New synthesis of SASRIN(TM) resin

Tetrahedron Letters

Volumn 38, Issue 45, 1997, Pages 7849-7850

  Katritzky, Alan R ^a   Toader, Dorin ^a   Watson, Karen ^b   Kiely, John S ^b  

^a University of Florida ^*  (United States)

^b Trega Biosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXY 2 METHOXYBENZALDEHYDE; RESIN; UNCLASSIFIED DRUG;

ARTICLE; CELL TRANSFORMATION; CHEMICAL BINDING; CHEMICAL REACTION KINETICS; REACTION ANALYSIS; REDUCTION; SYNTHESIS;

EID: 0030859727     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0040-4039(97)10132-0     Document Type: Article

References (17)

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15. -1): 1680 (CHO).
16. -1): 3588 (OH). The OH loading of the resin was determined by linking Fmoc-β-alanine with DIC/DMAP and UV spectrophotometric (λ = 290 nm) quantitative determination of Fmoc release upon treatment with piperidine/DMF = 1/4 (v/v) and the adequate mass correction: 0.96 mmol/g.
17. Abbreviations: DMA: N,N-dimethylacetamide; NMM: N-methylmorpholine; DIC: diisopropylcarbodiimide; DMAP: N,N-dimethyl-4-aminopyridine.