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Volumn 121, Issue 8, 1997, Pages 1523-1530

Effects of β2-agonist- and dexamethasone-treatment on relaxation and regulation of β-adrenoceptors in human bronchi and lung tissue

Author keywords

adrenoceptor agonist; Aminophylline; Asthma; Corticosteroid; Desensitization; Dexamethasone; Down regulation; Human bronchi; Human lung parenchyma; Isoprenaline

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; AMINOPHYLLINE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR; DEXAMETHASONE; ISOPRENALINE; TERBUTALINE;

EID: 0030860087     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701289     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 0028839684 scopus 로고
    • Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3
    • ALVAREZ, R., SETTE, C., YANG, D., EGLEN, R.M., WILHELM, R., SHELTON, E.R. & CONTI, M. (1995). Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3. Mol. Pharmacol., 48, 616-622.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 616-622
    • Alvarez, R.1    Sette, C.2    Yang, D.3    Eglen, R.M.4    Wilhelm, R.5    Shelton, E.R.6    Conti, M.7
  • 4
    • 0013974439 scopus 로고
    • Potentiation by hydrocortisone of response to catecholamines in vascular smooth muscle
    • BESSE, J.C. & BASS, A.D. (1976). Potentiation by hydrocortisone of response to catecholamines in vascular smooth muscle. J. Pharmacol. Exp. Ther., 154, 224-238.
    • (1976) J. Pharmacol. Exp. Ther. , vol.154 , pp. 224-238
    • Besse, J.C.1    Bass, A.D.2
  • 5
    • 0026048227 scopus 로고
    • Beta-adrenergic receptors and m-cholinergic receptors in human lung. Findings following in vivo and in vitro exposure to the β-adrenergic receptor agonist, terbutaline
    • BÖHM, M., GENGENBACH, S., HAUCK, R.W., SUNDER-PLASSMANN, L. & ERDMANN, E. (1991). Beta-adrenergic receptors and m-cholinergic receptors in human lung. Findings following in vivo and in vitro exposure to the β-adrenergic receptor agonist, terbutaline. Chest, 100, 1246-1253.
    • (1991) Chest , vol.100 , pp. 1246-1253
    • Böhm, M.1    Gengenbach, S.2    Hauck, R.W.3    Sunder-Plassmann, L.4    Erdmann, E.5
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • BRADFORD, M.N. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem., 72, 248-254.
    • (1976) Analyt. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.N.1
  • 8
    • 0019211130 scopus 로고
    • Tachyphylaxis to beta-adrenoceptor agonists in human bronchial smooth muscle: Studies in vitro
    • DAVIS, C. & CONOLLY, M.E. (1980). Tachyphylaxis to beta-adrenoceptor agonists in human bronchial smooth muscle: studies in vitro. Br. J. Clin. Pharmacol., 10, 417-423.
    • (1980) Br. J. Clin. Pharmacol. , vol.10 , pp. 417-423
    • Davis, C.1    Conolly, M.E.2
  • 9
    • 0020698043 scopus 로고
    • In-vitro desensitisation of β-adrenergic receptors in human neutrophils. Attenuation by corticosteroids
    • DAVIS, A.O. & LEFKOWITZ, R.J. (1983). In-vitro desensitisation of β-adrenergic receptors in human neutrophils. Attenuation by corticosteroids. J. Clin. Invest., 71, 565-571.
    • (1983) J. Clin. Invest. , vol.71 , pp. 565-571
    • Davis, A.O.1    Lefkowitz, R.J.2
  • 10
    • 0019372882 scopus 로고
    • Adrenoceptors: Molecular nature and role in atopic diseases
    • DJURUP, R. (1981). Adrenoceptors: molecular nature and role in atopic diseases. Allergy, 36, 289-307.
    • (1981) Allergy , vol.36 , pp. 289-307
    • Djurup, R.1
  • 11
    • 0016700885 scopus 로고
    • Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness
    • ELLUL-MICALLEF, R. & FENECH, F.F. (1975). Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness. Lancet, 2, 1269-1271.
    • (1975) Lancet , vol.2 , pp. 1269-1271
    • Ellul-Micallef, R.1    Fenech, F.F.2
  • 13
    • 0019152811 scopus 로고
    • Dexamethasone increases beta adrenoceptor density in human astrocytoma cells
    • FOSTER, S.J. & HARDEN, T.K. (1980). Dexamethasone increases beta adrenoceptor density in human astrocytoma cells. Biochem. Pharmacol., 29, 2151-2153.
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 2151-2153
    • Foster, S.J.1    Harden, T.K.2
  • 14
    • 0018116620 scopus 로고
    • Decreased beta-adrenergic receptors on polymorphonuclear leukocytes after adrenergic therapy
    • GALANT, S.P., DURISETI, L., UNDERWOOD, S. & INSEL, P.A. (1978). Decreased beta-adrenergic receptors on polymorphonuclear leukocytes after adrenergic therapy. N. Engl. J. Med., 299, 933-936.
    • (1978) N. Engl. J. Med. , vol.299 , pp. 933-936
    • Galant, S.P.1    Duriseti, L.2    Underwood, S.3    Insel, P.A.4
  • 15
    • 0022632747 scopus 로고
    • Beta agonist-induced desensitization in pig bronchus
    • GOLDIE, R.G., SPINA, D. & PATERSON, J.W. (1986). Beta agonist-induced desensitization in pig bronchus. J. Pharmacol. Exp. Ther., 237, 275-282.
    • (1986) J. Pharmacol. Exp. Ther. , vol.237 , pp. 275-282
    • Goldie, R.G.1    Spina, D.2    Paterson, J.W.3
  • 16
    • 0025797080 scopus 로고
    • Prescribed fenoterol and death from asthma in New Zealand, 1981-7: A further case-control study
    • GRAINGER, J., WOODMAN, K., PEARCE, N., CRANE, J., BURGESS, C., KEANE, A. & BEASLEY, R. (1991). Prescribed fenoterol and death from asthma in New Zealand, 1981-7: a further case-control study. Thorax, 46, 105-111.
    • (1991) Thorax , vol.46 , pp. 105-111
    • Grainger, J.1    Woodman, K.2    Pearce, N.3    Crane, J.4    Burgess, C.5    Keane, A.6    Beasley, R.7
  • 17
    • 0024341172 scopus 로고
    • Agonist-induced destabilization of β-adrenergic receptor mRNA
    • HADCOCK, J.R., WANG, H. & MALBON, C.C. (1989). Agonist-induced destabilization of β-adrenergic receptor mRNA. J. Biol. Chem., 264, 19928-19933.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19928-19933
    • Hadcock, J.R.1    Wang, H.2    Malbon, C.C.3
  • 18
    • 0027480556 scopus 로고
    • 2-Adrenoceptor desensitization in cultured human airway smooth muscle
    • 2-Adrenoceptor desensitization in cultured human airway smooth muscle. Clin. Sci., 84, 151-157.
    • (1993) Clin. Sci. , vol.84 , pp. 151-157
    • Hall, I.P.1    Daykin, K.2    Widdop, S.3
  • 19
    • 0020026211 scopus 로고
    • Airway response to salbutamol: Effect of regular salbutamol inhalations in normal, atopic, and asthmatic subjects
    • HARVEY, J.E. & TATTERSFIELD, A.E. (1982). Airway response to salbutamol: effect of regular salbutamol inhalations in normal, atopic, and asthmatic subjects. Thorax, 37, 280-287.
    • (1982) Thorax , vol.37 , pp. 280-287
    • Harvey, J.E.1    Tattersfield, A.E.2
  • 22
    • 0017736361 scopus 로고
    • β-Adrenergic agonist resistance in normal human airways
    • HOLGATE, S.T., BALDWIN, C.L. & TATTERSFIELD, A.E. (1977). β-Adrenergic agonist resistance in normal human airways. Lancet, 2, 375-377.
    • (1977) Lancet , vol.2 , pp. 375-377
    • Holgate, S.T.1    Baldwin, C.L.2    Tattersfield, A.E.3
  • 23
    • 0014179073 scopus 로고
    • Effects of epinephrine on asthmatic children
    • INOUE, S. (1967). Effects of epinephrine on asthmatic children. J. Allergy, 40, 337-348.
    • (1967) J. Allergy , vol.40 , pp. 337-348
    • Inoue, S.1
  • 24
    • 0020534303 scopus 로고
    • Glucocorticoids increase GTP-dependent adenylate cyclase activity in cultured fibroblasts
    • JOHNSON, G.S. & JAWORSKI, C.J. (1983). Glucocorticoids increase GTP-dependent adenylate cyclase activity in cultured fibroblasts. Mol. Pharmacol., 23, 648-653.
    • (1983) Mol. Pharmacol. , vol.23 , pp. 648-653
    • Johnson, G.S.1    Jaworski, C.J.2
  • 25
    • 0017335162 scopus 로고
    • Lack of bronchial beta adrenoceptor resistance in asthmatics during long term treatment with terbutaline
    • LARSSON, S., SVEDMYR, N. & THIRINGER, G. (1977). Lack of bronchial beta adrenoceptor resistance in asthmatics during long term treatment with terbutaline. J. Allergy Clin. Immunol., 59, 93-100.
    • (1977) J. Allergy Clin. Immunol. , vol.59 , pp. 93-100
    • Larsson, S.1    Svedmyr, N.2    Thiringer, G.3
  • 27
    • 0023795259 scopus 로고
    • 2-adrenergic receptor gene are obligate for glucocorticoid regulation of receptor mRNA levels
    • 2-adrenergic receptor gene are obligate for glucocorticoid regulation of receptor mRNA levels. Biochem. Biophys. Res. Commun., 154, 676-681.
    • (1988) Biochem. Biophys. Res. Commun. , vol.154 , pp. 676-681
    • Malbon, C.G.1    Hadcock, J.R.2
  • 28
    • 0030075351 scopus 로고
    • Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B
    • MANNING, C.D., MCLAUGHLIN, M.M., LIVI, G.P., CIESLINSKI, L.B., TORPHY, T.J. & BARNETTE, M.S. (1995). Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B. J. Pharmacol. Exp. Ther., 276, 810-818.
    • (1995) J. Pharmacol. Exp. Ther. , vol.276 , pp. 810-818
    • Manning, C.D.1    Mclaughlin, M.M.2    Livi, G.P.3    Cieslinski, L.B.4    Torphy, T.J.5    Barnette, M.S.6
  • 29
    • 0018640908 scopus 로고
    • Effect of hydrocortisone on beta-adrenergic receptors in lung membranes
    • MANO, K., AKBARZADEH, A. & TOWNLEY, R.G. (1979). Effect of hydrocortisone on beta-adrenergic receptors in lung membranes. Life Sci., 25, 1925-1930.
    • (1979) Life Sci. , vol.25 , pp. 1925-1930
    • Mano, K.1    Akbarzadeh, A.2    Townley, R.G.3
  • 30
    • 0019140633 scopus 로고
    • Hydrocortisone and human lymphocytes: Increases in cyclic adenosine 3′:5′-monophosphate and potentiation of adenylate cyclase-activating agents
    • MARONE, G., LICHTENSTEIN, L.M. & PLAUT, M. (1980). Hydrocortisone and human lymphocytes: increases in cyclic adenosine 3′:5′-monophosphate and potentiation of adenylate cyclase-activating agents. J. Pharmacol. Exp. Ther., 215, 469-478.
    • (1980) J. Pharmacol. Exp. Ther. , vol.215 , pp. 469-478
    • Marone, G.1    Lichtenstein, L.M.2    Plaut, M.3
  • 31
    • 0023232124 scopus 로고
    • Studies in vivo and in vitro of terbutaline-induced β-adrenoceptor desensitization in healthy subjects
    • MARTINSSON, A., LARSSON, K. & HJEMDAHL, P. (1987). Studies in vivo and in vitro of terbutaline-induced β-adrenoceptor desensitization in healthy subjects. Clin. Sci., 72, 47-54.
    • (1987) Clin. Sci. , vol.72 , pp. 47-54
    • Martinsson, A.1    Larsson, K.2    Hjemdahl, P.3
  • 33
    • 0025248159 scopus 로고
    • Chronic isoproterenol administration causes altered beta-adrenoceptor-Gs-coupling in guinea pig lung
    • NERME, V., ABRAHAMSSON, T. & VAUQUELIN, G. (1990). Chronic isoproterenol administration causes altered beta-adrenoceptor-Gs-coupling in guinea pig lung. J. Pharmacol. Exp. Ther., 252, 1341-1346.
    • (1990) J. Pharmacol. Exp. Ther. , vol.252 , pp. 1341-1346
    • Nerme, V.1    Abrahamsson, T.2    Vauquelin, G.3
  • 34
    • 0026776880 scopus 로고
    • Desensitization of the isolated β2-adrenergic receptor by β-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanism
    • PITCHER, J., LOHSE, M.J., CODINA, J., CARON, M.G. & LEFKOWITZ, R.J. (1992). Desensitization of the isolated β2-adrenergic receptor by β-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanism. Biochemistry, 31, 3193-3197.
    • (1992) Biochemistry , vol.31 , pp. 3193-3197
    • Pitcher, J.1    Lohse, M.J.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 35
    • 0014851299 scopus 로고
    • Asthma induced by adrenergic aerosols
    • REISMAN, R.E. (1970). Asthma induced by adrenergic aerosols. J. Allergy, 46, 162-177.
    • (1970) J. Allergy , vol.46 , pp. 162-177
    • Reisman, R.E.1
  • 36
    • 0025788724 scopus 로고
    • Comparative rates of desensitization of β-adrenergic receptors by the β-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase
    • ROTH, N.S., CAMPBELL, P.T., CARON, M.G., LEFKOWITZ, R.J. & LOHSE, M.J. (1991). Comparative rates of desensitization of β-adrenergic receptors by the β-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase. Proc. Natl. Acad. Sci. U.S.A., 88, 6201-6204.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 6201-6204
    • Roth, N.S.1    Campbell, P.T.2    Caron, M.G.3    Lefkowitz, R.J.4    Lohse, M.J.5
  • 37
    • 84969001783 scopus 로고
    • The attractions of proteins for small molecules and ions
    • SCATCHARD, G. (1949). The attractions of proteins for small molecules and ions. Ann. New York Acad. Sci., 51, 660-672.
    • (1949) Ann. New York Acad. Sci. , vol.51 , pp. 660-672
    • Scatchard, G.1
  • 39
    • 0019832095 scopus 로고
    • Thyroid hormone modulation of agonist-beta-adrenergic receptor interactions in the rat heart
    • STILES, G.L. & LEFKOWITZ, R.J. (1981). Thyroid hormone modulation of agonist-beta-adrenergic receptor interactions in the rat heart. Life Sci., 28, 2529-2536.
    • (1981) Life Sci. , vol.28 , pp. 2529-2536
    • Stiles, G.L.1    Lefkowitz, R.J.2
  • 40
    • 0025067443 scopus 로고
    • Action of corticosteroids on beta-adrenergic receptors
    • SVEDMYR, N. (1990). Action of corticosteroids on beta-adrenergic receptors. Am. Rev. Respir. Dis., 141, S31-S38.
    • (1990) Am. Rev. Respir. Dis. , vol.141
    • Svedmyr, N.1
  • 42
    • 0026996701 scopus 로고
    • Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity
    • TORPHY, T.J., ZHOU, H.L. & CIESLINSKI, L.B. (1992). Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity. J. Pharmacol. Exp. Ther., 263, 1195-1205.
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 1195-1205
    • Torphy, T.J.1    Zhou, H.L.2    Cieslinski, L.B.3
  • 43
    • 0014468189 scopus 로고
    • Adverse effects of inhalation of excessive amounts of nebulized isoproterenol in status asthmaticus
    • VAN METRE, T. (1969). Adverse effects of inhalation of excessive amounts of nebulized isoproterenol in status asthmaticus. J. Allergy Clin. Immunol., 43, 101-113.
    • (1969) J. Allergy Clin. Immunol. , vol.43 , pp. 101-113
    • Van Metre, T.1
  • 44
    • 8544269514 scopus 로고    scopus 로고
    • Regulation of β-adrenoceptors from human bronchi and lung tissue under conditions of hypoxia
    • ZÖLLINGER, D., HARTH, M., SCHULZ, C., EMSLANDER, H.P., PRÄUER, H. & HAUCK, R.W. (1996). Regulation of β-adrenoceptors from human bronchi and lung tissue under conditions of hypoxia. Eur. Resp. J., 9, 426s.
    • (1996) Eur. Resp. J. , vol.9
    • Zöllinger, D.1    Harth, M.2    Schulz, C.3    Emslander, H.P.4    Präuer, H.5    Hauck, R.W.6


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