The effect of intravenous cyclophosphamide pulse on peripheral blood lymphocytes in lupus erythematosus patients

Rheumatology International

Volumn 17, Issue 2, 1997, Pages 55-60

  Lacki, J K ^a,b,c,d   Mackiewicz, S H ^c   Leszczynski, P ^c   Muller W ^a,b  

^a Hochrhein Inst Rheumatism Res P   (Germany)

^b Hochrhein Inst Rheumatism Res P   (Switzerland)

^c POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^d NONE   (Poland)

Author keywords

Cyclophosphamide; Lupus erythematosus; Lymphocytes

Indexed keywords

BETA1 INTEGRIN; CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2 RECEPTOR; LYMPHOCYTE ANTIGEN;

ADULT; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; FEMALE; FLOW CYTOMETRY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; NATURAL KILLER CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

ADULT; ANTIGENS, CD; ANTIRHEUMATIC AGENTS; CYCLOPHOSPHAMIDE; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MIDDLE AGED;

EID: 0030858289     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00006852     Document Type: Article

References (26)

1. Tan EM (1989) Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv Immunol 44: 93-116
2. Steinberg AD, Kreig AM, Gourley MF, Klinman DM (1990) Theoretical and experimental approaches to generalized autoimmunity. Immunol Rev 118: 129-163
3. Steinberg AD, Gourley MF, Klinman DM, Tsokos GC, Scott DE, Kreig AM (1991) Systemic lupus erythematosus. Ann Intern Med 115: 548-559
4. Hirohata S, Lipsky PE (1989) T cell regulation of human B cell proliferation and differentiation. Regulatory influences of CD45R+ and CD45R- T4 cell subsets. J Immunol 142: 2597-2607
5. Klinman DM, Steinberg A (1995) Inquiry into murine and human lupus. Immunol Rev 144: 157-193
6. Austin HA, Klippel JH, Balow JE, LeRiche NGH, Steinberg AD, Plotz PH, Decker JL (1986) Therapy of lupus nephritis. N Engl J Med 314: 614-619
7. Boumpas DT, Austin HA, Vaughn EM, Klippel JH, Steinberg AD, Yarboro CH, Balow JE (1992) Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis. Lancet 340: 741-745
8. Eiser AR, Grishman E, Dreznin S (1993) Intravenous pulse cyclophosphamide in treatment of type IV lupus nephritis. Clin Nephrol 40: 155-159
9. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25: 1271-1277
10. Dau PC, Callahan J, Parker R, Golbus J (1991) Immunologic effects of plasmapheresis synchronized with pulse cyclophosphamide in systemic lupus erythematosus. J Rheumatol 18: 270-276
11. Dau PC (1994) Immunomodulation during treatment of polymyositis with plasmapheresis and immunosuppressive drugs. J Clin Apheresis 9: 21-25
12. Dau PC, Callahan JP (1994) Immune modulation during treatment of systemic sclerosis with plasmapheresis and immunosupppressive drugs. Clin Immunol Immunopathol 70: 159-165
13. Moody DJ, Fahey JL, Grable E, Ellison GW, Myers LW (1987) Administration of monthly pulses of cyclophosphamide in multiple sclerosis patients. Delayed recovery of immune parameters following dicontinuation of long term cyclophosphamide treatment. J Neuroimmunol 14: 175-182
14. Bakke AC, Kirkland PA, Kitridou RC, Quismorio FP, Rea T, Ehresmann GR, Horwitz DA (1983) T lymphocyte subsets in systemic lupus erythematosus. Correlation with corticosteroid therapy and disease activity. Arthritis Rheum 26: 745-750
15. Smolen JS, Chused TM, Leiserson WM, Reeves JP, Alling D, Steinberg AD (1982) Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus. Correlation with clinical features. Am J Med 72: 783-790
16. Lanier LL, Ruitenberg JJ, Philips JH (1986) Human CD3+ T lymphocytes that express neither CD4 nor CD8 antigens. J Exp Med 164: 339-344
17. Theocharis S, Sfikakis PP, Lipnick RN, Klipple GL, Steinberg AD, Tsokos GC (1995) Characterization of in vivo mutated T cells clones from patients with systemic lupus erythematosus. Clin Immunol Immunopathol 74: 135-142
18. Koh DR, Ho A, Rahemtulla A, Fung-Leung WP, Griesser H, Mak TW (1995) Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells. Eur J Immunol 25: 2558-2562
19. Massa M, De Benedetti F, Robioni P, Ramenghi B, Albani S, Martini A (1993) Association of methotrexate treatment with a decrease of double negative (CD4- CD8-) and gamma/delta T cell levels in patients with juvenile rheumatoid arthritis. J Rheumatol 20: 1944-1948
20. Kantor S (1991) The development and repetoire of B-1 cells (CD5 B cells). Immunol Today 12: 389-391
21. Becker H, Weber C, Storch S, Federlin K (1990) Relationship between CD5+ B lymphocytes and the activity of systemic autoimmunity. Clin Immunol Immunopathol 56: 219-225
22. Markeljevic J, Batinic D, Uzarevic B, Bozikov J, Cikes N, Babic-Naglic D, Horvat Z, Marusic M (1994) Peripheral blood CD5+ B cells subset in the remission phase of systemic connective tissue diseases. J Rheumatol 21: 2225-2230
23. Fiocco U, Rosada M, Cozzi L, Ortolani L, De-Silvestro G, Rufatti A, Cozzi E, Gallo C, Todesco S (1993) Early phenotypic activation of circulating helper memory T cells in scleroderma: correlation with disease activity. Ann Rheum Dis 52: 272-277
24. Rohowsky-Kochan C, Eiman D, Troiano R, Bansil S, Oleske J, Denny T, Cook SD (1990) Decreased suppressor inducer T lymphocytes in multiple sclerosis and other neurological disease. J Neuroimmunol 28: 161-166
25. Nobutoh T, Kohda M, Ueki H (1994) Decreased CD4+ CD45RA+ lymphocytes in peripheral blood of systemic lupus erythematosus can recover after separation from patients sera. J Dermatol Sci 7: 185-190
26. Al-Janadi M, Raziuddin S (1993) B-cell hyperactivity is a function of T-cell derived cytokines in systemic lupus erythematosus. J Rheumatol 20: 1885-1891