Steroid-induced adipogenesis in a pluripotential cell line from bone marrow

Journal of Bone and Joint Surgery

Volumn 79, Issue 7, 1997, Pages 1054-1063

  Cui, Q ^a   Wang, G J ^a   Balian, G ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; DEXAMETHASONE; MESSENGER RNA; OSTEOCALCIN; STEROID; TRIACYLGLYCEROL;

ADIPOCYTE; ARTICLE; BONE MARROW; BONE NECROSIS; CELL DIFFERENTIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID STORAGE; MESENCHYME CELL; OSTEOBLAST; PRIORITY JOURNAL; STEM CELL; STROMA;

EID: 0030858452     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/00004623-199707000-00012     Document Type: Article

References (65)

1. Andersen, J., and Nielsen, H. E.: Osteonecrosis in renal transplant recipients. Early radiological detection and course. Acta Orthop. Scandinavica, 52: 475-479, 1981.
2. Anderson, P.; Moinfar, A.; and Balian, G.: Cultures of a cloned bone marrow cell are chondrogenic. Trans. Orthop. Res. Soc., 20: 462, 1995.
3. Arlet, J.: Nontraumalic avascular necrosis of the femoral head. Past, present, and future. Clin. Orthop., 277: 12-21, 1992.
4. 3 on osteogenic differentiation of human marrow stromal cells in vitro. Arch. Oral Biol., 39: 941-947, 1994.
5. Beresford, J. N.; Bennett, J. H.; Devlin, C.; Leboy, P. S.; and Owen, M. E.: Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures. J. Cell Sci., 102: 341-351, 1992.
6. Bernlohr, D. A.; Bolanowski, M. A.; Kelly, T. J., Jr.; and Lane, M. D.: Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes. J. Biol. Chem., 260: 5563-5567, 1985.
7. Bernlohr, D. A.; Angus, C. W.; Lane, M. D.; Bolanowski, M. A.; and Kelly, T. J., Jr.: Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc. Nat. Acad. Sci., 81: 5468-5472, 1984.
8. Bradbury, G.; Benjamin, J.; Thompson, J.; Klees, E.; and Copeland, J.: Avascular necrosis of bone after cardiac transplantation. Prevalence and relationship to administration and dosage of steroids. J. Bone and Joint Surg., 76-A: 1385-1388, 1994.
9. Bradford, D. S.; Janes, P. C; Simmons, R. S.; and Najarian, J. S.: Total hip arthroplasty in renal transplant recipients. Clin. Orthop., 181: 107-114, 1983.
10. Chan-Lam, D.; Prentice, A. G.; Copplestone, J. A.; Weston, M.; Williams, M.; and Hutton, C. W.: Avascular necrosis of bone following intensified steroid therapy for acute lymphoblastic leukaemia and high-grade malignant lymphoma. British J. Haematol., 86: 227-230, 1994.
11. Chapman, A. B.; Knight, D. M.; Dieckmann, B. S.; and Ringold, G. M.: Analysis of gene expression during differentiation of adipogenic cells in culture and hormonal control of the developmental program. J. Biol. Chem., 259: 15548-15555, 1984.
12. Cheneval, D.; Christy, R. J.; Geiman, D.; Cornelius, P.; and Lane, M. D.: Cell-free transcription directed by the 422 adipose P2 gene promoter: activation by the CCAAT/enhancer binding protein. Proc. Nat. Acad. Sci., 88: 8465-8469, 1991.
13. Cook, J. S.; Lucas, J. J.; Sibley, E.; Bolanowski, M. A.; Christy, R. J.; Kelly, T. J.; and Lane, M. D.: Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Proc. Nat. Acad. Sci., 85: 2949-2953, 1988.
14. Cornelius, P.; MacDougald, O. A.; and Lane, M. D.: Regulation of adipocyte development. Ann. Rev. Nutr., 14: 99-129, 1994.
15. Cruess, R. L.: Osteonecrosis of bone. Current concepts as to etiology and pathogenesis. Clin. Orthop., 208: 30-39, 1986.
16. Cruess, R. L.; Ross, D.; and Crawshaw, E.: The etiology of steroid-induced avascular necrosis of bone. A laboratory and clinical study. Clin. Orthop., 113: 178-183, 1975.
17. Cui, Q.; Wang, G. J.; and Balian, G-: Steroid-induced adipogenesis in bone marrow and osteonecrosis. ARCO News, 6: 117, 1994.
18. Delany, A. M.; Dong, Y.; and Canalis, E.: Mechanisms of glucocorticoid action in bone cells. J. Cell. Biochem., 56: 295-302, 1994.
19. Diduch, D. R.; Coe. M. R.; Joyner, C.; Owen, M. E.; and Balian, G.: Two cells from bone marrow that differ in terms of collagen synthesis, osteogenic characteristics, and matrix mineralization. J. Bone and Joint Surg., 75-A: 92-105, Jan. 1993.
20. Distel, R. J.; Ro, H. S.; Rosen, B. S.; Groves, D. L-; and Spiegelman, B. M.: Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos. Cell, 49: 835-844, 1987.
21. Dorheim, M. A.; Sullivan, M.; Dandapani, V.; Wu, X.; Hudson, J.; Segarini, P. R.; Rosen, D. M.; Aulthouse, M. L.; and Gimble, J. M.: Osteoblastic gene expression during adipogenesis in hematopoietic supporting murine bone marrow stromal cells. J. Cell. Physiol., 154: 317-328, 1993.
22. Elmstedt, E.: Avascular bone necrosis in the renal transplant patient: a discriminant analysis of 144 cases. Clin. Orthop., 158: 149-157, 1981.
23. Felson, D. T., and Anderson, J. J.: Across-study evaluation of association between steroid dose and bolus steroids and avascular necrosis of bone. Lancet, 1: 902-906, 1987.
24. Green, H., and Kehinde, O.: Sublines of mouse 3T3 cells that accumulate lipid. Cell, 1: 113-116, 1974.
25. Green, H., and Kehinde, O.: Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell, 7: 105-113, 1976.
26. Green, H., and Meuth, M.: An established pre-adipose cell line and its differentiation in culture. Cell, 3: 127-133, 1974.
27. Greenberger, J. S.: Corticosteroid-dependent differentiation of human marrow preadipocytes in vitro. In Vitro, 15: 823-828, 1979.
28. Grigoriadis, A. E.; Heersche, J. N.; and Aubin, J. E.: Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone. J. Cell Biol., 106: 2139-2151, 1988.
29. Gundle, R.: Joyner, C. J.; and Triffitt, J. T.: Human bone tissue formation in diffusion chamber culture in vivo by bone-derived cells and marrow stromal fibroblastic cells. Bone, 16: 597-601, 1995.
30. Harrington, K. D.; Murray, W. R.; Kountz, S. L.; and Belzer, F. O.: Avascular necrosis of bone after renal transplantation. J. Bone and Joint Surg.. 53-A: 203-215, March 1971.
31. Hungerford, D. S., and Lennox, D. W.: The importance of increased intraosseous pressure in the development of osteonecrosis of the femoral head: implications for treatment. Orthop. Clin. North America, 16: 635-654, 1985.
32. Hunt, C. R.; Ro, J. H.; Dobson, D. E.; Min, H. Y.; and Spiegelman, B. M.: Adipocyte P2 gene: developmental expression and homology of 5′-flanking sequences among fat cell-specific genes. Proc: Nat. Acad. Sd., 83: 3786-3790, 1986.
33. Ibels, L. S.; Alfrey, A. C.; Huffer, W. E.; and Weil, R-, III: Aseptic necrosis of bone following renal transplantation: experience in 194 transplant recipients and review of the literature. Medicine, 57: 25-45, 1978.
34. Jacobs, B.: Epidemiology of traumatic and nontraumatic osteonecrosis. Clin. Orthop., 130: 51-67,1978.
35. Jones, J. P., Jr.: Fat embolism and osteonecrosis. Orthop. Clin. North America, 16: 595-633, 1985.
36. Jones, J. P., Jr.: Etiology and pathogenesis of osteonecrosis. Sem. Arthroplasty, 2: 160-168, 1991.
37. Jones, J. P., Jr.: Intravascular coagulation and osteonecrosis. Clin. Orthop., 277: 41-53, 1992.
38. Jones, L. C., and Hungerford, D. S.: Models of ischemic necrosis of bone. In Bone Circulation, pp. 30-34. Edited by J. Arlet. H. P. Ficat, and D. S. Hungerford. Baltimore, Williams and Wilkins, 1984.
39. Julian, B. A.; Quarles, L. D.; and Niemann, K. M.: Musculoskeletal complications after renal transplantation: pathogenesis and treatment. Am. J. Kidney Dis., 19: 99-120, 1992.
40. Kaestner, K. H.; Ntambi, J. M.; Kelly, T. J., Jr.; and Lane, M. D.: Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase. J. Biol. Chem., 264: 14755-14761, 1989.
41. Kawai, K.; Tamaki, A.; and Hirohata, K.: Steroid-induced accumulation of lipid in the osteocytes of the rabbit femoral head. A histochemical and electron microscopic study. J. Bone and Joint Surg., 67-A: 755-763, June 1985.
42. Kawai, K.; Maruno, H.; Watanabe, Y.; and Hirohata, K.: Fat necrosis of osteocytes as a causative factor in idiopathic osteonecrosis in heritable hyperlipemic rabbits. Clin. Orthop., 153: 273-282, 1980.
43. Kempei, J. W.; Baggenstoss, A. H.; and Slocumb, C. H.: The relationship of therapy with cortisone to the incidence of vascular lesions in rheumatoid arthritis. Ann. Intern. Med., 46: 831-851, 1957.
44. Kodama, H. A.; Amagai, Y.; Koyama, H.; and Kasai, S.: Hormonal responsiveness of a preadipose cell line derived from newborn mouse calvaria. J. Cell Physioi., 112: 83-88, 1982.
45. Leboy, P. S.; Beresford, J. N.; Devlin, C.; and Owen, M. E.: Dexamethasone induction of osteoblast mRNAs in rat marrow stromal cell cultures. J. Cell Physiol., 146: 370-378, 1991.
46. Locklin, R. M.; Williamson, M. C.; Beresford, J. N.; Triffitt, J. T,; and Owen, M. E.: In vitro effects of growth factors and dexamethasone on rat marrow stromal cells. Clin. Orthop., 313: 27-35, 1995.
47. Mankin, H. J.: Nontraumatic necrosis of bone (osteonecrosis). New England J. Med., 326: 1473-1479, 1992.
48. Matsui, M.; Saito, S.; Ohzono, K.; Sugano, N.; Saito, M.; Takaoka, K.; and Ono, K.: Experimental steroid-induced osteonecrosis in adult rabbits with hypersensitivity vasculitis. Clin. Orthop., 277: 61-72, 1992.
49. Meunier, J.; Aaron, J.; Edouard, C.; and Vignon, G.: Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin. Orthop., 80: 147-154, 1971.
50. Ninomiya, S.: An epidemiological survey of idiopathic avascular necrosis of the femoral head in Japan. In Annual Report of Japanese Investigation Committee for Intractable Diseases, p. 269. Tokyo, Ministry of Health and Welfare, 1989.
51. Ntambi, J. M.; Buhrow, S. A.; Kaestner, K. H.; Christy, R. J.; Sibley, E.; Kelly, T. J., Jr.; and Lane, M. D.: Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. J. Biol. Chem., 263: 17291-17300, 1988.
52. Pietrogrande, V., and Mastromarino, R.: Osteopatia da prolungato trattamento cortisonico. Ortop. traumat. app. mot., 25: 791-810, 1957.
53. Pockwinse, S. M.; Stein, J. L.; Lian, J. B.; and Stein, G. S.: Developmental stage-specific cellular responses to vitamin D and gluco-corticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization. Exper. Cell Res., 216: 244-260, 1995.
54. Ringold, G. M.; Chapman, A. B.; and Knight, P. M.: Glucocorticoid control of developmentally regulated adipose genes. J. Steroid Biochem., 24: 69-75, 1986.
55. Rubin, C. S.; Lai, E.; and Rosen, O. M.: Acquisition of increased hormone sensitivity during in vitro adipocyte development. J. Biol. Chem., 252: 3554-3557, 1977.
56. Rubin, C. S.; Hirsch, A.; Fung, C.; and Rosen, D. M.: Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. J. Biol. Chem., 253: 7570-7578, 1978.
57. Russell, T. R., and Ho, R.: Conversion of 3T3 fibroblasts into adipose cells: triggering of differentiation by prostaglandin F2alpha and 1-methyl-3-isobutyl xanthine. Proc. Nat. Acad. Sci., 73: 4516-4520, 1976.
58. Smas, C. M., and Sul, H. S.: Control of adipocyte differentiation. Biochem. J, 309: 697-710, 1995.
59. Steinberg, M. E.: Osteonecrosis of the hip: summary and conclusions. Sem. Arthroplasty, 2: 241-249, 1991.
60. Stern, P. J., and Watts, H. G,: Osteonecrosis after renal transplantation in children. J. Bone and Joint Surg., 61-A: 851-856, Sept. 1979.
61. Tontonoz, P.; Hu, E.; and Spiegelman, B. M.: Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor Cell, 79: 1147-1156, 1994.
62. Wang, G. J.: Pathogenesis of steroid-induced avascular necrosis and its response to lipid clearing agent. In Trends in Research and Treatment of Joint Diseases, pp. 59-71. Edited by K. Hirohata, K. Mizuno, and T. Matsubara. Tokyo, Springer, 1992.
63. Wang, G.-J.; Sweet, D. E.; Reger, S. I.; and Thompson, R. C.: Fat-cell changes as a mechanism of avascular necrosis of the femoral head in cortisone-treated rabbits. J. Bone and Joint Surg., 59-A: 729-735, Sept. 1977.
64. Wang, G.-J.; Lennox, D. W.; Reger, S. I.; Stamp, W. G.; and Hubbard, S. L.: Cortisone-induced intrafemoral head pressure change and its response to a drilling decompression method, Clin. Orthop., 159: 274-278, 1981.
65. Weiner, F. R.; Smith, P. J.; Wertheimer, S.; and Rubin, C. S.: Regulation of gene expression by insulin and tumor necrosis factor alpha in 3T3-L1 cells. Modulation of the transcription of genes encoding acyl-CoA synthetase and stearoyl-CoA desaturase-1. J. Biol. Chem., 266: 23525-23528, 1991.