MHC class I antigen expression in patients with IDDM and their siblings

Journal of Pediatric Endocrinology and Metabolism

Volumn 10, Issue 4, 1997, Pages 391-394

  Anal, Özden ^a,b   Akkoç, Nurullah ^a   Sen, Alp ^a   Yesil, Sena ^a   Yüksel, Faize ^b   Büyükgebiz, Atilla ^a  

^a School of Medicine   (Turkey)

^b DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

IDDM; Lymphocyte; MHC class I antigen

Indexed keywords

ADOLESCENT; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNITY; CELL SURFACE; CHILD; CLINICAL ARTICLE; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HUMAN; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE COUNT; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PANCREAS ISLET BETA CELL; VEIN BLOOD FLOW;

EID: 0030858167     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.1997.10.4.391     Document Type: Article

References (15)

1. Tarn AC, Thomas JM, Dean BM. Predicting insulin dependent diabetes. Lancet 1988; 1:845-850.
2. Plotnick L. Insulin dependent diabetes mellitus. Pediatr Rev 1994; 15: 137-148.
3. Livingstone AM, Powis SJ, Diamond AG, Butcher GW, Howard JC. A trans-acting major histocompatibility complex-linked gene whose alleles determine gain and loss changes in the antigenic structure of a classical class I molecule. J Exp Med 1989; 170: 777.
4. Faustman D, Li X, Lin HY, Fu Y, Eisenbarth G, Avruch J, Guo J. Linkage of faulty major histocompatibility complex class I to autoimmune diabetes. Science 1991; 254: 1756-1761.
5. Eisenbarth GS, Verge CF, Allen H, Rewers MJ. The design of trials for prevention of IDDM. Diabetes 1993; 42: 941-947.
6. Pozzilli P. Prevention of type I diabetes mellitus. Diab Nutr Metab 1994; 7: 57-61.
7. Skyler JS, Marks JB. Immune intervention in type I diabetes mellitus. Diabetes Rev 1993; 1: 15-42.
8. Elliott RD, Chase HP. Prevention or delay of type I (insulin dependent) diabetes mellitus in children using nicotinamide. Diabetologia 1991; 34: 362-365.
9. Laron Z, Karp M, eds. Genetic and Environmental Risk Factors for Type I Diabetes (IDDM). Tel Aviv-London: Freund Publishing House Ltd., 1992.
10. Itoh N, Hanafusa T, Miyazaki A, Miyagawa J, Yamagata K, Yamamoto K, Waguri M, Imagawa A, Tamura S, Inada M. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest 1993; 92: 2313-2322.
11. Wang F, Li X, Annis B, Faustman DL. Tap-1 and Tap-2 gene therapy selectively restores conformationally dependent HLA class I expression in type I diabetic cells. Hum Gene Ther 1995; 6: 1005-1017.
12. Kay TWH, Campbell IL, Oxbrow L, Harrison LC. Overexpression of class I major histocompatibility complex accompanies insulitis in the non-obese diabetic mouse and is prevented by anti-interferon-γ antibody. Diabetologia 1991; 34: 779-785.
13. Somoza N, Vargas F, Roura Mir C, Vives Pi M, Fernandex-Figueras MT, Ariza A, Gomis R, Bragado R, Marti M, Jaraquemada D. Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile. J Immunol 1994; 153: 1360-1377.
14. Yesil S, Hatemi H, Hacibekiroglu M. Tiroid hastaliklarinda beta2 mikroglobulinin tiroid fonksiyonlari, otoimmunite ve nodul olusumu ile iliskisi. In: XIXth Turkish National Meeting of Endocrinology and Diabetes, 28-31 May 1996, Istanbul (abstract).
15. Anal Ö, Yesil S, Akkoç N, Böber E, Yüksel F, Büyükgebiz A. MHC class I antigen expression in patients with autoimmune thyroid disease (ongoing study).