Phorbol esters stimulate muscle glucose transport by a mechanism distinct from the insulin and hypoxia pathways

American Journal of Physiology - Endocrinology and Metabolism

Volumn 273, Issue 1 36-1, 1997, Pages

  Hansen, Polly A ^a   Corbett, John A ^b   Holloszy, John O ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

GLUT 4 translocation; Myristoylated alanine rich C kinase substrate protein; Protein kinase C

Indexed keywords

CALPHOSTIN C; DIACYLGLYCEROL; GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; PHORBOL ESTER; PHORBOL ESTER DERIVATIVE; PROTEIN KINASE C;

ANIMAL TISSUE; ARTICLE; CELL SURFACE; GLUCOSE TRANSPORT; HYPOXIA; MALE; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE;

EID: 0030858852     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.273.1.e28     Document Type: Article

References (37)

1. 3H-1 myocytes. Biochem. J. 295: 155-164, 1993.
2. Blackshear, P. J., D. McNeill Haupt, and D. J. Stumpo. Insulin activation of protein kinase C: a reassessment. J. Biol. Chem. 266: 10946-10952, 1991.
3. Bruns, R. F., F. D. Miller, R. L. Merriman, J. J. Howbert, W. F. Heath, E. Kobayashi, I. Takahashi, T. Tamaoki, and H. Nakano. Inhibition of protein kinase C by calphostin C is light-dependent. Biochem. Biophys. Res. Commun. 176: 288-293, 1991.
4. Cartee, G. D., A. G. Douen, T. Ramlal, A. Klip, and J. O. Holloszy. Stimulation of glucose transport in skeletal muscle by hypoxia. J. Appl. Physiol. 70: 1593-1600, 1991.
5. Cheatham, B., C. J. Vlahos, L. Cheatham, L. Wang, J. Blenis, and C. R. Kahn. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell. Biol. 14: 4902-4911, 1994.
6. Clark, A. E., and G. D. Holman. Exofacial photolabelling of the human erythrocyte glucose transporter with an azitrifluoroethylbenzoyl-substituted bismannose. Biochem. J. 269: 615-622, 1990.
7. Cleland, P. J. F., G. J. Appleby, S. Rattigan, and M. G. Clark. Exercise-induced translocation of protein kinase C and production of diacylglycerol and phosphatidic acid in rat skeletal muscle in vivo. Relationship to changes in glucose transport. J. Biol. Chem. 264: 17704-17711, 1989.
8. Cormont, M., T. Gremeaux, J.-F. Tanti, E. Van Obberghen, and Y. Le Marchand-Brustel. Polymyxin B inhibits insulin-induced glucose transporter and IGFII receptor translocation in isolated adipocytes. Eur. J. Biochem. 207: 185-193, 1992.
9. Farese, R. V., M. L. Standaert, T. Arnold, B. Yu, T. Ishizuka, J. Hoffman, M. Vila, and D. R. Cooper. The role of protein kinase C in insulin action. Cell. Signal. 4: 133-143, 1992.
10. Fujise, A., K. Mizuno, Y. Ueda, S. Osada, S. Hirai, A. Takayanagi, N. Shimizu, M. Owada, H. Nakajima, and S. Ohno. Specificity of the high affinity interaction of protein kinase C with a physiological substrate, myristoylated alanine-rich protein kinase C substrate. J. Biol. Chem. 269: 31642-31648, 1994.
11. Goodyear, L. J., F. Giorgino, T. Balon, G. Condorelli, and R. J. Smith. Effects of contractile activity on tyrosine phosphoproteins and PI 3-kinase activity in rat skeletal muscle. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E987-E995, 1995.
12. Guma, A., P. Munoz, M. Camps, X. Testar, M. Palacin, and A. Zorzano. Inhibitors such as staurosporine, H-7 or polymyxin B cannot be used in skeletal muscle to prove the role of protein kinase C on insulin action. Biosci. Rep. 12: 413-424, 1992.
13. Henriksen, E. J., K. J. Rodnick, and J. O. Holloszy. Activation of glucose transport in skeletal muscle by phospholipase C and phorbol ester. Evaluation of the regulatory roles of protein kinase C and calcium. J. Biol. Chem. 264: 21536-21543, 1989.
14. Henriksen, E. J., M. D. Sleeper, J. R. Zierath, and J. O. Holloszy. Polymyxin B inhibits stimulation of glucose transport in muscle by hypoxia or contractions. Am. J. Physiol. 256 (Endocrinol. Metab. 19): E662-E667, 1989.
15. Holman, G. D., I. J. Kozka, A. E. Clark, C. J. Flower, J. Saltis, A. D. Habberfield, I. A. Simpson, and S. W. Cushman. Cell surface labeling of glucose transporter isoform GLUT4 by bis-mannose photolabel. Correlation with stimulation of glucose transport in rat adipose cells by insulin and phorbol ester. J. Biol. Chem. 265: 18172-18179, 1990.
16. Ishizuka, T., D. R. Cooper, H. Hernandez, D. Buckley, M. Standaert, and R. V. Farese. Effects of insulin on diacylglycerol-protein kinase C signaling in rat diaphragm and soleus muscles and relationship to glucose transport. Diabetes 39: 181-189, 1990.
17. Karasik, A., P. L. Rothenberg, K. Yamada, M. F. White, and C. R. Kahn. Increased protein kinase C activity is linked to reduced insulin receptor autophosphorylation in liver of starved rats. J. Biol. Chem. 265: 10226-10231, 1990.
18. Kelly, K. L., and N. B. Ruderman. Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle. J. Biol. Chem. 268: 4391-4398, 1993.
19. Kiley, S. C., A. R. Olivier, P. C. Gordge, W. J. Ryves, F. J. Evans, D. K. Ways, and P. J. Parker. 12-Deoxyphorbol-13-O-phenylacetate-20-acetate is not protein kinase C-β isozyme-selective in vivo. Carcinogenesis 15: 319-324, 1994.
20. Kirsch, D., B. Obermaier, and H. U. Haring. Phorbolesters enhance basal D-glucose transport but inhibit insulin stimulation of D-glucose transport and insulin binding in isolated rat adipocytes. Biochem. Biophys. Res. Commun. 128: 824-832, 1985.
21. Klip, A., and T. Ramlal. Protein kinase C is not required for insulin stimulation of hexose uptake in muscle cells in culture. Biochem. J. 242: 131-136, 1987.
22. Kobayashi, E., H. Nakano, M. Morimoto, and T. Tamaoki. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159: 548-553, 1989.
23. Lund, S., G. D. Holman, O. Schmitz, and O. Pedersen. Glut4 content in the plasma membrane of rat skeletal muscle: comparative studies of the subcellular fractionation method and the exofacial photolabelling technique using ATP-BMPA. FEBS Lett. 330: 312-318, 1993.
24. Lund, S., G. D. Holman, O. Schmitz, and O. Pedersen. Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin. Proc. Natl. Acad. Sci. USA 92: 5817-5821, 1995.
25. Nakanishi, H., K. A. Brewer, and J. H. Exton. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268: 13-16, 1993.
26. Navé, B. T., P. R. Shepherd, and K. Siddle. Effect of phorbol esters on phosphatidylinositol 3-kinase activity in adipocytes (Abstract). Biochem. Soc. Trans. 23: 183S, 1995.
27. Nishizuka, Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9: 484-496, 1995.
28. O'Farrell, P. H. High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250: 4007-4021, 1975.
29. Okada, T., Y. Kawano, T. Sakakibara, O. Hazeki, and M. Ui. Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. J. Biol. Chem. 269: 3568-3573, 1994.
30. Ryves, W. J., A. T. Evans, A. R. Olivier, P. J. Parker, and F. J. Evans. Activation of the PKC-isotypes α, β1, γ, δ and ∈ by phorbol esters of different biological activities. FEBS Lett. 288: 5-9, 1991.
31. Saltis, J., A. D. Habberfield, J. J. Egan, C. Londos, I. A. Simpson, and S. W. Cushman. Role of protein kinase C in the regulation of glucose transport in the rat adipose cell. Translocation of glucose transporters without stimulation of glucose transport activity. J. Biol. Chem. 266: 261-267, 1991.
32. Smith, R. L., P. J. Roach, and J. C. Lawrence, Jr. Insulin resistance in denervated skeletal muscle. Inability of insulin to stimulate dephosphorylation of glycogen synthase in denervated rat epitrochlearis muscles. J. Biol. Chem. 263: 658-665, 1988.
33. 3H-1 myocytes. J. Biol. Chem. 263: 8696-8705, 1988.
34. Tanti, J. F., N. Rochet, T. Gremeaux, E. Van Obberghen, and Y. Le Marchand-Brustel. Insulin-stimulated glucose transport in muscle. Evidence for a protein-kinase-C-dependent component which is unaltered in insulin-resistant mice. Biochem. J. 258: 141-146, 1989.
35. Wilson, C. M., and S. W. Cushman. Insulin stimulation of glucose transport activity in rat skeletal muscle: increase in cell surface GLUT4 as assessed by photolabelling. Biochem. J. 299: 755-759, 1994.
36. Yeh, J. I., E. A. Gulve, L. Rameh, and M. J. Birnbaum. The effects of wortmannin in rat skeletal muscle. Dissociation of signaling pathways for insulin- and contraction-activated hexose transport. J. Biol. Chem. 270: 2107-2111, 1995.
37. Young, D. A., J. J. Uhl, G. D. Cartee, and J. O. Holloszy. Activation of glucose transport in muscle by prolonged exposure to insulin: effects of glucose and insulin concentration. J. Biol. Chem. 261: 16049-16053, 1986.