F ^a   Elena P P ^b   Nordmann, J P ^a   Leverge, R ^a   Rostene, W ^a  

^a HÔPITAL LARIBOISIÈRE   (France)

^b Iris Pharma   (France)

Author keywords

Glaucoma surgery; Liposomes; Mitoxantrone; Nanospheres; Rabbits

Indexed keywords

LIPOSOME; MITOMYCIN C; MITOXANTRONE; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORNEA OPACITY; DRUG FORMULATION; FIBROBLAST; FILTERING OPERATION; GLAUCOMA; GLAUCOMA SURGERY; INTRAOCULAR PRESSURE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SCLEROTOMY; SUBCONJUNCTIVAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

EID: 0030860198     PISSN: 00303747     EISSN: 14230259     Source Type: Journal    
DOI: 10.1159/000268016     Document Type: Article

References (25)

1. Skuta GL, Parrish RK Jr.: Wound healing in glaucoma filtering surgery. Surv Ophthalmol 1987:32: 149-170.
2. McGuigan IJB, Quigley HA, Lutty G, Enger C, Young E: The effects of α-penicillamine and daunorubicin on conjunctival fibroblast proliferation and collagen synthesis. Invest Ophthalmol Vis Sci 1988:29:112-118.
3. Heuer DK, Parrish RK, Grcssel MG, Hodapp F., Palmberg PF. Anderson DR: 5-Fluorouracil and glaucoma filtering surgery. II. A pilot study. Ophthalmology 1984:91: 384-394.
4. Kitazawa Y, Kawase K, Matsushita H, Minobe M: Trabeculectomy with mitomycin. A comparative study with fluorouracil. Arch Ophthalmol 1991;109:1693-1698.
5. Fantes FE, Heuer DK, Parrish RK Jr., Sossi N, Gressel MG: Topical fluorouracil: Pharmacokinetics in normal rabbit eyes. Arch Ophthalmol 1985;103:953-955.
6. Praia JA Jr., Sealt SKL, Minckler DS, Baerveldt G, Lee PP, Heuer DK: Postoperative complications and short-term outcome after 5-fluorouraeil or mitomycin-C trabeculectomy. J Glaucoma 1995:4:25-31.
7. Xu Y, Yang GH, Gin WM, Chen KQ, Song XH: Effect of subconjunctival daunorubicin on glaucoma surgery' in rabbits. Ophthalmol Surg 1993;24:382-388.
8. Xu Y, Yang GH, Song XH, Chen KQ: Experimental study for the inhibitory effect of daunorubicin and doxorubicin in conjunctival fibroblast proliferation. Chin J Ophthalmol 1991;27:112-114.
9. Denis P, Tilleul P, Baudrimont M, Kaplan A, Rostène W, Saraux H: Utilisation expérimentale de liposomes vectorisant un antimétabolite mitoxantrone dans la chirurgie filtrante. J Fr Ophthalmol 1993:16: 14-20.
10. Maignen F, Tilleul P, Billardon C, Xu-Van Opstal W-Y, Pelaprat D, Elcna PP, Denis P, Rostène W: Antiproliferative activity of a liposomal delivery system of mitoxan-tronc on rabbit subconjunctival fibroblasts in an ex-vivo model. J Ocul Pharmacol Tlicr 1996; 12:289-298.
11. Schwendener R, Fiberg HH, Berger MR, Berger DP: Evaluation of incorporation characteristics of mitox-antrone into unilamellar liposomes and analysis of their pharmacokinetic properties, acute toxicity, and antitumor efficacy. Cancer Che-mother Pharmacol 1991:27:429-439.
12. Schwendencr R, Lambrecht U, Eh-ninger G: Cytostatic and pharmacokinetic properties of mitoxantrone incorporated into small and unilamellar liposomes. Invest New Drugs 1989:7:336.
13. Labhasetwar V, Mohan MS, Doric AK: A study on zeta potential and dielectric constant of liposomes. J Microencapsul 1994:11:663-666.
14. Rolland A, Gibassier D, Sado P, Le Verge R: Méthodologie de preparation de vecteurs nanoparticulaircs à base de polymères acryliques. J Pharm Belg 1986:41:83-93.
15. Khaw PT, Doyle JW, Sherwood MB, Grierson I, Schultz G, McGor-ray S: Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin-C. Arch Ophthalmol 1993:111:263-267.
16. Khaw PT, Doyle JW, Sherwood MB, Smith MF, McGorray S: Effects of intraopcrative 5-fluorouracil or mitomycin-C on glaucoma filtration surgery in the rabbit. Ophthalmology 1993:100:367-372.
17. New RRC: Liposomes: A Practical Approach. London. Oxford University Press. 1990.
18. Alvarado JA: The use of liposome-encapsulated 5-fluoroorotate for glaucoma surgery'. J. Animal studies. Trans Am Ophthalmol Soc 1989;87:489-514.
19. Lee DA, Leong KW, Panek WC, Eng CT, Glasgow BJ: The use of bioerodible polymers and 5 fluorouracil in glaucoma filtration surgery. Invest Ophthalmol Vis Sci 1988,29: 1692-1697.
20. Skuta GL, Assil K, Parrish RK, Fol-berg R, Weinreb RN: Filtering surgery in owl monkeys treated with 5-fluorouridinc 5-monophosphatc entrapped in multivesicular liposomes. Am J Ophthalmol 1987:103: 714-716.
21. Stern WH, Heath TD, Lewis GP: Clearance and localization of intra-vitrcal liposomes in aphakic vitrec-tomized eye. Invest Ophthalmol Vis Sci 1987;28:907-911.
22. Marchal-Heussler L, Fcssi H, Devis-saguet JP, Hoffman M, Maincent P: Colloidal drug delivery systems for the eye. A comparison of the efficacy of three different polymers: Polyiso-butylcyanoacrylate. polylactic-co-glvcolic acid, poly-cpsilon-caprolac-ton. STP Pharma 1992:2:98-104.
23. Sarraf D, Eezzuduemhoi RD, Cheng Q, Wilson MR, Lee DA: Aqueous and vitreous concentration of mitomycin-C by topical administration after glaucoma filtration surgery in rabbits. Ophthalmology 1993:100: 1574-1579.
24. Mietz H, Addicks K, Diestclhorst M, Krieglstein GK: Extraocular application of mitomycin-C in a rabbit model: Cytotoxic effects on the ciliary body and epithelium. Ophthalmic Surg 1994:25:240-244.
25. Bergstrom TJ, Wilkinson WS. Skuta GL, Watnick RL, Elner VM: The effects of subconjunctival mitomycin C on glaucoma filtration surgery in rabbits. Arch Ophthalmol 1991: 109:1725-1730.