The effects of intraventricular/periventricular blood on cerebral 3',5'- cyclic adenosine monophosphate concentration and cerebrovascular reactivity in newborn pigs

Pediatric Research

Volumn 42, Issue 3, 1997, Pages 305-310

  Pourcyrous, Massroor ^a,b   Parfenova, Helena ^a   Shibata, Masaaki ^a,c   Bada, Henrietta S ^a   Korones, Sheldon B ^a   Leffler, Charles W ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Newborn Center   (United States)

^c UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; CAUDATE NUCLEUS; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 0030857468     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199709000-00010     Document Type: Article

References (34)

1. Volpe JJ, Herscovich P, Perlman JM, Raichle ME 1983 Positron emission tomography in the newborn. Intensive impairment of regional cerebral blood flow with intraventricular hemorrhage and hemorrhagic intracerebral involvement. Pediatrics 72:589-601
2. Parfenova H, Shibata M, Leffler CW 1993 Subarachnoid blood causes pial arteriolar constriction in newborn pigs. Stroke 24:1729-1734
3. Mizukami M, Kawase T, Usami T, Tazawa T 1982 Prevention of vasospasm by operation with removal of subarachniod blood. Neurosurgery 10:301-307
4. Bada HS 1983 Intracranial monitoring. Its role and application in neonatal intensive care. Clin Perinatol 10:223-236
5. Ment LR, Duncan CC, Ehrenkranz RA, Lange RC, Taylor KJ, Kleinman CS, Scott DT, Sivo J, Gettner P 1984 Intraventricular hemorrhage in the preterm neonates: timing and cerebral blood flow changes. J Pediatr 104:419-425
6. Hatake K, Wakabayashi I, Kakishita E, Hishida S 1992 Impairment of endothelium-dependent relaxation in human basilar artery after subarachnoid hemorrhage. Stroke 23:1111-1117
7. 2 reactivity during delayed vasospasm in a canine model of subarachnoid hemorrhage. Stroke 22:367-372
8. Yakuhu MA, Shibata M, Leffler CW 1994 Subarachnoid hematoma attenuates vasodilation and potentiates vasoconstriction induced by vasoactive agents in newborn pigs. Pediatr Res 36:589-594
9. 4 and endothelin-1 piglets: role of prostanoids. Pediatr Res 38:119-123
10. Heros RC, Zervas NT, Varsos V 1983 Cerebral vasospasm after subarachnoid hemorrhage: an update. Ann Neurol 14:599-608
11. White RP, Leffler CW, Bada HS 1990 Eicosanoid levels in CSF of premature infants with posthemorrhagic hydrocephalus. Am J Med Sci 299:230-235
12. Tigyi G, Hong L, Yakubu M, Parfenova H, Shibata M, Leffler CW 1995 Lysophosphatidic acid alters cerebrovascular reactivity in piglets. Am J Physiol 268:H2048-H2055
13. Findlay JM, MacDonald LR, Weir KA 1991 Current concepts of pathophysiology and management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Cerebrovasc Brain Metab 3:336-361
14. MacDonald RL, Weir BKA 1991 A review of hemoglobin pathogenesis of cerebral vasospasm. Stroke 22:971-982
15. Parfenova H, Shibata M, Zuckerman S, Mirro R, Leffler CW 1993 Cyclic nucleotides and cerebrovascular tone in newborn pigs. Am J Physiol 265:H1972-H1982
16. Dixon WJ, Massey FJ 1969 Introduction to Statistical Analysis, 3rd Ed. McGraw-Hill, New York, pp 330-332
17. Wolfe LS 1982 Eicosanoids: prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 unsaturated fatty acids. J Neurochem 38:1-14
18. Busija DW, Leffler CW 1991 Selective attenuation by perivascular blood of prostanoid-dependent cerebrovascular dilation in piglets. Stroke 22:484-488
19. Busija DW, Leffler CW 1990 Perivascular blood attenuates noradrenergic but not cholinergic effects on piglet pial arterioles. Stroke 21:441-446
20. Walker V, Pickard JD 1985 Prostaglandins, thromboxane, leukotrienes and cerebral circulation in health and disease. Adv Tech Stand Neurosurg 12:3-9
21. Leffler CW, Armstead WM, Shibata M 1993 Role of the eicosanoids in cerebral hemodynamics. In: Phillis JW (ed) The Regulation of Cerebral Blood Flow. CRC Press, Ann Arbor, MI, pp 297-313
22. Sasaki T, Murota S, Wakai S, Asano T, Sano K 1981 Evaluation of prostaglandin biosynthetic activity in canine basilar artery following subarachnoid injection of blood. J Neurosurg 55:771-778
23. Rodriguez Y, Baena R, Gaetani P, Paoletti P 1988 A study on cisternal CSF levels of arachidonic acid metabolites after aneurysmal subarachnoid hemorrhage. J Neurosurg 84:329-335
24. Mirro R, Armstead WM, Mirro J, Busija DW, Leffler CW 1989 Blood-induced superoxide generation on the cerebral cortex of newborn pigs. Am J Physiol 257:H1560-H1564
25. Shishi T, Suzuki R, Qian L, Hirakawa K 1994 The role of superoxide anions in the pathogenesis of cerebral vasospasm. Stroke 25:864-868
26. Leffler CW, Mirro R, Shanklin DR, Armstead WM, Shibata M 1994 Light/dye microvascular injury selectively eliminates hypercapnia-induced pial arteriolar dilation in newborn pigs. Am J Physiol 266:H623-H630
27. Mirro R, Busija DW, Armstead WM, Leffler CW 1988 Histamine dilates pial arterioles of newborn pigs through prostanoid production. Am J Physiol 254:H1025-H1026
28. Wablgren NG, Bergstrom K 1983 Determination of human derivatives in the cerebral spinal fluid-a semi-quantitative method. J Neurosurg Psychiatry 46:653-658
29. Wever R, Oudega B, VanGelder BF 1973 Generation of superoxide radicals during the autoxidation of mammalian oxyhemoglobin. Biochim Biophys Acta 302:475-478
30. Hillered L, Ernster L 1983 Respiratory activity of isolated rat brain mitochondria following in vitro exposure to oxygen radicals. J Cereb Blood Flow Metab 3:207-214
31. Ohlstein EH, Storer BL 1992 Oxyhemoglobin stimulation of endothelin production in cultured endothelial cells. J Neurosurg 77:274-278
32. Suzuki H, Sato S, Suzuki Y, Takekoshi K, Ishihara N, Shimoda S 1990 Increased endothelin concentration in CSF from patients with subarachnoid hemorrhage. Acta Neurol Scand 81:553-554
33. 2 accumulation in rat IMCD. Am J Physiol 265:F670-F676
34. Yakubu M, Liliom K, Tigyi GJ, Leffler CW 1997 Role of lysophosphatidic acid in endothelin-1 and hematoma-induced alteration of cerebral circulation. Am J Physiol 273[42]R (in press)