Control of insulin secretion and glucose homeostasis in exercising diabetic rats with intrasplenic or kidney subcapsular islet grafts

Cell Transplantation

Volumn 6, Issue 4, 1997, Pages 413-422

  Houwing, Harmina ^a   Hilbrands, Luchiena G ^a   Van Suylichem, Paul T R ^a   Bruggink, Jan E ^a   Steffens, Anton B ^a   Strubbe, Jan H ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Exercise; Islet transplantation; Kidney capsule; Portal insulin delivery; Reinnervation; Spleen

Indexed keywords

ADRENALIN; CATECHOLAMINE; GLUCOSE; INSULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; EXERCISE; GLUCOSE HOMEOSTASIS; INSULIN BLOOD LEVEL; INSULIN RELEASE; KIDNEY CAPSULE; KIDNEY GRAFT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0030858825     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0963-6897(97)00001-8     Document Type: Article

References (43)

1. Bani, D.; Cortesini, C.; Sacchi, T.B. Effects of portacaval anastomosis on pancreatic islets of the graft. Dig. Dis. Sci. 39:1048-1054; 1994.
2. Barron, P.; Humar, A.; Davies, J.; Radziuk, J. Insulin sensitivity and glucose tolerance following transposition of pancreatic venous drainage to the systemic circulation. Transplant. Proc. 26:487-489; 1994.
3. Benthem, L.; Van der Leest, J.; Steffens, A.B.; Zijlstra, W.G. Metabolic and hormonal responses to adrenoceptor antagonists in exercising rats. Metabolism 44:245-251; 1995.
4. Brown, J.; Muller, Y.; Clark, W.R.; Molnar, I.G.; Heininger, D. Importance of hepatic portal circulation for insulin action in streptozotocin-diabetic rats transplanted with fetal pancreases. J. Clin. Invest. 64:1688-1694; 1979.
5. Cardin, S.; Doiron, B.; Lavoie, J-M. Effect of prolonged exercise on insulin level in the portal and peripheral venous circulation in rats. Int. J. Sports Med. 12:187-189; 1991.
6. Eisenhofer, G.; Esler, M.D.; Goldstein, D.S.; Kopin, I.J. Neuronal uptake, metabolism, and release of tritium-labeled norepinephrine during assessment of its plasma kinetics. Am. J. Physiol. 261:E505-E515; 1991.
7. Falholt, K.; Cutfield, R.; Alejandro, R.; Vølund, Aa.; Heding, L.G.; Mintz, D.H. Influence of portal delivery of insulin on intracellular glucose and lipid metabolism. Metabolism 40:122-126; 1991.
8. Federlin, K.F. Islet transplantation. The connection of experiment and clinic exemplified by the transplantation of islets of Langerhans. Exp. Clin. Endocrinol. 101:334-345; 1993.
9. Feldman, S.D.; Hirshberg, G.E.; Dodi, G.; Raizman, M.E.; Scharp, D.W.; Ballinger, W.F.; Lacy, P.E. Intrasplenic islet isografts. Surgery 82:386; 1977.
10. Galbo, H. Hormonal and metabolic adaptation to exercise. Stuttgart, Germany: Thieme; 1983
11. Giacca, A.; Fisher, S.J.; Shi, Z.Q.; Gupta, R.; Lickley, H.L.A.; Vranic, M. Importance of peripheral insulin levels for insulin-induced suppression of glucose proauction in depancreatized dogs. J. Clin. Invest. 90: 1769-1777; 1992.
12. Górska, M., Górski, J. Effect of prolonged exercise on plasma insulin level in portal vein and abdominal aorta in rats. Endocrinol. Exp. 23:43-47; 1989.
13. Henquin, J.C.; Malvaux, P.; Lambert, A.E. Glucagon immunoassay using polyethylene glycol to precipitate antibody-bound hormone. Diabetologia 10:61-68; 1974.
14. Hoelzer, D.R.; Dalsky, O.P.; Schwanz, N.S.; Clutter, W.E; Shah, S.D.; Holloszy, J.O.; Cryer, P.E. Epinephrine is not critical to prevention of hypoglycemia during exercise in humans. Am. J. Physiol. 251:E104-110; 1986.
15. Houwing, H.; Benthem, L.; Van Suylichem, P.T.R.; Van der Leest, J.; Strubbe, J.H.; Steffens, A.B. Islet transplantation in diabetic rats normalizes basal and exercise-induced energy metabolism. Diabetologia 38:919-926; 1995.
16. Houwing, H., Fränkel, K.M.A.; Strubbe, J.H.; Van Suylichem, P.T.R.; Steffens, A.B. The role of the sympathoadrenal system in exercise-induced inhibition of insulin secretion: Effects of islet transplantation. Diabetes 44:565-571; 1995.
17. Houwing, H.; Van Asperen, R.M.; Van der Zee, E.A; Van Suylichem, P.T.R.; Oestreicher, A.B.; Steffens, A.B.; Strubbe, J.H. Noradrenergic and cholinergic reinnervation of islets grafts in diabetic rats. Cell Transplant. 5:21-30; 1996.
18. International islet transplant registry (Hering, B.J.; Schultz, A.O.; Geier, C.; Bretzel, R.G.; Federlin, K.): ITR newsletter no. 6. Giessen, Germany; 1995.
19. Järhult, J.; Holst, J. The role of adrenergic innervation to the pancreatic islets in the control of insulin release during exercise in man. Pflugers Arch. 383:41-45; 1979.
20. Kemp, C.B.; Knight, M.J.; Scharp, D.W.; Ballinger, W.F.; Lacy, P.E. Effect of transplantation site on results of pancreatic islet isografts in diabetic rats. Diabetologia 9:486-491; 1973.
21. Korsgren, O.; Andersson, A.; Jansson, L.; Sundler, F. Reinnervation of syngeneic mouse pancreatic islets transplanted into renal subcapsular space. Diabetes 41:130-135; 1992.
22. Korsgren, O.; Jansson, L.; Andersson, A.; Sundler, F. Reinnervation of transplanted pancreatic islets. A comparison among islets implanted into the kidney, spleen and liver. Transplantation 56:138-143; 1993.
23. Kruszynska, Y.T.; Home, P.D.; Alberti, K.G.M.M. Comparison of portal and peripheral insulin delivery on lipid metabolism in streptozocin-diabetic rats. Diabetes 34:611-616; 1985.
24. Madureira, M.L.C.; Adolfo, A.; Dias, J.; Sehe, M,; Carvalhais, H.A.; von Hafe, P. Reinnervation of the endocrine pancreas after autotransplantation of pancreatic fragments in the spleen of the dog: A morphofunctional study. World J. Surg. 9:335-347; 1985.
25. Mellgren, A.; Schnell Landström, A.H.; Petersson, B.; Andersson, A. The renal subcapsular site offers better growth conditions for transplanted mouse pancreatic islet cells than the liver or spleen. Diabetologia 29:670-672; 1986.
26. Nason, R.W.; Warnock, G.L.; Rajotte, R.V. Portal vs. systemic insulin delivery in canine pancreatic islet cell transplantation. Transplant. Proc. 20:1276-1278; 1988.
27. O'Brien, D.W.; Molnar, G.D.; O'Brien, D.C.; Rajotte, R.V. Portal vein insulin flux and arterial glucose fluctuations in response to an oral meal test in islet cell-transplanted dogs. Pancreas 9:543-549; 1994.
28. Portis, A.J.; Rajotte, R.V.; Krukoff, T.L. Reinnervation of isolated islets of Langerhans transplanted beneath the kidney capsule in the rat. Cell Transplant. 3:163-170; 1994.
29. Portis, A.J.; Warnock, G.L.; Finegood, D.T.; Belcastro, A.N.; Rajotte, R.V. Glucoregulatory response to moderate exercise in long-term islet cell autografted dogs. Can. J. Physiol. Pharmacol. 68:1308-1312; 1990.
30. Reece-Smith, H.; McShane, P.; Morris, P.J. Glucose and insulin changes following a renoportal shunt in streptozotocin diabetic rats with pancreatic islet isografts under the kidney capsule. Diabetologia 23:343-346; 1982.
31. Scheurink, A.J.W.; Steffens, A.B.; Bouritius, H.; Dreteler, G.; Bruntink, R.; Remie, R.; Zaagsma, J. Adrenal and sympathetic catecholamines in exercising rats. Am. J. Physiol. 256:R155-160; 1989.
32. Scheurink, A.J.W.; Steffens, A.B.; Bouritius, H.; Dreteler, G.; Bruntink, R.; Remie, R.; Zaagsma, J. Sympathoadrenal influence on glucose, FFA, and insulin levels in exercising rats. Am. J. Physiol. 256:R161-168; 1989.
33. Steffens, A.B. A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal. Physiol. Behav. 4:833-836; 1969.
34. Steffens, A.B.; Damsma, G.; Van der Gugten, J.; Luiten, P.G.M. Circulating free fatty acids, insulin and glucose during chemical stimulation of hypothalamus in rats. Am. J. Physiol. 247:E765-E771; 1984.
35. Strubbe, J.H.; Steffens, A.B. Blood glucose levels in portal and peripheral circulation and their regulation to food intake in the rat. Physiol. Behav. 19:303-304; 1977.
36. Strubbe, J.H.; Wolsink, J.G.; Schutte, A.M.; Balkan, B.; Prins, A.J.A.; Hepatic-portal and cardiac infusion of CCK-8 and glucagon induce different effects on feeding. Physiol. Behav. 46:643-646; 1989.
37. Van Dijk, G.; Balkan, B.; Lindfeldt, J.; Bouws, G.; Scheurink, A.J.W.; Ahrén, B.; Steffens, A,B. Contribution of liver nerves, glucagon, and adrenaline to the glycaemic response to exercise in rats. Acta Physiol. Scand. 150:305-313; 1994.
38. Van Suylichem, P.T.R.; Strubbe, J.H.; Houwing, H.; Wolters, G.H.J.; Van Schilfgaarde, R. Insulin secretion by rat islet isografts of a defined endocrine volume after transplantation to three different sites. Diabetologia 35: 917-923; 1992.
39. Van Suylichem, P.T.R.; Strubbe, J.H.; Houwing, H.; Wolters, G.H.J.; Van Schilfgaarde, R. Rat islet isograft function: Effect of graft volume and transplantation site. Transplantation 57:1010-1017; 1994.
40. Van Suylichem, P.T.R.; Wolters, G.H.J.; Van Schilfgaarde, R. The efficacy of density gradients for islet purification: A comparison of seven density gradients. Transplant. Int. 3:156-161; 1990.
41. Van Zwieten, P.A. The role of adrenoceptors in circulatory and metabolic regulation. Am. Heart J. 116:1384-1392; 1988.
42. Wamock, G.L.; Kneteman, N.M.; Rajotte, R.V. Islet transplantation. Experimental results and evolution of clinical trials. In: Samols, E., ed. The endocrine pancreas. New York: Raven Press Ltd.; 1991:487-517.
43. Wasserman, D.H.; Williams, P.E.; Lacy, D.B.; Goldstein, R.E.; Cherrington, A.D. Exercise-induced fall in insulin and hepatic carbohydrate metabolism during muscular work. Am. J. Physiol. 256:E500-E509; 1989.